{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":3,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":56,"n_cols":5,"rows_kept":56,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[2,4,2,5],[3,2,3,3],[4,2,4,3],[9,2,9,3],[10,2,10,3],[11,2,11,3],[13,2,13,3],[17,2,17,3],[18,2,18,3],[22,2,22,3],[28,2,28,3],[28,4,28,5],[29,2,29,3],[29,4,29,5],[30,2,30,3],[30,4,30,5],[31,2,31,3],[32,2,32,3],[33,2,33,3],[34,2,34,3],[35,2,35,3],[38,2,38,3],[39,2,39,3],[39,4,39,5],[40,2,40,3],[40,4,40,5],[41,2,41,3],[42,2,42,3],[47,2,47,3],[48,2,48,3],[49,2,49,3],[51,2,51,3],[52,2,52,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910144004603321"]
[null,null,"Autore",null,"Kandel Heinz G"]
[null,null,"Titolo",null,"Verfahrenstechnische Methoden in der Wirkstoffherstellung [[electronic resource] ] : Tipps und Tricks / / Heinz G. Kandel"]
[null,null,"Pubbl/distr/stampa",null,"Weinheim [Germany], : Wiley-VCH, 2006"]
[null,null,"ISBN",null,"3-527-66042-9"]
[{"$nulls":4},"1-280-66314-6"]
[{"$nulls":4},"9786613640079"]
[{"$nulls":4},"3-527-66096-8"]
[{"$nulls":4},"3-527-60780-3"]
[null,null,"Edizione",null,"[1. Aufl.]"]
[null,null,"Descrizione fisica",null,"1 online resource (202 p.)"]
[null,null,"Disciplina",null,"615.19"]
[{"$nulls":4},"615/.19"]
[null,null,"Soggetti",null,"Pharmaceutical industry"]
[{"$nulls":4},"Drugs - Design"]
[{"$nulls":4},"Drug factories"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Tedesco"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"Inkl. CD-ROM.\""]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Title Page; Inhaltsverzeichnis; Vorwort; 1 Einleitung; 2 Der Rohstoff: Blut, Blutplasma [1]; 3 Besondere Spezifitaumalten fuumalr die Verfahrenstechnik; 3.1 Molekuumallgroumalbe und Struktur; 3.2 Anzahl der Prozessstufen; 3.3 Analytik, Messmethoden; 3.4 Zulassungsproblematik; 4 Blutplasmafraktionierung; 4.1 Beschreibung des Prozesses; 4.1.1 Kryogewinnung; 4.1.2 Faumalllungsschritte; 4.1.3 Adsorptionsschritte; 4.1.4 Reinigung der Proteine, Bulkherstellung, Abfuumalllung, Gefriertrocknung; 4.2 Verfahrenstechnische Gesichtspunkte; 4.2.1 Behaumallter und Ruumalhrwerke"]
[{"$nulls":4},"4.2.1.1 Allgemeine Ausruumalstung, Spezifikation4.2.1.2 Funktionstypicals; 4.2.1.3 Ruumalhrwerke; 4.2.1.4 Spezielle Einsatzfaumallle fuumal r Behaumallter; 4.2.2 Fest-Fluumalssig-Trennung; 4.2.2.1 Separatoren, Zentrifugen; 4.2.2.2 Filter; 4.2.3 Pumpen; 4.2.3.1 Kreiselpumpe; 4.2.3.2 Kolbenpumpe und Membrankolbenpumpe; 4.2.3.3 Kreiskolbenpumpe; 4.2.3.4 Schlauchpumpe; 4.2.4 Rohrleitungen, Ventile, Verbindungstechnik; 4.2.4.1 Rohrleitungen; 4.2.4.2 Schweibverbindungen; 4.2.4.3 "]
[{"$nulls":4},"Verbindungstechnik; 4.2.4.4 Ventiltechnik; 4.2.4.5 Messtechnik; 4.2.5 Membrantrennverfahren [10, 11]"]
[{"$nulls":4},"6.5 Scale-up von Zentrifugen aus Laboroder Produktionslaumalufen6.6 Schubspannungen in Rohrleitungen; 6.7 Scale-up von Ultrafiltrationskassetten; 6.8 Scale-up von Filtern; 6.9 Berechnung der maximal moumalglichen Dosiergeschwindigkeiten von Aumalthanol bei der Faumalllung; 6.10 Schnelle Dimensionierung eines Behaumallters; 6.11 Instationaumalre Aufheizund Abkuumalhlvorgaumalnge in einem Ruumalhrbehaumallter; 6.12 Temperierung eines Behaumallters durch externen Produktkreislauf; 6.13 Temperierung eines Behaumallters mittels eines Waumalrmetraumalgerkreislaufes"]
