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[null,"1.","Record Nr.",null,"UNINA9910141014803321"]
[null,null,"Titolo",null,"Pharmaceutical toxicology in practice [[electronic resource] ] : a guide for non-clinical development / / edited by Alberto Lodola, Jeanne Stadler"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, N.J., : John Wiley & Sons, c2011"]
[null,null,"ISBN",null,"0-470-92272-9"]
[{"$nulls":4},"1-283-07223-8"]
[{"$nulls":4},"9786613072238"]
[{"$nulls":4},"0-470-90991-9"]
[{"$nulls":4},"0-470-90990-0"]
[null,null,"Descrizione fisica",null,"1 online resource (268 p.)"]
[null,null,"Disciplina",null,"615/.7040724"]
[null,null,"Soggetti",null,"Drugs - Toxicity testing"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"The regulatory environment / Claudio Bernardi and Marco Brughera --Toxicological development : roles and responsibilities / Franck Chuzel and Bernard Ruty -- Contract research organizations / Maurice Cary -- Safety pharmacology / Claudio Arrigoni and Valeria Perego -- Formulations, impurities and toxicokinetics / Claude Charuel -- General toxicology / Alberto Lodola -- Genetic toxicology / Peggy Guzzie-Peck, Jennifer Sasaki, and Sandy Weiner -- Developmental and reproductive toxicology / Jeanne Stadler -- Data analysis, report writing and regulatory documentation / Monique Y. Wells -- Risk management / Alberto Lodola."]
[null,null,null,"Sommario/riassunto","This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in t"]