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[null,"1.","Record Nr.",null,"UNIBAS000036034"]
[null,null,"Autore",null,"Terentius Afer, Publius <195-159 a.C.>"]
[null,null,"Titolo",null,"Le commedie / Terenzio ; introduzione e traduzione di Alessandro Ronconi"]
[null,null,"Pubbl/distr/stampa",null,"Firenze : Le Monnier, 1960"]
[null,null,"Descrizione fisica",null,"XXVII, 318 p. ; 19 cm"]
[null,null,"Collana",null,"Biblioteca nazionale , Serie dei classici greci e latini tradotti"]
[null,null,"Disciplina",null,"872.01"]
[null,null,"Soggetti",null,"Commedia latina"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910143986903321"]
[null,null,"Titolo",null,"Immunotoxicology strategies for pharmaceutical safety assessment [[electronic resource] /] / edited by Danuta J. Herzyk and Jeanine L. Bussiere"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, N.J., : Wiley, c2008"]
[null,null,"ISBN",null,"1-281-78802-3"]
[{"$nulls":4},"9786611788025"]
[{"$nulls":4},"0-470-38638-X"]
[{"$nulls":4},"0-470-38637-1"]
[null,null,"Descrizione fisica",null,"1 online resource (432 p.)"]
[null,null,"Disciplina",null,"615.19"]
[{"$nulls":4},"616.97/071"]
[null,null,"Soggetti",null,"Immunotoxicology"]
[{"$nulls":4},"Immune system - Effect of drugs on"]
[{"$nulls":4},"Toxicity testing"]
[{"$nulls":4},"Drugs - Toxicology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Current regulatory expectations for immunotoxicologyy evaluation of pharmaceuticals / Kenneth L. Hastings -- Clinical pathology as crucial insight into immunotoxicity testing / Ellen Evans -- Histomorphology of the immune system : a basic step in assessing immunotoxicity / Patrick Haley --"]
[{"$nulls":4},"Need for specialized immunotoxicity tests / Kazuichi Nakamura -- Specific drug-induced immunotoxicity : immune-mediated hemolytic anemia / Raj Krishnaraj -- T cell-dependent antibody response tests / Joseph R. Piccotti -- Natural killer cell assay and other innate immunity tests / Lisa Plitnick -- Cellular immune response in delayed-type hypersensitivity test / Karen Price -- Evaluation of drug effects on immune cell phenotypes / Laurie Iciek --"]
[{"$nulls":4},"Functional cellular responses and cytokine profiles / Elizabeth R. Gore -- Application of flow cytometry in drug development / Padma Narayanan ... [et al.] -- Animal models of host resistance / Gary R. Burleson and Florence G. Burleson -- Approaches to evaluation of autoimmunity / Danuta J. Herzyk --"]
[{"$nulls":4},"Differentiating between desired immunomodulation and potential "]
[{"$nulls":4},"immunotoxicity / Jeanine L. Bussiere and Barbara Mounho -- Relevant immune tests across different species and surrogate models / Jeanine L. Bussiere -- Antidrug antibody responses in nonclinical studies and their implications / Barbara Mounho -- Pharmacological immunogenicity and adverse responses to vaccines / Mary Kate Hart, Mark Bolanowski, and Robert V. House --"]
[{"$nulls":4},"Immunotoxicological concerns for vaccines and adjuvants / Catherine Kaplanski ... [et al.] -- Systemic hypersensitivity / Raymond Pieters -- Nonclinical models to assess respiratory hypersensitivity potential / Curtis C. Maier -- Developmental immunotoxicity in rodents / Rodney R. Dietert and Leigh Ann Burns-Naas -- Developmental immunotoxicity in nonhuman primates / Pauline L. Martin and Eberhard Buse --"]
[{"$nulls":4},"Alternative animal models for immunomodulation and immunotoxicity / Peter J. Bugelski -- Animal models for preclinical comparative immunogenicity testing / Daniel Wierda -- T cell epitopes and minimization of immunogenicity / Harald Kropshoffer and Thomas Singer -- Bridging immunotoxicology to clinical drug development / Ian Gourley and Jacques Descotes."]
[null,null,null,"Sommario/riassunto","An important reference which provides an overview of the current and recently introduced methodologies for testing the immunotoxic risks in drug candidatesHelps readers understand the significance of the methods and approaches to immunotoxicology testingAids drug scientists in industry and regulatory areas to consolidate approaches to immunotox testingOffers a definitive assessment of nonclinical models to study the toxic impacts (bio)pharmaceuticals can have on the immune systemIncludes chapter authors from across the ph"]