LEADER 03824nam 22007335 450 001 9910782093903321 005 20230810203655.0 010 $a3-540-78899-9 024 7 $a10.1007/978-3-540-78899-7 035 $a(CKB)1000000000492376 035 $a(EBL)364077 035 $a(OCoLC)288467972 035 $a(SSID)ssj0000152786 035 $a(PQKBManifestationID)11163183 035 $a(PQKBTitleCode)TC0000152786 035 $a(PQKBWorkID)10339956 035 $a(PQKB)10392832 035 $a(DE-He213)978-3-540-78899-7 035 $a(MiAaPQ)EBC364077 035 $a(Au-PeEL)EBL364077 035 $a(CaPaEBR)ebr10253708 035 $a(PPN)12906226X 035 $a(EXLCZ)991000000000492376 100 $a20100301d2008 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFacilitative Glucose Transporters in Articular Chondrocytes$b[electronic resource] $eExpression, Distribution and Functional Regulation of GLUT Isoforms by Hypoxia, Hypoxia Mimetics, Growth Factors and Pro-Inflammatory Cytokines /$fby Ali Mobasheri, Carolyn A. Bondy, Kelle Moley, Alexandrina Ferreira Mendes, Susana Carvalho Rosa, Stephen Richardson, Judith A Hoyland, Richard Barrett-Jolley, Mehdi Shakibaei 205 $a1st ed. 2008. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2008. 215 $a1 online resource (vi, 88 pages) $cillustrations 225 1 $aAdvances in Anatomy, Embryology and Cell Biology,$x2192-7065 ;$v200 300 $aDescription based upon print version of record. 311 0 $a3-540-78898-0 320 $aIncludes bibliographical references and index. 327 $aArticular Cartilage: Structure, Function, and Pathophysiology -- Does Arthritis Have a Nutritional Etiology? -- Metabolic Dysfunction in Arthritis -- Glucose: An Essential Metabolite and Structural Precursor for Articular Cartilage -- Mammalian Sugar Transporter Families: GLUT and SGLT -- Molecular Diversity of Facilitative Glucose Transporters in Articular Chondrocytes -- Regulation of Glucose Transport by Nonsteroidal Anti-inflammatory Drugs -- Glucose Transporters in the Intervertebral Disc -- Glucose Transporter Expression and Regulation in Embryonic and Mesenchymal Stem Cells -- Concluding Remarks. 330 $aArticular cartilage is a unique and highly specialized avascular connective tissue in which the availability of oxygen and glucose is significantly lower than synovial fluid and plasma. Glucose is an essential source of energy during embryonic growth and fetal development and is vital for mesenchymal cell differentiation, chondrogenesis and skeletal morphogenesis. Glucose is an important metabolic fuel for differentiated chondrocytes during post-natal development and in adult articular cartilage and is a common structural precursor for the synthesis of extracellular matrix glycosaminoglycans. 410 0$aAdvances in Anatomy, Embryology and Cell Biology,$x2192-7065 ;$v200 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aOrthopedics 606 $aEndocrinology 606 $aBiomedical Research 606 $aOrthopaedics 606 $aEndocrinology 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aOrthopedics. 615 0$aEndocrinology. 615 14$aBiomedical Research. 615 24$aOrthopaedics. 615 24$aEndocrinology. 676 $a612.75 676 $a613.283 701 $aMobasheri$b A$g(Ali)$01469261 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910782093903321 996 $aFacilitative Glucose Transporters in Articular Chondrocytes$93680687 997 $aUNINA LEADER 02173nam a2200421 i 4500 001 991004382137907536 005 20250516124056.0 008 900209m19901996it er e 001 0 ita d 020 $a8802043205 (v. 1) 020 $a8802044007 (v. 2) 020 $a8802043213 (v. 3) 020 $a8802050368 (v. 5) 020 $a880205178X (v. 6) 040 $aBibl. 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