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[null,"1.","Record Nr.",null,"UNINA990004093820403321"]
[null,null,"Autore",null,"Slataper, Scipio <1888-1915>"]
[null,null,"Titolo",null,"Ibsen / Scipio Slataper"]
[null,null,"Pubbl/distr/stampa",null,"Firenze : Sansoni, 1944"]
[null,null,"Descrizione fisica",null,"365 p. ; 21 cm"]
[null,null,"Collana",null,"Biblioteca sansoniana critica ; 7"]
[null,null,"Disciplina",null,"839.8226"]
[null,null,"Locazione",null,"FLFBC"]
[null,null,"Collocazione",null,"839.8226 IBSEN/S 2 A"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910819754603321"]
[null,null,"Titolo",null,"Antiplatelet therapy in cardiovascular disease / / edited by Ron Waksman, Paul A. Gurbel, Michael A. Gaglia, Jr"]
[null,null,"Pubbl/distr/stampa",null,"Chichester, West Sussex, United Kingdom : , : John Wiley & Sons, , 2014"]
[{"$nulls":4},"©2014"]
[null,null,"ISBN",null,"1-118-49402-4"]
[{"$nulls":4},"1-118-49398-2"]
[{"$nulls":4},"1-118-49401-6"]
[null,null,"Descrizione fisica",null,"1 online resource (349 p.)"]
[null,null,"Disciplina",null,"616.1/061"]
[null,null,"Soggetti",null,"Cardiovascular system - Diseases"]
[{"$nulls":4},"Cardiovascular system - Diseases - Prevention"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Antiplatelet Therapy in Cardiovascular Disease; Copyright; Contents; List of Contributors; Foreword; Preface; Section I Platelet Biology and Pathophysiology; 1 Platelet Pathophysiology and its Role in Thrombosis; Role of platelets during initiation of atherosclerosis and plaque formation; Role of platelets in thrombosis; References; 2 Platelet Receptors and Drug Targets: COX-1; Structure, expression, and catalytic activity of platelet COX-1; Functional role of platelet COX -1; Genetic polymorphisms of COX-1 and COX-2 expression in platelets"]
[{"$nulls":4},"Platelet COX-1 as a target for antithrombotic therapyInteraction between aspirin and naNSAIDs at the level of platelet COX-1; In vitro and in vivo evidence for aspirin/naNSAID interaction; Concluding remarks; References; 3 Platelet Receptors and Drug Targets: P2Y12; P2 receptors; Roles of adenine nucleotides in platelet function; P2Y12; Conclusions; References; 4 Platelet Receptors and Drug Targets: GP IIb/IIIa; Introduction; Biology of the receptor; Glycoprotein IIb/IIIa receptor in platelet physiology; Platelet aggregation phase; \"Inside-out\" and \"outside-in\" GPIIb/IIIa signaling phenomenon"]
[{"$nulls":4},"Glycoprotein IIb/IIIa receptor and thrombus formationGlycoprotein IIb/IIIa receptor antagonists; Intravenous versus oral preparations: clinical aspects; Acknowledgment; References; 5 Platelet Receptors and Drug Targets: PAR1, Collagen, vWF, Thromboxane, and Other Novel Targets; Introduction; Protease-activated receptor 1 (PAR1); References; "]
[{"$nulls":4},"6 Role of Inflammation and Hypercoagulability in Thrombosis; References; Section II Platelet Function Tests; 7 Light Transmission Aggregometry; Technique; References; 8 Vasodilator-Stimulated Phosphoprotein (VASP) Assay; Introduction; The VASP index assay"]
[{"$nulls":4},"VASP index and clinical eventsAlteration of antiplatelet therapy based on the VASP index; VASP index and new oral antiplatelet agents; Conclusions; References; 9 VerifyNow P2Y12 and Plateletworks Assays; Introduction; Verifynow P2Y12; Plateletworks; Validity of the test in measuring antiplatelet effect and its association with clinical outcomes; Conclusion; References; 10 Multiplate Analyzer; Historical background; Principles of the Multiplate® analyzer; Advantages; Disadvantages; Clinical studies in cardiovascular medicine; Studies in cardiovascular surgery"]
[{"$nulls":4},"Consensus definitions and cutoff values concerning platelet reactivitySummary; Acknowledgment; References; 11 Shear Stress-Based Platelet Function Tests; PFA-100; IMPACT-R; References; 12 Thrombelastography and Other Novel Techniques; Novel techniques; T2 magnetic resonance (T2MR); Shear-induced platelet aggregation assays; References; Section III Antiplatelet pharmacology; 13 Aspirin; Mode of antiplatelet action; Time dependency of inhibition of platelet function by aspirin; Dose-dependent inhibition of platelet function by aspirin; Negative interactions with other drugs"]
[{"$nulls":4},"Positive interactions with other drugs"]
[null,null,null,"Sommario/riassunto","Edited by one of the world's leading interventional cardiologists and educators, this new book is created with an eye on giving the reader a solid, practical and clinically-focused understanding of this important class of drugs, from basic science to a clear-headed discussion of complex topics such as combination therapies, drug-drug interactions, and platelet resistance.   This important new book:   Begins with a concise but thorough discussion of platelet biology and pathophysiology so that readers understand how these therapies work and why they can also produce such a varied"]