{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":2,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":45,"n_cols":5,"rows_kept":45,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[3,2,3,3],[7,2,7,3],[8,2,8,3],[9,2,9,3],[10,2,10,3],[13,2,13,3],[14,2,14,3],[18,2,18,3],[22,2,22,3],[22,4,22,5],[23,2,23,3],[23,4,23,5],[24,2,24,3],[25,2,25,3],[26,2,26,3],[27,2,27,3],[28,2,28,3],[29,2,29,3],[38,2,38,3],[39,2,39,3],[42,2,42,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910144093303321"]
[null,null,"Titolo",null,"Defining optimal immunotherapies for type 1 diabetes [[electronic resource] /] / [editors: Gregory Bock and Jamie Goode]"]
[null,null,"Pubbl/distr/stampa",null,"London, : Novartis Foundation, 2008"]
[null,null,"ISBN",null,"1-281-84052-1"]
[{"$nulls":4},"9786611840525"]
[{"$nulls":4},"0-470-69740-7"]
[{"$nulls":4},"0-470-69741-5"]
[null,null,"Descrizione fisica",null,"1 online resource (224 p.)"]
[null,null,"Collana",null,"Novartis Foundation symposium ; ; v. 292"]
[null,null,"Disciplina",null,"616.46206"]
[null,null,"Soggetti",null,"Diabetes - Immunotherapy"]
[{"$nulls":4},"Diabetes - Treatment"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Defining Optimal Immunotherapies for Type 1 Diabetes; Contents; Participants; Chair's introduction; Pancreatic pathology in type 1 diabetes in human; The b cell population in type 1 diabetes; Bone marrow expressing a diabetes resistance MHC class II allele: diabetes deviation by chronic immune stimulation; Resuscitating adaptive Tregs with combination therapies?; Cytotoxic T cell mechanisms of b cell destruction in non-obese diabetic mice; Type 1 diabetes: chronic progressive autoimmune disease; Current and past prevention and intervention trials in type 1 diabetes"]
[{"$nulls":4},"CD8 and cytotoxic T cells in type 1 diabetesGeneral discussion I; General discussion II; Genetic and therapeutic control of diabetogenic CD8+ T cells; General discussion III; Towards a curative therapy in type 1 diabetes: remission of autoimmunity, maintenance and augmentation of b cell mass; Immune markers of disease and therapeutic intervention in type 1 diabetes; Re-establishing immune tolerance in type 1 diabetes via regulatory T cells; Translating mucosal antigen based prevention of autoimmune diabetes to human; Closing remarks; Contributor index; Subject index"]
[null,null,null,"Sommario/riassunto","This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D).Brings together contributions from the leaders in the "]
[{"$nulls":4},"arena of clinical immunotherapy, not limited to the diabetes field exclusively, in order to delineate a road-map that would lead to future clinical trials.The book integrates information from human and animal studies.The book considers T1D within the broader context of autoimmune disease.The format contains several discussions, which address specific questions and provides"]
[null,"2.","Record Nr.",null,"UNINA9910407727803321"]
[null,null,"Titolo",null,"Promoting the Health and Well-Being of People with Learning Disabilities / / edited by Pauline Heslop, Crispin Hebron"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020"]
[null,null,"ISBN",null,"3-030-43488-5"]
[null,null,"Edizione",null,"[1st ed. 2020.]"]
[null,null,"Descrizione fisica",null,"1 online resource (159 pages)"]
[null,null,"Disciplina",null,"362.20425"]
[null,null,"Soggetti",null,"Intellectual disability - nursing"]
[{"$nulls":4},"Social service"]
[{"$nulls":4},"Learning Disabilities Nursing"]
[{"$nulls":4},"Social Work"]
[{"$nulls":4},"Trastorns de l'aprenentatge"]
[{"$nulls":4},"Infermeria psiquiàtrica"]
[{"$nulls":4},"Assistència psiquiàtrica"]
[{"$nulls":4},"Assistència sanitària"]
[{"$nulls":4},"Llibres electrònics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Chapter 1. Being happy and healthy -- Chapter 2. Communication -- Chapter 3. Behaviour -- Chapter 4. Decision-making -- Chapter 5. Access to health services -- Chapter 6. Providing holistic care -- Chapter 7. Psychotropic medication -- Chapter 8. Death and dying -- Chapter 9. Staying healthy -- Chapter 10. Sources of advice about our health or that of others."]
[null,null,null,"Sommario/riassunto","This textbook presents a practical guide for new and experienced health or social care staff, helping them promote the health and well-being of people with learning disabilities. Given the considerable demand for mandatory training on supporting people with learning disabilities, especially in England, the book provides a valuable resource for all training courses on working with people with learning disabilities. The chapters are co-written by practitioners and people with learning disabilities and their families, rooting the book in the lived experiences of those concerned. Topics covered include core elements of being happy and healthy, communication, changes in our behaviour when we are unwell, making decisions about our health, "]
[{"$nulls":4},"accessing health services, how we would want to be treated if we were unwell, the use of psychotropic medication, what a ‘good death’ would be, and how to keep ourselves healthy. In addition, the chapters include narrative examples concerning people with learning disabilities and their families, so as to highlight key points and share best-practice examples. The use of personal reflection is used to consider how we can ensure that people with learning disabilities receive care and support that matches what we would expect for ourselves. Core questions at the end of each chapter ask the reader to reflect on how the chapter content relates to their own work and how they will apply what they have learned. A consistent theme throughout the book is equality of opportunity for people with learning disabilities to achieve good health. There is now substantial evidence that people with learning disabilities have poorer health than the general population, are more likely to have multiple health needs, and can experience difficulties in having their illnesses diagnosed and treated promptly. This book aims to help those supporting people with learning disabilities to achieve more equal outcomes."]