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[null,"1.","Record Nr.",null,"UNINA9910136287303321"]
[null,null,"Autore",null,"Tomoyuki Miura"]
[null,null,"Titolo",null,"Animal model studies on viral infections [[electronic resource] /] / Topic editors: Akio Adachi and Tomoyuki Miura"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2015"]
[{"$nulls":4},"[Place of publication not identified] : , : Frontiers Media SA, , 2015"]
[{"$nulls":4},"©2007-2015"]
[null,null,"Descrizione fisica",null,"1 online resource (173 pages) : illustrations; digital, PDF file(s)"]
[null,null,"Collana",null,"Frontiers research topics"]
[{"$nulls":4},"Frontiers in microbiology"]
[null,null,"Soggetti",null,"Microbiology"]
[{"$nulls":4},"Virus diseases - Pathogenesis"]
[{"$nulls":4},"Virology - Research"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Animal model studies on viral infections --Animal models for human Herpesvirus 6 infection --Animal models for Ebola and Marburg virus infections --Hepatitis C virus infection and related liver disease: the quest for the best animal model --Can non-human primates serve as models for investigating Dengue disease pathogenesis? --A transgenic mouse model of human T cell Leukemia virus type-1 associated diseases --Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus --Macaques as model hosts for studies of HIV-1 infection --Macaque-tropic Human Immunodeficiency Virus type 1: breaking out of the host restriction factors --Genetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic Simian-Human Immunodeficiency Virus infection --A novel but simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4⁺ T cells in the hu-PBL SCID mice --Growth potentials of CCR5-Tropic/CXCR4-Tropic HIV-1mt clones in macaque cells --Sensitive detection of measles virus infection in the blood and tissues of humanized mouse by one-step quantitative RT-PCR --Quantification of viral infection dynamics in animal experiments --Transgenic expression of the human LEDGF/p75 gene relieves the species barrier "]
[{"$nulls":4},"against HIV-1 infection in mouse cells --Increased infectivity in human cells and resistant to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail --Natural infection of murine novovirus in conventional and specific pathogen free laboratory mice --HPV18 E1̂ˆ̂E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins."]
[null,null,null,"Sommario/riassunto","Understanding viral replication and pathogenicity properties in infected individuals is a major mission of animal virology. Animal models are essential to analyze the in vivo viral characteristics and to develop countermeasures against viruses. To fight against a wide variety of viruses, basic studies with specific and/ or common approaches are required. This Research Topic collects articles that describe studies on numerous virus species at various stages toward animal experiments: (i) description/evaluation/ new challenges of animal model studies; (ii) experimental material/methods for animal model studies; (iii) observations for upcoming animal model studies. Numbers of DNA and RNA viruses such as HHV-6, HPV, Ebola virus, HCV, dengue virus, HTLV-1, HIV-1, SIV, and measles virus are covered by this special issue consisting of original research, methods, review, mini-review, and opinion articles. All readers would understand, we believe and hope, that animal model studies are critical for current virology as always."]
[null,"2.","Record Nr.",null,"UNINA9910674345103321"]
[null,null,"Autore",null,"El-Awad Ziad"]
[null,null,"Titolo",null,"Academic Spin-offs : The Role of Routinized Behaviours in New Venture Success / / by Ziad El-Awad"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer International Publishing : , : Imprint : Palgrave Macmillan, , 2023"]
[null,null,"ISBN",null,"9783031222849"]
[{"$nulls":4},"9783031222832"]
[null,null,"Edizione",null,"[1st ed. 2023.]"]
[null,null,"Descrizione fisica",null,"1 online resource (159 pages) : illustrations"]
[null,null,"Disciplina",null,"658.421"]
[null,null,"Soggetti",null,"New business enterprises"]
[{"$nulls":4},"Venture capital"]
[{"$nulls":4},"Entrepreneurship"]
[{"$nulls":4},"Start-Ups and Venture Capital"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (pages 137-146) and index."]
[null,null,"Nota di contenuto",null,"Chapter one: Academic spin-offs and their role in society -- Chapter two: Routinizing behaviors in academic spin-offs -- Chapter three: Routinizing behaviors as a multilevel learning process -- Chapter four: Routines and the critical role of the venture team -- Chapter five: Routines for efficiency or change! -- Chapter six: learnings and implications for your business."]
[null,null,null,"Sommario/riassunto","This book discusses the importance of developing routinized behaviours in new venture development, explicitly highlighting the unique challenges that academic spinoffs face in this vital step towards successful business creation. During the early development stage, new ventures are informally established and have few routines that inform organizational performance. However, the process of new venture development is characterized by high ambiguity; for example, entrepreneurs have to deal with ill-defined technologies that are only vaguely understood or delineated. They also need to gradually make sense of the connections between technological functions, customer preferences and market structures. At the same time, during the early stage of new start-ups, experiences tend to be personal, embodied in specific individuals, such as the founder or founding team. Benefiting from these experiences and developing successful businesses that can exist independently of these individuals requires that these experiences "]
[{"$nulls":4},"become embedded in the form of routines. Presenting primary and empirical research, the author delivers a framework for the routinization of behaviours, demonstrating the challenges and opportunities that can intervene in this process. Finally, the author brings together implications that academics and practitioners can take and apply in their own ventures. Ziad El-Awad is a researcher at Sten K Johnson Centre for Entrepreneurship- Lund university. His research explores the routinisation of task work in new ventures and the role that entrepreneurial ecosystems play in supporting new ventures' development. In addition, his research unpacks enterprising activities in and around entrepreneurial ecosystems and identifies policies and economic implications of such activities."]