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[null,"1.","Record Nr.",null,"UNINA9910482999703321"]
[null,null,"Titolo",null,"2019 press conference records of Ministry of Ecology and Environment, the People's Republic of China / / Ministry of Ecology and Environment"]
[null,null,"Pubbl/distr/stampa",null,"Singapore ; ; Beijing, China : , : Springer : , : China Environment Publishing Group Co., Ltd., , [2021]"]
[{"$nulls":4},"©2021"]
[null,null,"ISBN",null,"981-334-810-0"]
[null,null,"Edizione",null,"[1st ed. 2021.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XVII, 380 p. 53 illus., 51 illus. in color.)"]
[null,null,"Disciplina",null,"363.705"]
[null,null,"Soggetti",null,"Environmental policy - China"]
[{"$nulls":4},"Environmental management"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Chapter 1. Record of the press conference for the 70th anniversary of the founding of New China -- Chapter 2. Record of the press conference of the State Council Office -- Chapter 3. Routine Press Conference Record."]
[null,null,null,"Sommario/riassunto","This book introduces the press release work carried out by Ministry of Ecology and Environment of the People’s Republic of China in 2019. It is divided into four parts, each arranged chronologically. The first part contains the records of Li Ganjie, Minister of the Ministry of Ecology and Environment, who attended the press conference on \"Promoting Ecological Civilization and Building a Beautiful China\". The second part contains the records of Minister Li Ganjie's attendance at the press conference of the National People's Congress and the Chinese Political Consultative Conference as well as the \"Minister channel\". The third part contains the records of four press conferences on ecological and environmental protection held by the State Council Information Office of the People's Republic of China. The fourth part contains the records of 12 regular press conferences held by the Ministry of Ecology and Environment."]
[null,"2.","Record Nr.",null,"UNINA9910136407603321"]
[null,null,"Autore",null,"Jan Trost Jorgensen"]
[null,null,"Titolo",null,"Drug-diagnostics co-development in oncology [[electronic resource] /] / topic editor Jan Trøst Jørgensen"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2014"]
[{"$nulls":4},"France : , : Frontiers Media SA, , 2014"]
[null,null,"ISBN",null,"9782889193325 (ebook)"]
[null,null,"Descrizione fisica",null,"1 online resource (111 pages) : colour illustrations, charts"]
[null,null,"Collana",null,"Frontiers Research Topics"]
[null,null,"Disciplina",null,"615.1/9"]
[null,null,"Soggetti",null,"Oncology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,null,"Sommario/riassunto","The idea of combining drugs and diagnostics in oncology is not new. When the selective estrogen receptor modulator tamoxifen was developed in the 1970’s for the treatment of breast cancer a positive correlation between receptor status and treatment outcome was found. As a result of this research, it was suggested to use the estrogen-receptor assay as a diagnostic test for selection of patients for tamoxifen treatment. Despite this suggestion was put forward nearly 40 years ago the adaptation of the drug-diagnostic co-development model has been relatively slow and it is only within the last decade that it has gained more widespread acceptance. The parallel development of the monoclonal antibody trastuzumab (Herceptin®, Roche/Genentech) and the immunohistochemistry assay for HER2 protein overexpression (HercepTest™, Dako) seems to have served as an inspiration to a number of stakeholders such as pharma and diagnostic companies, regulatory agencies, and academia. In recent years we have seen an increasing number of oncology drug development projects that have taken advantage of the drug-diagnostic co-development model, as outline below. Most of the new targeted anti-cancer drugs that have been introduced in recent years, such as BRAF-, ALK-, EGFR- and HER2-inhibitors, are more or less all a product of the drugdiagnostic co-development model. These drugs have shown remarkable high response rates in selected groups of patients within cancer diseases with great unmet medical needs."]