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[null,"1.","Record Nr.",null,"UNINA9910418314903321"]
[null,null,"Autore",null,"Dickmann Martin"]
[null,null,"Titolo",null,"Messung von Experimentierfä higkeiten : Validierungsstudien zur Qualitäta eines computerbasierten Testverfahrens / / Martin Dickmann"]
[null,null,"Pubbl/distr/stampa",null,"Berlin/Germany, : Logos Verlag Berlin, 2016"]
[{"$nulls":4},"Berlin, Germany : , : Logos Verlag Berlin, , [2016]"]
[{"$nulls":4},"©2016"]
[null,null,"ISBN",null,"3-8325-9840-5"]
[null,null,"Descrizione fisica",null,"1 online resource (210 pages) : illustrations, charts; digital file(s)"]
[null,null,"Collana",null,"Studien zum Physik- und Chemielernen ; ; 210"]
[null,null,"Disciplina",null,"153.94"]
[null,null,"Soggetti",null,"Ability - Testing"]
[null,null,"Lingua di pubblicazione",null,"Tedesco"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Author's doctoral thesis: Universität Duisburg Essen -- page [1]."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,null,"Sommario/riassunto","Long description: Die vorliegende Arbeit beschäftigt sich mit der Validierung eines neuen Tests zur Messung von Experimentierfähigkeit in Large-Scale-Assessments. Die Testaufgaben erfordern die Planung, Durchführung und Auswertung typischer physikalischer Schülerexperimente der Sekundarstufe I. Anstelle von Realexperimenten werden interaktive Simulationen zum Aufbau von Experimenten und zur Durchführung von Messungen eingesetzt. Die Bearbeitung der Testaufgaben erfolgt vollständig am Computerbildschirm. Diesen Bearbeitungen werden in der Auswertung Punkte (Testwerte) zugewiesen.  In der heute gültigen Vorstellung ist Validierung im Wesentlichen als ein theorie- und evidenzbasierter Argumentationsprozess aufzufassen. Nach der Nennung und Begründung notwendiger Validierungsschritte erfolgt eine schlüssige Validitätsargumentation. Ein Validierungsschritt kann z. B. darin bestehen, zu überprüfen, in wieweit zur erfolgreichen Bearbeitung der Testaufgaben Experimentierfähigkeiten eingesetzt werden.  Die Ergebnisse der Validierungsschritte lassen sich wie folgt zusammenfassen: die Aufgabeninhalte und -anforderungen des Tests passen zum Physikunterricht der Sekundarstufe I; die Schüler denken und handeln bei der Bearbeitung der Testaufgaben experimentell; der verwendete Bewertungsmaßstab misst Experimentierfähigkeit; die erreichten Testwerte korrelieren mit den Testwerten, die bei inhaltlich identischen Realexperimenten erreicht werden. Zusammenfassend ist "]
[{"$nulls":4},"festzuhalten, dass der computerbasierte Test das Spektrum der in Large-Scale Assessments erfassbaren Experimentierfähigkeiten erweitert."]
[null,"2.","Record Nr.",null,"UNINA9910261133203321"]
[null,null,"Autore",null,"Manoj B. Menon"]
[null,null,"Titolo",null,"Emerging Functions of Septins"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2017"]
[null,null,"Descrizione fisica",null,"1 online resource (126 p.)"]
[null,null,"Collana",null,"Frontiers Research Topics"]
[null,null,"Soggetti",null,"Biology, life sciences"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Together with the microfilament, microtubule and intermediate-filament networks, septins constitute an integral part of the eukaryotic cytoskeleton. Historically identified as proteins critical for septum formation in the budding yeast Saccharomyces cerevisiae, septin family GTPases are expressed and participate in the process of cytokinesis in most eukaryotes except higher plants. More than a dozen septin genes in mammals, together with various splice variants displaying tissue-specific expression patterns and flexible hetero-polymeric higher-order assembly achieve an unfathomable complexity superior to the other cytoskeletal components. Even though the initial studies in the septin field was restricted to their evolutionarily conserved role in cell division, strong expression of septins in the non-dividing cells of the brain generated great interest in understanding their role in neuronal morphogenesis and other aspects of cellular function. On one hand, recent developments indicate complex non-canonical roles for septins in diverse processes ranging from neuronal development to immune response and calcium signaling. On the other hand several lines of data including those from knockout models question the universal role for septins in animal cell cytokinesis. Mammalian hematopoietic cells seem to proliferate and efficiently undergo cytokinesis in the absence of pivotal septin proteins in a context-dependent manner. The lack of septin-dependence of hematopoiesis also opens the possibility of safely targeting septin-dependent cytokinesis for solid-tumor therapy. Thus the septin field is perfectly poised with novel roles for septins being discovered and the basic understanding on septin assembly and its canonical functions constantly revisited. The objective of this "]
[{"$nulls":4},"research topic was to provide an exclusive platform for discussing these rapid advances in the septin field. With a mixture of reviews and research articles encompassing diverse areas of septin research, ranging from the humble yeast model to human cancer, this ebook will be an interesting reading material for both experts as well as new comers to the septin field."]