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[null,"1.","Record Nr.",null,"UNINA9910131531803321"]
[null,null,"Autore",null,"Alex Alexander A."]
[null,null,"Titolo",null,"Attrition in the pharmaceutical industry : reasons, implications, and pathways forward / / edited by Alexander Alex, C. John Harris, Dennis A. Smith"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, New Jersey : , : Wiley, , 2016"]
[{"$nulls":4},"©2016"]
[null,null,"ISBN",null,"1-118-91434-1"]
[{"$nulls":4},"1-118-81958-6"]
[{"$nulls":4},"1-118-81944-6"]
[null,null,"Descrizione fisica",null,"1 online resource (373 p.)"]
[null,null,"Disciplina",null,"615.1068/5"]
[null,null,"Soggetti",null,"Pharmaceutical industry - Management"]
[{"$nulls":4},"Pharmaceutical industry - Capital productivity"]
[{"$nulls":4},"Industrial efficiency"]
[{"$nulls":4},"Drug development"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Includes index."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Attrition in drug discovery and development / Scott Boyer, Clive Brealey and Andrew M. Davis -- Compound attrition at the pre-clinical phase / Cornelis E.C.A. Hop -- Attrition in phase I / Dennis A. Smith and Thomas A. Baillie -- Compound attrition in phase II/III / Alexander Alex, C. John Harris, Wilma W. Keighley and Dennis A. Smith -- Post-marketing attrition / Dennis A. Smith -- Influence of the regulatory environment on attrition / Robert T. Clay -- Experimental screening strategies to reduce attrition risk / Marie-Claire Peakman, Matthew Troutman, Rose Gonzales and Anne Schmidt -- Medicinal chemistry strategies to prevent compound attrition / J. Richard Morphy -- Influence of phenotypic and target-based screening strategies on compound attrition and project choice / Andrew Bell, Wolfgang Fecke and Christine Williams -- In silico approaches to address compound attrition / Peter Gedeck, Christian Kramer, Richard Lewis -- Current and future strategies for improving drug discovery efficiency / Peter Mbugua Njogu and Kelly Chibale -- Impact of investment strategies, organizational structure and corporate environment on attrition, and future investment strategies to reduce attrition / Geoff Lawton."]