LEADER 03628nam 22005175 450 001 9910350312903321 005 20181112071520.0 010 $a981-13-2402-6 024 7 $a10.1007/978-981-13-2402-4 035 $a(CKB)4100000006671787 035 $a(MiAaPQ)EBC5517004 035 $a(DE-He213)978-981-13-2402-4 035 $a(EXLCZ)994100000006671787 100 $a20180914d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPatient-Specific Controller for an Implantable Artificial Pancreas$b[electronic resource] /$fby Yvonne Ho 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (97 pages) 225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 311 $a981-13-2401-8 327 $aIntroduction -- Glucose Metabolism and Diabetes -- Literature Review -- Design of an Implantable Artificial Pancreas -- Model Predictive Controller using Interior Point and Ant Algorithm -- In Vivo Experiment of the Implantable Artificial Pancreas -- Parameter Estimation for Nonlinear Mathematical Model -- Conclusion and Future Work. 330 $aThe thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country?s prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into the development of an implantable artificial pancreas that can regulate blood glucose levels by delivering appropriate dosages of insulin when necessary. By sensing blood glucose and injecting insulin directly into the vein, the implantable device aims to remove delays that occur with subcutaneous blood glucose sensing and insulin delivery. Preliminary in-vitro and in-vivo experimental results suggest that the implantable device for blood glucose control could be a clinically viable alternative to pancreas transplant. 410 0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 606 $aBiomedical engineering 606 $aDiabetes 606 $aBiomedical Engineering and Bioengineering$3http://scigraph.springernature.com/things/product-market-codes/T2700X 606 $aBiomedical Engineering/Biotechnology$3http://scigraph.springernature.com/things/product-market-codes/B24000 606 $aDiabetes$3http://scigraph.springernature.com/things/product-market-codes/H33045 606 $aControl and Systems Theory$3http://scigraph.springernature.com/things/product-market-codes/T19010 615 0$aBiomedical engineering. 615 0$aDiabetes. 615 14$aBiomedical Engineering and Bioengineering. 615 24$aBiomedical Engineering/Biotechnology. 615 24$aDiabetes. 615 24$aControl and Systems Theory. 676 $a616.462025 700 $aHo$b Yvonne $4aut$4http://id.loc.gov/vocabulary/relators/aut$0871313 906 $aBOOK 912 $a9910350312903321 996 $aPatient-Specific Controller for an Implantable Artificial Pancreas$91945079 997 $aUNINA LEADER 01097nam a2200241 i 4500 001 991004079619707536 008 111208s2008 it b 001 0 ita d 035 $ab13797426-39ule_inst 040 $aDip.to Matematica$beng 084 $aAMS 14H52 084 $aAMS 20K01 100 1 $aPerrone, Antonella$0446433 245 10$aStruttura del gruppo delle curve ellittiche e il metodo di fattorizzazione di Lenstra. Tesi di laurea /$claureanda Antonella Perrone; relat. Mauro Biliotti 260 $aLecce :$bUniversità del Salento. Facoltà di Scienze MM. FF. NN. Corso di laurea in Matematica e Informatica,$ca.a. 2007-08 300 $a53 p. ;$c30 cm 650 4$aElliptic curves 700 1 $aBiliotti, Mauro 907 $a.b13797426$b02-04-14$c11-12-08 912 $a991004079619707536 945 $aLE013 TES 2007/08 PER1 $g1$lle013$og$pE15.00$q-$rn$so $t1$u0$v0$w0$x0$y.i14902825$z11-12-08 996 $aStruttura del gruppo delle curve ellittiche e il metodo di fattorizzazione di Lenstra. Tesi di laurea$91224185 997 $aUNISALENTO 998 $ale013$b11-12-08$cm$da $e-$fita$git $h0$i0