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[null,"1.","Record Nr.",null,"UNINA9910830381603321"]
[null,null,"Titolo",null,"Angiogenesis assays [[electronic resource] ] : a critical appraisal of current techniques / / [edited by] Carolyn A. Staton, Claire Lewis, Roy Bicknell"]
[null,null,"Pubbl/distr/stampa",null,"Chichester, England ; ; Hoboken, NJ, : J. Wiley & Sons, c2006"]
[null,null,"ISBN",null,"1-280-73958-4"]
[{"$nulls":4},"9786610739585"]
[{"$nulls":4},"0-470-02935-8"]
[{"$nulls":4},"0-470-02934-X"]
[null,null,"Descrizione fisica",null,"1 online resource (420 p.)"]
[null,null,"Disciplina",null,"612.130724"]
[null,null,"Soggetti",null,"Blood-vessels - Growth"]
[{"$nulls":4},"Neovascularization"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Endothelial cell biology / Femke Hillen, Veerie Meloote, Judy R. van Beijnum and Arjan W. Griffioen -- Endothelial cell proliferation assays / Wen-Sen Lee -- Endothelial cell migration assays / Christos Polytarchou, Maria Hatziapostolou and Evangelia Papadimitriou -- Tubule formation assays / Ewen J. Smith and Carolyn A. Staton -- Modelling the effects of the haemodynamic environment on endothelial cell responses relevant to angiogenesis / Gerard B. Nash and Stuart Egginton -- Whole or partial vessel outgrowth assays / Cindy H. Chau and William D. Figg -- Assaying endothelial mural cell interactions / Melissa K. Nix and Karen K. Hirschi -- Assays for membrane and intracellular signalling events / Vittorio Tomasi, Cristiana Griffoni, Spartaco Santi, Patrizia Lenaz, Rosa Anna Iorio, Antonio Strillacci and Enzo Spisni -- Implantation of sponges and polymers / Silvia P. Andrade, Monica A. N. D. Ferreira, and Tai-Ping Fan -- Angiogenesis assays in the chick / Andries Zijlstra, David Mikolon and Dwayne G. Stupack -- Corneal angiogenesis assay / Siqing Shan and Mark W. Dewhirst --"]
[{"$nulls":4},"Dorsal air sac model / Sei Yonezawa, Tomohiro Asai and Naoto Oku -- Chamber assays / Michael D. Menger, Matthias W. Laschke and Brigitte Vollmar -- Tumour models : analysis of angiogenesis in vivo / Sven A. Lang and Oliver Stoeltzing -- Angiomouse : imageable models of "]
[{"$nulls":4},"angiogenesis / Robert M. Hoffman -- Techniques and advances in vascular imaging in Danio rerio / Kenna R. Mills Shaw and Brant M. Weinstein -- Biological and clinical implications of recruitment of stem cells into angiogenesis / Gianluigi Castoldi, Antonio Cuneo and Gian Matteo Rigolin -- Methods for monitoring of the anti-angiogenic activity of agents in patients : novel trial design / Shannon Smiley, Michael K. K. Wong and Shaker A. Mousa -- An overview of current angiogenesis assays : choice of assay, precautions in interpretation, future requirements and directions / Robert Auerbach."]
[null,null,null,"Sommario/riassunto","Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necess"]
[null,"2.","Record Nr.",null,"UNINA9910253931303321"]
[null,null,"Titolo",null,"Catharanthus roseus : Current Research and Future Prospects / / edited by M. Naeem, Tariq Aftab, M. Masroor A. Khan"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017"]
[null,null,"ISBN",null,"3-319-51620-5"]
[null,null,"Edizione",null,"[1st ed. 2017.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XII, 412 p. 43 illus., 30 illus. in color.)"]
