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[null,"1.","Record Nr.",null,"UNINA9910143558203321"]
[null,null,"Autore",null,"Pintilie Melania"]
[null,null,"Titolo",null,"Competing risks [[electronic resource] ] : a practical perspective / / Melania Pintilie"]
[null,null,"Pubbl/distr/stampa",null,"Chichester, England ; ; Hoboken, NJ, : John Wiley & Sons, c2006"]
[null,null,"ISBN",null,"1-280-72222-3"]
[{"$nulls":4},"1-282-12386-6"]
[{"$nulls":4},"9786612123863"]
[{"$nulls":4},"9786610722228"]
[{"$nulls":4},"0-470-87070-2"]
[{"$nulls":4},"0-470-87069-9"]
[null,null,"Descrizione fisica",null,"1 online resource (242 p.)"]
[null,null,"Collana",null,"Statistics in practice"]
[null,null,"Disciplina",null,"519.2"]
[null,null,"Soggetti",null,"Competing risks"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. 209-213) and index."]
[null,null,"Nota di contenuto",null,"Competing Risks; Contents; Preface; Acknowledgements; 1 Introduction; 1.1 Historical notes; 1.2 Defining competing risks; 1.3 Use of the Kaplan-Meier method in the presence of competing risks; 1.4 Testing in the competing risk framework; 1.5 Sample size calculation; 1.6 Examples; 1.6.1 Tamoxifen trial; 1.6.2 Hypoxia study; 1.6.3 Follicular cell lymphoma study; 1.6.4 Bone marrow transplant study; 1.6.5 Hodgkin's disease study; 2 Survival - basic concepts; 2.1 Introduction; 2.2 Definitions and background formulae; 2.2.1 Introduction; 2.2.2 Basic mathematical formulae"]
[{"$nulls":4},"2.2.3 Common parametric distributions2.2.4 Censoring and assumptions; 2.3 Estimation and hypothesis testing; 2.3.1 Estimating the hazard and survivor functions; 2.3.2 Nonparametric testing: log-rank and Wilcoxon tests; 2.3.3 Proportional hazards model; 2.4 Software for survival analysis; 2.5 Closing remarks; 3 Competing risks - definitions; 3.1 Recognizing competing risks; 3.1.1 Practical approaches; 3.1.2 Common endpoints in medical research; 3.2 Two mathematical definitions; 3.2.1 Competing risks as bivariate random variable; 3.2.2 Competing risks as latent failure times"]
[{"$nulls":4},"3.3 Fundamental concepts3.3.1 Competing risks as bivariate random variable; 3.3.2 Competing risks as latent failure times; 3.3.3 Discussion "]
[{"$nulls":4},"of the two approaches; 3.4 Closing remarks; 4 Descriptive methods for competing risks data; 4.1 Product-limit estimator and competing risks; 4.2 Cumulative incidence function; 4.2.1 Heuristic estimation of the CIF; 4.2.2 Nonparametric maximum likelihood estimation of the CIF; 4.2.3 Calculating the CIF estimator; 4.2.4 Variance and confidence interval for the CIF estimator; 4.3 Software and examples; 4.3.1 Using R; 4.3.2 Using SAS; 4.4 Closing remarks"]
[{"$nulls":4},"5 Testing a covariate5.1 Introduction; 5.2 Testing a covariate; 5.2.1 Gray's method; 5.2.2 Pepe and Mori's method; 5.3 Software and examples; 5.3.1 Using R; 5.3.2 Using SAS; 5.4 Closing remarks; 6 Modelling in the presence of competing risks; 6.1 Introduction; 6.2 Modelling the hazard of the cumulative incidence function; 6.2.1 Theoretical details; 6.2.2 Model-based estimation of the CIF; 6.2.3 Using R; 6.3 Cox model and competing risks; 6.4 Checking the model assumptions; 6.4.1 Proportionality of the cause-specific hazards; 6.4.2 Proportionality of the hazards of the CIF"]
[{"$nulls":4},"6.4.3 Linearity assumption6.5 Closing remarks; 7 Calculating the power in the presence of competing risks; 7.1 Introduction; 7.2 Sample size calculation when competing risks are not present; 7.3 Calculating power in the presence of competing risks; 7.3.1 General formulae; 7.3.2 Comparing cause-specific hazards; 7.3.3 Comparing hazards of the subdistributions; 7.3.4 Probability of event when the exponential distribution is not a valid assumption; 7.4 Examples; 7.4.1 Introduction; 7.4.2 Comparing the cause-specific hazard; 7.4.3 Comparing the hazard of the subdistribution; 7.5 Closing remarks"]
[{"$nulls":4},"8 Other issues in competing risks"]
[null,null,null,"Sommario/riassunto","The need to understand, interpret and analyse competing risk data is key to many areas of science, particularly medical research. There is a real need for a book that presents an overview of methodology used in the interpretation and analysis of competing risks, with a focus on practical applications to medical problems, and incorporating modern techniques. This book fills that need by presenting the most up-to-date methodology, in a way that can be readily understood, and applied, by the practitioner."]