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[null,"1.","Record Nr.",null,"UNINA9910254051003321"]
[null,null,"Autore",null,"Kinoshita Masahiro"]
[null,null,"Titolo",null,"Mechanism of Functional Expression of the Molecular Machines / / by Masahiro Kinoshita"]
[null,null,"Pubbl/distr/stampa",null,"Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016"]
[null,null,"ISBN",null,"981-10-1486-8"]
[null,null,"Edizione",null,"[1st ed. 2016.]"]
[null,null,"Descrizione fisica",null,"1 online resource (X, 70 p. 30 illus., 24 illus. in color.)"]
[null,null,"Collana",null,"SpringerBriefs in Molecular Science, , 2191-5407"]
[null,null,"Disciplina",null,"539.6"]
[null,null,"Soggetti",null,"Chemistry, Physical and theoretical"]
[{"$nulls":4},"Biophysics"]
[{"$nulls":4},"Proteins"]
[{"$nulls":4},"Statistical physics"]
[{"$nulls":4},"Dynamics"]
[{"$nulls":4},"Physical Chemistry"]
[{"$nulls":4},"Biological and Medical Physics, Biophysics"]
[{"$nulls":4},"Protein-Ligand Interactions"]
[{"$nulls":4},"Complex Systems"]
[{"$nulls":4},"Statistical Physics and Dynamical Systems"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references at the end of each chapters."]
[null,null,"Nota di contenuto",null,"Introduction -- Importance of Translational, Configurational Entropy of Water -- Molecular Machines -- Concluding Remarks: Mechanism of Functional Expression Common in the Molecular Machines."]
[null,null,null,"Sommario/riassunto","This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules "]
[{"$nulls":4},"coexisting with the molecular machines in the entire system."]