[null,null,"Disciplina",null,"571.32"]
[null,null,"Soggetti",null,"Plants - Development"]
[{"$nulls":4},"Biotechnology"]
[{"$nulls":4},"Pharmaceutical chemistry"]
[{"$nulls":4},"Plant genetics"]
[{"$nulls":4},"Plant biotechnology"]
[{"$nulls":4},"Plants - Evolution"]
[{"$nulls":4},"Plant Development"]
[{"$nulls":4},"Pharmaceutics"]
[{"$nulls":4},"Plant Genetics"]
[{"$nulls":4},"Plant Biotechnology"]
[{"$nulls":4},"Plant Evolution"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"1.Strategies for enhancing alkaloids yield in Catharanthus roseus via Metabolic Engineering Approaches (Kexuan Tang and Qifang Pan) -- 2.In vitro biotechnological production & pharmacological studies of anti-leukemic alkaloids of Catharanthus roseus (Hebert Jair Barrales Cureño,Petra Andrade Hoyos, Alfonso Luna Cruz, Cesar Reyes Reyes, Salvador Chávez Salinas and Luis German Valdez López) -- 3.Plant efficiency and alkaloids production in Sadabahar (Catharanthus roseus L.): Role of potent PGRs and mineral nutrients (M. Naeem1, Tariq Aftab1, Mohd. Idrees, M. Masidur Alam, M. Masroor A. Khan and Moinuddin) -- 4. Role of Biotechnology in Alkaloids Production (Amjad Khalil) -- 5.Agricultural, pharmaceutical & Therapeutic Interior of Catharanthus Roseus (L.) (Md. Abul Barkat1, Harshita and Md. Akhlaquer Rahman) -- 6.Elicitation enhances alkaloid yield in Catharanthus roseus (Dipti Tonk, A. Mujib, Muzamil Ali and Nadia Zafar) -- 7. Catharanthus roseus: The "]
[{"$nulls":4},"Cancer-fighting Medicine (D. Sathya Prabhu, V. Devi Rajeswari) -- 8. In vitro studies, biosynthesis of secondary metabolites and pharmacological utility of Catharanthus roseus (L.) Don. - A review (P. Senbagalakshmi1, M.V. Rao and T. Senthil Kumar) -- 9. Therapeutic efficacy of Catharanthus roseus in Type 1 and Type 2 diabetes mellitus in wistar rats (Rasineni Karuna1, Gujjala Sudhakar, Sagree Saisree, Putakala Mallaiah, Bongu Sasibhusana Rao, Bellamkonda Ramesh, S. Sreenivasa Reddy and Desireddy Saralakumari) -- 10. Biotechnological interventions to modulate terpenoid indole alkaloid pathway in Catharanthus roseus using in vitro tools and approaches (Priyanka Verma, Shamshad Ahmad Khan, Varsha Parasharami and Ajay Kumar Mathur) -- 11. Vincristine and Vinblastine anticancer Catharanthus alkaloids: Pharmacological applications and strategies for yield improvement (Masidur Alam, M. Naeem, M. Masroor A. Khan and Moin Uddin) -- 12. Role of PGRs in anticancer alkaloids (vincristine & vinblastine) production (Jagjit Kaur, Apoorva Singh, Teena Pathak and Kuldeep Kumar) -- 13. The accumulation and degradation of alkaloids in Catharanthus roseus supported by various external agents under different environmental conditions (Mohd Idrees, Israr Ul Hassan, M. Naeem, Akbar Ali, Tariq Aftab, M. Masroor A. Khan) -- 14. Catharanthus roseus: Detoxification and hepatic protection of Aflatoxin B1 (S. Patharajan1, S. Bala Abirami, R. Elangomathavan and S. Ramesh) -- 15. Potential of Catharanthus roseus (L.): phytoremediation of Heavy Metals (V. Subhashini* and A.V.V.S. Swamy) -- 16. Unraveling the cumulative effect of soil-applied Radiation-processed sodium alginate and polyacrylamide on growth attributes, physiological activities and alkaloids production in periwinkle [Catharanthus roseus (L.) G. Don] (Asfia Shabbir, Akbar Ali, Yawar Sadiq, Hasan Jaleel, Bilal Ahmad, M. Naeem, M. Masroor A. Khan and Moinuddin) -- 17. Catharanthus roseus – Cultivation under Stress Conditions (Sanjeev Pandey) -- 18. The study of the effect of nickelheavy metal on some growth parameters and production of alkaloid in Catharantus roseus (Matin Arefi Fard)."]
[null,null,null,"Sommario/riassunto","This book studies the production of indole alkaloids in the important medicinal plant Catharanthus roseus (L.) G. Don, commonly known as periwinkle. The anticancer alkaloids, viz. vinblastine and vincristine, are mainly present in the leaves of C. roseus and inhibit the growth of cancer cells by hindering the formation of mitotic apparatus during cell division. Further, vinblastine helps increase the chance of surviving childhood leukemia while vincristine is used to treat Hodgkin’s disease. Great efforts have been made to produce these alkaloids at a large scale by the culture of plant cells. In view of this worldwide demand for commercial use, this book explores how to maximize the production of anticancer alkaloids from C. roseus. This reference book will be helpful for research students, teachers, ethnobotanists, pharmacologists and herbal growers who have a strong interest in this anticancer medicinal plant of paramount importance."]