[{"$nulls":4},"6.14 Waumalrmeverlust einer isolierten Rohrleitung"]
[null,null,null,"Sommario/riassunto","Bei der Herstellung von pharmakologischen Wirkstoffen kommen eine Vielzahl verfahrenstechnischer Grundoperationen zur Anwendung. Dies sind beispielsweise Zentrifugation, Filtration und Ultrafiltration, Chromatographie und Gefriertrocknung. Insbesondere zur Herstellung von Produkten aus Blutplasma gelten besondere Anforderungen wie Steril- und Reinraumtechnik und schonende Weiterverarbeitung. Das vorliegende Buch gibt einen praktischen Überblick über verfahrenstechnische Methoden und bewährte Lösungen in der pharmazeutischen Wirkstoffherstellung und beschreibt erstmals die Besonderheiten und ve"]
[null,"2.","Record Nr.",null,"UNINA9910144700703321"]
[null,null,"Autore",null,"Unsicker Klaus"]
[null,null,"Titolo",null,"Cell Signaling and Growth Factors in Development: From Molecules to Organogenesis"]
[null,null,"Pubbl/distr/stampa",null,"[Place of publication not identified], : John Wiley & Sons Incorporated, 2005"]
[null,null,"ISBN",null,"3-527-61968-2"]
[null,null,"Disciplina",null,"571.81"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,"Nota di contenuto",null,"Stem cells -- Germ cells -- Implantation and placentation -- Cell movements during early vertebrate morphogenesis -- Head induction -- Anterior-posterior patterning of the hindbrain: integrating boundaries and cell segregation with segment formation and identity -- Neurogenesis in the central nervous system -- Generating cell diversity -- The molecular basis of directional cell migration -- Cell dealth in organ development -- Dorso-ventral patterning of the vertebrate central nervous system -- Novel perspectives in research on the neural crest and its derivatives -- Eye development -- Mammalian inner ear development: of mice and man -- Limb development -- Skeletal development -- Musculature and growth factors -- Skin development -- Tooth development -- Gastrointestinal tract -- Cell signaling and growth factors in lung development -- Molecular genetics of liver and pancreas development -- Molecular networks in cardiac development -- Vasculogenesis -- Inductive signaling in kidney morphogenesis -- Molecular and cellular pathways for the morphogenesis of mouse sex organs."]
[null,"3.","Record Nr.",null,"UNINA9910795952103321"]
[null,null,"Titolo",null,"How to succeed in psychiatry [[electronic resource] ] : a guide to training and practice / / edited by Andrea Fiorillo, Iris Calliess, and Henning Sass"]
[null,null,"Pubbl/distr/stampa",null,"Chichester, West Sussex, : J. Wiley-Blackwell, 2012"]
[null,null,"ISBN",null,"1-119-95365-0"]
[{"$nulls":4},"1-119-96194-7"]
[{"$nulls":4},"9786613629500"]
[{"$nulls":4},"1-119-95366-9"]
[{"$nulls":4},"1-280-59966-9"]
[null,null,"Descrizione fisica",null,"1 online resource (325 pages)"]
[null,null,"Disciplina",null,"616.89"]
[null,null,"Soggetti",null,"Psychiatry - Practice"]
[{"$nulls":4},"Psychiatry - Vocational guidance"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Includes index."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]