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[null,"1.","Record Nr.",null,"UNINA9910137119603321"]
[null,null,"Autore",null,"Wolfgang Christopher L."]
[null,null,"Titolo",null,"Cancer screening and genetics / / Christopher L. Wolfgang, MD, PhD"]
[null,null,"Pubbl/distr/stampa",null,"Philadelphia, Pennsylvania : , : Elsevier, , 2015"]
[{"$nulls":4},"©2015"]
[null,null,"ISBN",null,"0-323-40107-4"]
[null,null,"Descrizione fisica",null,"1 online resource (244 p.)"]
[null,null,"Collana",null,"Surgical Clinics of North America, , 0039-6109 ; ; Volume 95, Number 5"]
[null,null,"Disciplina",null,"616.994042"]
[null,null,"Soggetti",null,"Cancer - Genetic aspects"]
[{"$nulls":4},"Cancer - Early detection"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"October 2015.\""]
[null,null,null,"Nota di bibliografia","Includes bibliographical references at the end of each chapters and index."]
[null,null,"Nota di contenuto",null,"Cover image; Title page; Table of Contents; Copyright; Contributors; Consulting Editor; Editor; Authors; Forthcoming Issues; Forthcoming Issues; Recent Issues; Foreword: Cancer Screening and Genomics; Preface; Background; Cancer Genetics and Implications for Clinical Management; Key points; Introduction; Understanding the cancer genome landscape and translating advances for therapeutic gain; Driver versus passenger mutations; Mutational signatures in cancer; Rationale of genotype-guided medicine; Managing tumor heterogeneity and resistance to targeted therapy"]
[{"$nulls":4},"Advancing molecular phenotype-guided therapy in pancreatic cancerIndividualized therapy initiatives; Inherited susceptibility of cancer in the era of next-generation sequencing; Exceptional responders; Summary; The Triple-Code Model for Pancreatic Cancer; Key points; Cross talk between genetics and epigenetics as a promising paradigm in pancreatology; Mechanistic basis of epigenetics: the nucleosome; Marking the genome by methylation; Epigenetic regulation by noncoding RNAs; Shaping gene expression through nuclear architecture"]
[{"$nulls":4},"Epigenetics opens a new era for pancreatic cancer markers and novel therapeutic modalitiesSummary; Principles of Cancer Screening; Key points; Introduction; Performance characteristics of screening tests; Measures of screening benefit; Common biases in assessing the benefits of screening; Harms of screening; Cost-effectiveness and targeted screening; Current recommended cancer screening tests in "]
[{"$nulls":4},"North America; Screening and Early Detection: Specific Diseases; Lung Cancer Screening; Key points; Introduction; Risks and harms of lung cancer screening; Practice of lung cancer screening; Summary"]
[{"$nulls":4},"Colorectal Cancer ScreeningKey points; Introduction: extent of the disease; Screening techniques and options; Clinical outcomes; Complications and concerns; Summary; Breast Cancer Screening; Key points; Introduction; Screening techniques and options; Personalized breast cancer screening; Complications and concerns; Summary; Screening for Viral Hepatitis and Hepatocellular Cancer; Key points; Screening for hepatitis B virus infection; Screening for hepatitis C virus infection; Diagnosing other viral hepatitides; Screening for hepatocellular carcinoma"]
[{"$nulls":4},"When to obtain a liver biopsy to diagnose hepatocellular carcinomaProstate Cancer Screening and the Associated Controversy; Key points; Introduction; Screening techniques and options; Clinical outcomes; Complications and concerns; Summary; Screening for Pancreatic Cancer; Key points; Introduction; How early does pancreatic cancer have to be detected for cure?; Target lesions; Who is at risk of developing pancreatic cancer? Who should be screened?; How should suspected lesions be managed?; Screening and Early Detection of Gastric Cancer; Key points"]
[{"$nulls":4},"Gastric cancer epidemiology: mortality, incidence between east and west"]