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[null,"1.","Record Nr.",null,"UNINA9910141229603321"]
[null,null,"Titolo",null,"Analysis of aggregates and particles in protein pharmaceuticals [[electronic resource] /] / edited by Hanns-Christian Mahler, Wim Jiskoot"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, N.J., : John Wiley & Sons, Inc., 2012"]
[null,null,"ISBN",null,"1-283-40104-5"]
[{"$nulls":4},"9786613401045"]
[{"$nulls":4},"1-118-15056-2"]
[{"$nulls":4},"1-118-15057-0"]
[{"$nulls":4},"1-118-15054-6"]
[null,null,"Descrizione fisica",null,"1 online resource (474 p.)"]
[null,null,"Disciplina",null,"615.1/9"]
[null,null,"Soggetti",null,"Pharmaceutical chemistry"]
[{"$nulls":4},"Protein drugs - Analysis"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"The critical need for robust assays for quantitation and characterization of aggregates of therapeutic proteins -- Separation based analytical methods for measuring protein aggregation -- Laser light scattering-based techniques used for the characterization of protein therapeutics -- Online detection methods and emerging techniques for soluble aggregates in protein pharmaceuticals -- Analytical methods to measure sub-visible particulates -- Detection of visible particles in parenteral products -- Characterization of aggregates and particles using emerging techniques -- Ultraviolet absorption spectroscopy -- Fluorescence spectroscopy to characterize protein aggregates and particles -- Infrared spectroscopy to characterize protein aggregates -- Raman microscopy for characterization of particles -- Microscopic methods for particle characterization in protein pharmaceuticals -- Comparison of methods for soluble aggregate detection and size characterization -- Protein purification and its relation to protein aggregation and particles -- Formulation development and its relation to protein aggregation and particles."]
[null,null,null,"Sommario/riassunto","This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to "]
[{"$nulls":4},"quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy."]
[null,"2.","Record Nr.",null,"UNICAMPANIAVAN00289339"]
[null,null,"Titolo",null,"Europa a confronto : innovazione, tecnologia, società / a cura di Antonio Ruberti"]
[null,null,"Pubbl/distr/stampa",null,"Roma ; Bari, : Laterza, 1990"]
[null,null,"ISBN",null,"978-88-420-3693-7"]
[null,null,"Descrizione fisica",null,"VI, 543 p. ; 22 cm"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]