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[null,"1.","Record Nr.",null,"UNINA9910144747203321"]
[null,null,"Titolo",null,"Metastasis [[electronic resource]]"]
[null,null,"Pubbl/distr/stampa",null,"Chichester, UK ; ; New York, : Wiley, 1988"]
[null,null,"ISBN",null,"1-282-34758-6"]
[{"$nulls":4},"9786612347580"]
[{"$nulls":4},"0-470-51373-X"]
[{"$nulls":4},"0-470-51374-8"]
[null,null,"Descrizione fisica",null,"1 online resource (268 p.)"]
[null,null,"Collana",null,"Ciba Foundation symposium ; ; 141"]
[null,null,"Disciplina",null,"591.2"]
[{"$nulls":4},"616.99"]
[{"$nulls":4},"616.992071"]
[null,null,"Soggetti",null,"Metastasis"]
[{"$nulls":4},"Internal medicine"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"Symposium on Metastasis, held at the Ciba Foundation, London, 19-21 April 1988. Editors: Gregory Bock (organizer) and Julie Whelan\" --P."]
[{"$nulls":4},"\"A Wiley-Interscience publication.\""]
[null,null,null,"Nota di bibliografia","Includes bibliographies and indexes."]
[null,null,"Nota di contenuto",null,"METASTASIS; Contents; Participants; Introduction; Tissue organizational stability and intercelIular invasion; Functional role of specific secreted and cell surface molecules in tumour cell invasion and metastasis; Adhesion mechanisms in embryogenesis and in cancer invasion and metastasis; The cell interaction sites of fibronectin in tumour metastasis; Oncogene induction of metastases; Adhesive properties of metastasizing tumour cells; Clonal changes in tumours during growth and progression evaluated by Southern gel analysis of random integrations of foreign DNA"]
[{"$nulls":4},"MolecuIar genetics of metastasisThe reversal of the metastatic phenotype by gene transfer; Inhibitors of collagenase IV and cell adhesion reduce the invasive activity of malignant tumour cells; Macrophage therapy of cancer metastasis; Clinical aspects of metastases; Index of contributors; Subject index"]
[null,null,null,"Sommario/riassunto","An international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal "]
[{"$nulls":4},"and abnormal cells, with emphasis on cell surface mechanisms--especially invasive processes--and inhibitors that might prevent metastasis. Also discusses determination of the metastatic genotype, the role of the immune system, and reduction of metastasis via liposome-activated macrophages."]