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[null,"1.","Record Nr.",null,"UNINA990000994740403321"]
[null,null,"Autore",null,"Frajese, Attilio <1902-1986>"]
[null,null,"Titolo",null,"Galileo matematico / Attilio Frajese"]
[null,null,"Pubbl/distr/stampa",null,"Roma : Studium, 1964"]
[null,null,"Descrizione fisica",null,"206 p. ; 17 cm"]
[null,null,"Collana",null,"Universale Studium ; 96"]
[null,null,"Disciplina",null,"509"]
[null,null,"Locazione",null,"FLFBC"]
[{"$nulls":4},"FI1"]
[null,null,"Collocazione",null,"YI 24 96"]
[{"$nulls":4},"6B-075"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910131471703321"]
[null,null,"Titolo",null,"The treatment of epilepsy / / edited by Simon Shorvon, Emilio Perucca, Jerome Engel, Jr. ; contributors, Patrick Adjei [and one hundred thirty others]"]
[null,null,"Pubbl/distr/stampa",null,"Chichester, England : , : Wiley Blackwell, , 2016"]
[{"$nulls":4},"©2016"]
[null,null,"ISBN",null,"1-118-93697-3"]
[{"$nulls":4},"1-118-93699-X"]
[{"$nulls":4},"1-118-93698-1"]
[null,null,"Edizione",null,"[Fourth edition.]"]
[null,null,"Descrizione fisica",null,"1 online resource (2765 p.)"]
[null,null,"Disciplina",null,"617.481"]
[null,null,"Soggetti",null,"Epilepsy - Surgery"]
[{"$nulls":4},"Anticonvulsants - Therapeutic use"]
[{"$nulls":4},"Epilepsy - Chemotherapy"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Title page; Copyright; List of Contributors; Preface to the Fourth Edition; Preface to the First Edition; Historical Introduction The Drug Treatment of Epilepsy from 1857 to 2015; Commentary; Acknowledgement; References; Section I Introduction; 1 Definition (Terminology) and Classification in Epilepsy: A Historical Survey and Current Formulation, with Special Reference to the ILAE; Definition; Classification; The future of classification schemes of epilepsy; Definition; Definition and classification - status epilepticus; Afterthought; Acknowledgement; References"]
[{"$nulls":4},"2 Differential Diagnosis of EpilepsyIntroduction; General approach to the diagnosis of episodic disturbances; Syncope; Non-epileptic seizures; Panic disorder; Migraine; Sleep disorders; Vertigo; Movement disorders; Cerebral ischaemia; Endocrine and metabolic abnormalities; Transient global amnesia; References; 3 Mechanisms of Epileptogenesis; Membrane ion channels; Membrane ion channels as targets for antibodies in acquired autoimmune disorders; Network and system involvement in epileptogenesis; Epileptogenesis as a process; New targets for antiepileptic and antiepileptogenic strategies"]
[{"$nulls":4},"ConclusionsReferences; 4 Antiepileptic Drug Discovery; Characteristics of the ideal model system; The current era of AED discovery; "]
[{"$nulls":4},"Anticonvulsant Screening Program; Early identification of antiepileptic activity; MES, scPTZ and 6-Hz tests; Differentiation of anticonvulsant activity; Pharmacological profile and potential clinical utility; Pharmacoresistant seizure models; Therapeutic index and toxicity assessment; Aetiologically relevant model systems; Beyond the seizure; Antiepileptogenesis and disease modification (see also Chapter 8); Conclusions; Acknowledgement; References"]
[{"$nulls":4},"5 Antiepileptic Drug DevelopmentIntroduction; Overview on clinical studies and trials for drug development; Opportunities for developing better antiseizure AEDs; Development of epilepsy drugs beyond suppressing seizures; Conclusions; Acknowledgements; References; 6 Mechanisms of Antiepileptic Drug Action; Main targets; Other targets; References; 7 Mechanisms of Drug Resistance and Tolerance; Introduction; The concept of drug resistance in epilepsy; Disease-related mechanisms of drug resistance in epilepsy; Drug-related mechanisms of drug resistance in epilepsy"]
[{"$nulls":4},"Pharmacogenetic mechanisms of drug resistance in epilepsyProof-of-concept of drug resistance hypotheses; Conclusions; References; 8 Epilepsy Biomarkers; Introduction; Need for biomarkers; Mechanisms of epilepsy; Potential biomarkers; Research to identify biomarkers; Acknowledgements; References; Section II Principles of Medical Management; 9 General Principles of Medical Management; Aims of treatment; When should treatment be started?; Initiation of treatment and dose optimization; Assessing clinical response; What next when the initial treatment fails? - monotherapy and combination therapy"]
[{"$nulls":4},"How long should treatment be continued?"]