LEADER 00874nam a2200265 i 4500 001 991004006489707536 005 20020506112139.0 008 941010s1988 it ||| | ita 020 $a8878020540 035 $ab10586490-39ule_inst 035 $aEXGIL130645$9ExL 040 $aDip.to Filol. Ling. e Lett.$bita 100 1 $aMazzoni, Grazia$0470525 245 13$aIl postmoderno e la critica /$cGrazia Mazzoni 260 $aMilano :$bGuerini,$c1988 300 $a112 p. ;$c21 cm. 490 0 $aRicerche 650 4$aLetteratura 650 4$aPostmoderno 907 $a.b10586490$b23-02-17$c27-06-02 912 $a991004006489707536 945 $aLE008 LLI V E 4$g1$i2008000282790$lle008$o-$pE0.00$q-$rn$sm $t0$u1$v1$w1$x0$y.i10670403$z27-06-02 996 $aPostmoderno e la critica$9237390 997 $aUNISALENTO 998 $ale008$b01-01-94$cm$da $e-$fita$git $h3$i1 LEADER 01205nam 2200397 450 001 9910148705903321 005 20110504082249.0 010 $a1-61728-242-1 035 $a(CKB)3710000000922380 035 $a(MiAaPQ)EBC4743788 035 $a(EXLCZ)993710000000922380 100 $a20100325h20102010 uy| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aDesalination $emethods, costs and technology /$fIrena A. Urboniene?, editor 210 1$aHauppauge, New York :$cNova Science Publishers,$d[2010] 210 4$dİ2010 215 $a1 online resource (367 pages) $cillustrations (some color) 225 1 $aAgriculture issues and policies 311 $a1-61668-909-9 320 $aIncludes bibliographical references and index. 410 0$aAgriculture issues and policies. 606 $aSaline water conversion plants 615 0$aSaline water conversion plants. 676 $a628.1/67 702 $aUrboniene?$b Irena A. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910148705903321 996 $aDesalination$9797661 997 $aUNINA LEADER 02955nam 2200409z- 450 001 9910220038803321 005 20210211 035 $a(CKB)3800000000216389 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/50013 035 $a(oapen)doab50013 035 $a(EXLCZ)993800000000216389 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aThe Impact of Systems Medicine on Human Health and Disease 210 $cFrontiers Media SA$d2017 215 $a1 online resource (96 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-140-2 330 $aComplex diseases including diabetes, neurological disorders and cancer are results from a combination of genetic, environmental and lifestyle factors, and development of new prognostic tools for the treatment of such diseases requires a deep understanding of the mechanisms underlying cell functions. With the advances in high throughput technologies, biological components of cells can be measured with a very high resolution and these data can be used for investigating whole systems properties using a network-based approach. Systems medicine provides an integrative platform for studying the interactions between the biological components of the cell using a holistic approach and generating mechanistic explanations for the emergent systems properties. This inter-disciplinary field of study allows for understanding biological processes of cells in health and disease states, gaining new insights into what drives the appearance of the disease and finally identifying proteins and metabolites implicated in human disease. Systems medicine utilizes mathematical approaches to generate models which can be employed for designing new sets of experiments and for mapping the response of the system to perturbations quantitatively. These models, as well as the developed tools, can accelerate the emergence of personalized medicine which can transform the practice of medicine and offer better targets for drug development with minimum side effects. In this Research Topic, we aim to review the recently developed tools for modeling the cell behavior in normal and pathological states, recent advances and findings which increase our understanding of the molecular mechanisms involved in the progression of the diseases. 606 $aNeurosciences$2bicssc 610 $abiological networks 610 $aMetabolic Diseases 610 $aMetabolic Networks and Pathways 610 $aNetworks medicine 610 $aSystems Biology 610 $aSystems Medicine 615 7$aNeurosciences 700 $aAdil Mardinoglu$4auth$01285368 702 $aJens Nielsen$4auth 906 $aBOOK 912 $a9910220038803321 996 $aThe Impact of Systems Medicine on Human Health and Disease$93019547 997 $aUNINA