LEADER 01179nam--2200361---4500 001 990000590180203316 005 20091124161110.0 010 $a88-14-06996-4 035 $a0059018 035 $aUSA010059018 035 $a(ALEPH)000059018USA01 035 $a0059018 100 $a20010828d1998----km-y0ENGy0103----ba 101 $aita 102 $aIT 200 1 $aImprese e industria finanziaria nel processo di globalizzazione$fEnrico Cotta Ramusino 210 $aMilano$cGiuffrè$dc1998 215 $aVI, 195 p.$d24 cm 225 2 $aEconomia e gestione delle imprese 410 $12001$aEconomia e gestione delle imprese 676 $a358.15 700 1$aCOTTA RAMUSINO,$bEnrico$0240671 801 0$aIT$bsalbc$gISBD 912 $a990000590180203316 951 $aXXX.B. Coll. 46/ 4 (COLL. HGP 4)$b16725 G$cXXX.B. Coll. 46/ 4 (COLL. HGP)$d00252416 959 $aBK 969 $aGIU 979 $aPATRY$b90$c20010828$lUSA01$h1144 979 $c20020403$lUSA01$h1708 979 $aPATRY$b90$c20040406$lUSA01$h1641 979 $aRSIAV4$b90$c20091124$lUSA01$h1611 996 $aImprese e industria finanziaria nel processo di globalizzazione$9416854 997 $aUNISA LEADER 03287nam 2200781 450 001 9910132261703321 005 20220504000034.0 010 $a3-527-67364-4 010 $a3-527-67366-0 035 $a(CKB)3710000000370188 035 $a(EBL)1977788 035 $a(SSID)ssj0001534291 035 $a(PQKBManifestationID)12590105 035 $a(PQKBTitleCode)TC0001534291 035 $a(PQKBWorkID)11494953 035 $a(PQKB)11705458 035 $a(MiAaPQ)EBC1977788 035 $a(Au-PeEL)EBL1977788 035 $a(CaPaEBR)ebr11048186 035 $a(CaONFJC)MIL769783 035 $a(OCoLC)904518353 035 $a(PPN)19641122X 035 $a(EXLCZ)993710000000370188 100 $a20150505h20152015 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAntitargets and drug safety /$fedited by La?slo? Urba?n, Vinod F. Patel, and Roy J. Vaz 210 1$aWeinheim, Germany :$cWiley-VCH,$d[2015] 210 4$d©2015 215 $a1 online resource (1266 p.) 225 1 $aMethods and principles in medicinal chemistry ;$vvolume 66 300 $aDescription based upon print version of record. 311 $a3-527-67367-9 311 $a3-527-33511-0 320 $aIncludes bibliographical references and index. 327 $asection 1. General concept for target-based safety assessment -- section 2. Hepatic side effects -- section 3. Cardiovascular side effects -- section 4. Kinase antitargets -- section 5. Examples of clinical translation. 330 $aWith its focus on emerging concerns of kinase and GPCR-mediated antitarget effects, this vital reference for drug developers addresses one of the hot topics in drug safety now and in future. Divided into three major parts, the first section deals with novel technologies and includes the utility of adverse event reports to drug discovery, the translational aspects of preclinical safety findings, broader computational prediction of drug side-effects, and a description of the serotonergic system. The main part of the book looks at some of the most common antitarget-mediated side effects, focusing 410 0$aMethods and principles in medicinal chemistry ;$vv. 66. 606 $aDrugs$xSide effects 606 $aDrugs$xSide effects$xPrevention 606 $aDrug interactions 606 $aDrug development 606 $aDrugs$xStructure-activity relationships 606 $aDrug-Related Side Effects and Adverse Reactions 606 $aProtein Kinase Inhibitors$xadverse effects 606 $aPharmacovigilance 615 0$aDrugs$xSide effects. 615 0$aDrugs$xSide effects$xPrevention. 615 0$aDrug interactions. 615 0$aDrug development. 615 0$aDrugs$xStructure-activity relationships. 615 12$aDrug-Related Side Effects and Adverse Reactions. 615 22$aProtein Kinase Inhibitors$xadverse effects, 615 22$aPharmacovigilance. 676 $a615.19 702 $aUrba?n$b La?slo? 702 $aPatel$b Vinod F. 702 $aVaz$b Roy J. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910132261703321 996 $aAntitargets and drug safety$92286568 997 $aUNINA LEADER 01321cam0 22002893 450 001 SOB020795 005 20240716074757.0 010 $a881410073X 100 $a20040211d2003 |||||ita|0103 ba 101 $aita 102 $aIT 200 1 $a<>titoli edilizi nel Testo Unico e nella legge obiettivo$eprofili amministrativi e penali. Testo coordinato ed aggiornato alla legge 1 agosto 2002, n.166 al decreto legislativo 20 agosto 2002, n.190 ed al decreto legislativo 27 dicembre 2002, n.301$fRosanna De Nictolis$gVito Poli 210 $aMilano$cGiuffrè$d2003 215 $aXX, 428 p.$d24 cm 225 2 $aTeoria e pratica del diritto$hSezione 4$xDiritto amministrativo$vSez.IV - 65 410 1$1001LAEC00027165$12001 $a*Teoria e pratica del diritto. Sezione 4, Diritto amministrativo$vSez.IV - 65 700 1$aDe_Nictolis$b, Rosanna$3AF00013030$4070$0147554 702 1$aPOLI, Vito$3AF00023116$4070 801 0$aIT$bUNISOB$c20240716$gRICA 850 $aUNISOB 852 $aUNISOB$j340|Coll|47|K$m114373 912 $aSOB020795 940 $aM 102 Monografia moderna SBN 941 $aM 957 $a340|Coll|47|K$b000018$gSI$d114373$rACQUISTO$1Alfano$2UNISOB$3UNISOB$420240716074645.0$520240716074739.0$6Alfano 996 $aTitoli edilizi nel Testo Unico e nella legge obiettivo$91676238 997 $aUNISOB