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[null,"1.","Record Nr.",null,"UNISA990003153990203316"]
[null,null,"Autore",null,"GUERRESCHI, Giuseppe"]
[null,null,"Titolo",null,"Guerreschi : dipinti / introduzione di Luigi Carluccio Enrico Crispolti"]
[null,null,"Pubbl/distr/stampa",null,"Roma : Ed. Fante di Spade, [s.d.]"]
[null,null,"Descrizione fisica",null,"1 v. ; 24 cm"]
[null,null,"Disciplina",null,"759.5"]
[null,null,"Soggetti",null,"Guerreschi, Giuseppe Opere"]
[null,null,"Collocazione",null,"V F CAR"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910298298203321"]
[null,null,"Autore",null,"Fernández Stigliano Ariel"]
[null,null,"Titolo",null,"Biomolecular Interfaces : Interactions, Functions and Drug Design / / by Ariel Fernández Stigliano"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015"]
[null,null,"ISBN",null,"3-319-16850-9"]
[null,null,"Edizione",null,"[1st ed. 2015.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XIX, 372 p. 145 illus., 86 illus. in color.)"]
[null,null,"Disciplina",null,"574.19283"]
[null,null,"Soggetti",null,"Proteins"]
[{"$nulls":4},"Biological transport"]
[{"$nulls":4},"Cell membranes"]
[{"$nulls":4},"Medicine - Research"]
[{"$nulls":4},"Biology - Research"]
[{"$nulls":4},"Pharmaceutical chemistry"]
[{"$nulls":4},"Biophysics"]
[{"$nulls":4},"Protein Biochemistry"]
[{"$nulls":4},"Membrane Trafficking"]
[{"$nulls":4},"Biomedical Research"]
[{"$nulls":4},"Pharmaceutics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,"Nota di contenuto",null,"The Aqueous Interface of a Soluble Protein or the Birth of Epistructural Biology -- Electrostatic Exploration of Biomolecular Interfaces: The Chemical Function of Interfacial Water -- Semiempirical Solution to the Protein Folding Problem Through a Combination of Structural and Epistructural Approaches -- Packing Defects and Protein Hydration: Dynamics of the Aqueous Interface -- Proteins in the Order-Disorder Twilight: Unstable Interfaces Promote Protein Aggregation -- Evolution of Protein Structure Degradation and Lessons for the Drug Designer -- Chemical Functionality of the Aqueous Interface in Soluble Proteins -- The Biomolecular Interface as a Selectivity Filter for Drug-Based Targeted Therapy -- Wrapping-Based Re-Engineering of an Anticancer Drug to Make it Safer -- Biomolecular Interfaces Provide Universal Markers for Drug Specificity and Personalized Medicine -- Controlling Induced Folding Through Wrapping Drug Design -- Wrapping Drug "]
[{"$nulls":4},"Combinations for Therapeutic Editing of Side Effects: Systems Biology Meets Wrapping Technology -- Multi-Target Control of Drug Impact: A Therapeutic Imperative in Cancer Systems Biology -- Engineering Therapeutic Alignments between Immune Response and Molecularly Targeted Cancer Treatment -- High-Level Quantum Chemistry Empowers the Wrapping Technology for Drug Design -- Epilogue -- Appendix 1. Code for Dehydron Identification -- Appendix 2. Solutions of Problems."]
[null,null,null,"Sommario/riassunto","The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and biomolecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering."]
[null,"3.","Record Nr.",null,"UNINA9910136358903321"]
[null,null,"Autore",null,"Thierry Dubost (dir.)"]
[null,null,"Titolo",null,"L'adaptation théâtrale en Irlande de 1970 à 2007"]
[null,null,"Pubbl/distr/stampa",null,"Presses universitaires de Caen, 2010"]
[{"$nulls":4},"[Place of publication not identified], : Presses universitaires de Caen, 2010"]
[null,null,"ISBN",null,"2-84133-462-7"]
[null,null,"Descrizione fisica",null,"1 online resource (334 pages)"]
[null,null,"Collana",null,"Quæstiones"]
[null,null,"Soggetti",null,"English"]
[{"$nulls":4},"Languages & Literatures"]
[{"$nulls":4},"English Literature"]
[null,null,"Lingua di pubblicazione",null,"Francese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,null,"Sommario/riassunto","Ce livre, consacré à l’adaptation théâtrale en Irlande de 1970 à 2007, s’attache aux réécritures dramatiques qui virent le jour en des temps marqués par une effervescence notable sur le plan des adaptations. Le bornage temporel initial s’explique par une renaissance théâtrale en Irlande à cette époque, renouveau marqué notamment par l’apparition de dramaturges majeurs, tels Brian Friel, Tom Murphy ou Thomas Kilroy. Les travaux rassemblés dans cet ouvrage s’efforcent de poser un regard neuf sur l’adaptation en Irlande, et de mettre à jour quelques singularités révélatrices du paysage théâtral irlandais contemporain. Loin d’être une histoire de l’adaptation, les diverses contributions de ce livre interrogent de façon variée la manière dont l’adaptation a apposé sa marque sur le théâtre irlandais depuis les années soixante-dix."]