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[null,"1.","Record Nr.",null,"UNINA9911002546003321"]
[null,null,"Titolo",null,"Biotechnology and Cancer Therapeutics / / edited by Manisha Nigam, Abhay Prakash Mishra"]
[null,null,"Pubbl/distr/stampa",null,"Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2025"]
[null,null,"ISBN",null,"981-9649-59-5"]
[null,null,"Edizione",null,"[1st ed. 2025.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XVIII, 478 p. 41 illus.)"]
[null,null,"Collana",null,"Interdisciplinary Biotechnological Advances, , 2730-7077"]
[null,null,"Disciplina",null,"660.6"]
[null,null,"Soggetti",null,"Biotechnology"]
[{"$nulls":4},"Cancer"]
[{"$nulls":4},"Therapeutics"]
[{"$nulls":4},"Nanomedicine"]
[{"$nulls":4},"Diagnosis"]
[{"$nulls":4},"Cancer Biology"]
[{"$nulls":4},"Cancer Nanotechnology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"-- Chapter 1: Biotechnology in Medicine: Fundamentals  -- Chapter 2: Molecular Diagnosis in Cancer  -- Chapter 3: Cancer Immunotherapy  -- Chapter 4: RNAi in Cancer Therapy - RNA Interference (RNAi): A Promising Frontier in Cancer Therapy - Mechanisms, Challenges, and Future Perspectives  -- Chapter 5: Cell Therapy of Cancer  -- Chapter 6: Personalized Cancer Therapy  -- Chapter 7: Drug Resistance and Novel Targets for Cancer Therapy  -- Chapter 8: Epigenetics: Applications in Cancer Therapeutics  -- Chapter 9: Biomarkers of Cancer  -- Chapter 10:Small molecules in targeted cancer therapy  -- Chapter 11:Monoclonal Antibodies and Cancer  -- Chapter 12:Role of MicroRNAs in Cancer  -- Chapter 13:Gene therapy of cancer  -- Chapter 14:Biotechnology in drug discovery and development for cancer."]
[null,null,null,"Sommario/riassunto","This book explores new ground in the field of cutting-edge cancer treatment modalities by presenting contemporary biotechnological developments as a component of cancer targeting techniques. It addresses the application of modern technologies in cancer detection, targeting, and the development of therapeutic strategies across fifteen comprehensive chapters. The book emphasizes the advantages of molecular techniques for cancer therapies, such as molecular "]
[{"$nulls":4},"diagnosis, cell and gene therapy, and immunotherapy, with a dedicated chapter on personalized cancer therapy to critically analyze the progression toward precision strategies. The chapters cover topics such as molecular biomarkers, microRNAs, and the potential of nanomedicine in cancer treatment. The authors provide expert analysis on the latest research, offering insights into the outcomes of scientific and clinical trials. Readers will also discover discussions on drug resistance, novel molecular targets, and the integration of biotechnology in drug discovery and development. Particular attention is given to the role of epigenetics and RNA interference in cancer therapy, as well as the challenges and future prospects of personalized medicine. This book is designed specifically for oncologists, cancer biologists, researchers, academicians, and students interested in understanding the most cutting-edge biotechnological aspects of cancer therapeutics. It offers a comprehensive overview of cancer prevention, therapeutics, and treatments through the perspectives of technology, medicine, and alternative therapies. Researchers in the field of biotechnology and cancer therapy will find this book invaluable for its detailed discussions and insights into the latest advancements. It serves as a crucial tool for those working in this area, providing a valuable resource for understanding the complexities of cancer therapies and fostering progress in the field. ."]
[null,"2.","Record Nr.",null,"UNINA9910253934003321"]
[null,null,"Titolo",null,"Protein Reviews : Volume 18 / / edited by M. Zouhair Atassi"]
[null,null,"Pubbl/distr/stampa",null,"Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017"]
[null,null,"ISBN",null,"981-10-6922-0"]
[null,null,"Edizione",null,"[1st ed. 2017.]"]
[null,null,"Descrizione fisica",null,"1 online resource (VIII, 203 p. 50 illus., 46 illus. in color.)"]
[null,null,"Collana",null,"Protein Reviews, , 2520-1891 ; ; 966"]
[null,null,"Disciplina",null,"574.19245"]
[null,null,"Soggetti",null,"Proteins"]
[{"$nulls":4},"Protein Structure"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Mechanism of channel gating and regulation of the activity of calcium-activated chloride channel ANO1 -- Structure and function of the two-component cytotoxins of Staphylococcus aureus -- Membrane Fusion and Infection of the Influenza Hemagglutinin -- Deciphering the impact of arrhythmogenic mutations through the structural determination of the L-type voltage-gated calcium channel -- Histone post-translational modifications and nucleosome organisation in transcriptional regulation: Some open questions -- Regulation of the extracellular SERPINA5 (protein C inhibitor) penetration through cellular membranes -- Coding of Class I and II aminoacyl-tRNA synthetases -- Regulation of nephrin phosphorylation in diabetes and chronic kidney injury -- The Structure-Forming Juncture in Oxidative Protein Folding: What happens in the ER? -- Polyspecificity of Anti-Lipid A Antibodies and its Relevance the Development of Autoimmunity."]
[null,null,null,"Sommario/riassunto","The aim of the Protein Reviews is to serve as a publication vehicle for review articles that focus on crucial current vigorous aspects of protein structure, function, evolution and genetics. The volumes will appear online before they are published in a printed book. Articles are selected according to their importance to the understanding of biological systems, their relevance to the unravelling of issues associated with health and disease or their impact on scientific or technological advances and developments. The chapters in volume 18 are authored by experts in the field. They deal with aspects of structure and/or biological activity of selected proteins. The chapters review current research of the following topics: the Mechanism of channel gating and regulation of the activity of calcium-activated chloride channel ANO1, "]
[{"$nulls":4},"Structure and function of the two-component cytotoxins of Staphylococcus aureus, Membrane Fusion and Infection involving the influenza virus hemagglutinin, The impact of arrhythmogenic mutations through the structural determination of the L-type voltage-gated calcium channel, Discussion of some open questions pertaining to histone post-translational modifications and nucleosome organization in transcriptional regulation, Regulation of the extracellular SERPINA5 (protein C inhibitor) penetration through cellular membranes, Coding of Class I and II aminoacyl-tRNA synthetases, Nephrin phosphorylation in diabetes and chronic kidney injury, The structure-forming juncture in oxidative protein folding and the events in the ER, The polyspecificity of anti-lipid antibodies and its relevance to the development of autoimmunity. This volume is intended for research scientists, clinicians, physicians and graduate students in the fields of biochemistry, cell biology, molecular biology, immunology and genetics."]