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[null,"1.","Record Nr.",null,"UNINA9910137091903321"]
[null,null,"Autore",null,"Martin Herrmann"]
[null,null,"Titolo",null,"Chronic inflammation in conditions associated with a deficient clearance of dying and dead cells, their remnants, and intracellular constituents [[electronic resource] /] / edited by  Luis Enrique Muñoz, Christian Berens, Kirsten Lauber [and 2 others]"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2015"]
[{"$nulls":4},"Lausanne, Switzerland : , : Frontiers Media SA, , [2015]"]
[{"$nulls":4},"©2015"]
[null,null,"Descrizione fisica",null,"1 online resource (73 pages) : illustrations; digital, PDF file(s)"]
[null,null,"Collana",null,"Frontiers research topics"]
[null,null,"Soggetti",null,"Immunology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Published in Frontiers in Immunology."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,null,"Sommario/riassunto","In multicellular organisms, states with a high degree of tissue turnover like embryogenesis, development, and adult tissue homeostasis need an instantaneous, tightly regulated and immunologically silent clearance of these dying cells to ensure appropriate development of the embryo and adult tissue remodelling. The proper and swift clearance of apoptotic cells is essential to prevent cellular leakage of damage associated molecular patterns (DAMPs) which would lead to the stimulation of inflammatory cytokine responses. In addition to the clearance of apoptotic cells (efferocytosis), backup mechanisms are required to cope with DAMPs (HMGB-1, DNA, RNA, S100 molecules, ATP and adenosine) and other intracellular material (uric acid, intracellular proteins and their aggregates) released from cells, that were not properly cleared and have entered the stage of secondary necrosis. Furthermore, under certain pathologic conditions (e.g. gout, cancer, diabetes) non-apoptotic cell death may transiently occur (NETosis, necroptosis, pyroptosis) which generates material that also has to be cleared to avoid overloading tissues with non-functional cellular waste. Efficient efferocytosis is therefore indispensable for normal tissue turnover and homeostasis. The characterization of various signalling pathways that regulate this complex and evolutionary conserved process has shed light on new pathogenetic mechanisms of "]
[{"$nulls":4},"many diseases. Impaired clearance promotes initiation of autoimmunity as well as the perpetuation of chronic inflammation, but may also foster anti-tumor immunity under certain microenvironmental conditions. Immunological tolerance is continuously being challenged by the presence of post-apoptotic remnants in peripheral lymphoid tissues. Besides the autoimmune phenotype of chronic inflammatory rheumatoid disorders a plethora of pathologies have been associated with defects in genes involved in clearance, e.g. atherosclerosis, cancer, gout, diabetes, some forms of blindness, neuropathy, schizophrenia and Alzheimer’s disease."]
[null,"2.","Record Nr.",null,"UNINA9910773679503321"]
[null,null,"Titolo",null,"Slovakia: Legislative Process"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"3.","Record Nr.",null,"UNINA9910778638203321"]
[null,null,"Autore",null,"Charlton James I."]
[null,null,"Titolo",null,"Nothing about us without us : disability oppression and empowerment / / James I. Charlton"]
[null,null,"Pubbl/distr/stampa",null,"Berkeley, CA : , : University of California Press, , [1998]"]
[{"$nulls":4},"©1998"]
[null,null,"ISBN",null,"1-280-09047-2"]
[{"$nulls":4},"9786613520357"]
[{"$nulls":4},"0-520-92544-0"]
[{"$nulls":4},"0-585-04779-0"]
[null,null,"Descrizione fisica",null,"1 online resource (215 p.)"]
[null,null,"Disciplina",null,"323.3"]
[null,null,"Soggetti",null,"People with disabilities - Civil rights"]
[{"$nulls":4},"People with disabilities - Social conditions"]
[{"$nulls":4},"Discrimination against people with disabilities"]
[{"$nulls":4},"Sociology of disability"]
[{"$nulls":4},"Stigma (Social psychology)"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. [179]-194) and index."]
[null,null,"Nota di contenuto",null,"Front matter -- Contents -- The Argument -- Acknowledgments -- People Interviewed -- Part I. Introduction -- Part II. Disability Oppression and Everyday Life -- Part III. Empowerment and Organization -- Part IV. Conclusion -- Notes -- Bibliography -- Index"]
[null,null,null,"Sommario/riassunto","James Charlton has produced a ringing indictment of disability oppression, which, he says, is rooted in degradation, dependency, and powerlessness and is experienced in some form by five hundred million persons throughout the world who have physical, sensory, cognitive, or developmental disabilities. Nothing About Us Without Us is the first book in the literature on disability to provide a theoretical overview of disability oppression that shows its similarities to, and differences from, racism, sexism, and colonialism. Charlton's analysis is illuminated by interviews he conducted over a ten-year period with disability rights activists throughout the Third World, Europe, and the United States. Charlton finds an antidote for dependency and powerlessness in the resistance to disability oppression that is emerging worldwide. His interviews contain striking stories of self-"]
[{"$nulls":4},"reliance and empowerment evoking the new consciousness of disability rights activists. As a latecomer among the world's liberation movements, the disability rights movement will gain visibility and momentum from Charlton's elucidation of its history and its political philosophy of self-determination, which is captured in the title of his book. Nothing About Us Without Us expresses the conviction of people with disabilities that they know what is best for them. Charlton's combination of personal involvement and theoretical awareness assures greater understanding of the disability rights movement."]
[null,"4.","Record Nr.",null,"UNISANNIOUMC0059835"]
[null,null,"Titolo",null,"2: Personalità autoritaria e interviste cliniche / T. W. Adorno ... [et al.] ; in collaborazione con B. Aron, M. Hertz Levinson, W. R. Morrow"]
[null,null,"Pubbl/distr/stampa",null,"Milano, : Edizioni di Comunità, 1982"]
[null,null,"Descrizione fisica",null,"VIII, 286 p. ; 20 cm."]
[null,null,"Disciplina",null,"303.385"]
[null,null,"Collocazione",null,"POZZO LIB.F. SANTI                180"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]