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200 1 $aHandbook of metaheuristics$fedited by Fred Glover, Gary A. Kochenberger
210   $aBoston [etc.]$cKluwer academic$dc2003
215   $aXII, 556 p.$d24 cm.
225 | $aInternational series in operations research & management science
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200 00$aCancer and stem cells /$fThomas Dittmar and Kurt S. Za?nker, editors
205   $a1st ed.
210   $aNew York $cNova Biomedical Books$dc2008
215   $a1 online resource (231 p.)
300   $aDescription based upon print version of record.
311 08$a1-60456-478-4 
320   $aIncludes bibliographical references and index.
327   $aCancer stem cells: a definition / Jichao Qin, Dean G. Tang -- Mathematical modeling of stem cells related to cancer / Monika Joanna Piotrowska ... [et al.] -- Where do cancer stem cells come from? / Calin Stoicov and JeanMarie Houghton -- Mismatch repair deficiencies and origin of cancer stem cells / Minal Garg -- Cancer stem cells in hematological malignancies / Aniruddha J. Deshpande and Christian Buske -- Stem cells in solid tumors / Andres Matoso and Alexander Yu. Nikitin -- Cancer stem cells and metastasis / Benjamin Tiede and Yibin Kang -- Exercise, stem cells, and cancer / Emre Tunca, Karsten Kru?ger, Frank C. Mooren -- Human adult stem cells as targets for cancer stem cells: evolution: OCT-4 gene and cell to cell communication / James E. Trosko -- Targeting cancer stem cells / Thomas Dittmar and Kurt S. Za?nker.
330   $aToday, cancer is the second most prevelant cause of death, after heart disease, in the industrialized world. Till now, and despite promising results in cancer research, the primary cause of death in cancer is still 1: the formation of metastases at distant organs sites, 2: the presence of cancer cells that are resistant to current cancer therapies (chemotherapy/radiation) and which cause cancer relapse. Within the past three years it became evident that also solid tumor tissues contain a kind of stem cells, so-called cancer cells. These cancer stem cells have been described as chemo-/radiation therapy resistant tumor initating cells. The purpose of this book is to summarize the latest findings about the role of stem cells in cancer.
606   $aCancer cells
606   $aStem cells
615  0$aCancer cells.
615  0$aStem cells.
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701   $aZa?nker$b Kurt S$01867199
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