LEADER 00837nam a2200229 i 4500 001 991004000759707536 005 20020506112059.0 008 010315s1968 it ||| | ita 035 $ab10585667-39ule_inst 035 $aEXGIL130545$9ExL 040 $aBiblioteca Interfacoltà$bita 082 0 $a851.914 100 1 $aD'Andrea, Ercole Ugo$0445965 245 13$aLa porta delle pecore /$cErcole Ugo D'Andrea ; prefazione di Carlo Betocchi 260 $a[S.l.] :$bLibreria editrice fiorentina,$c1968 300 $a23 p. ;$c21 cm. 907 $a.b10585667$b02-04-14$c27-06-02 912 $a991004000759707536 945 $aLE002 Busta 58 2$g1$i2002000637048$lle002$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i10669565$z27-06-02 996 $aPorta delle pecore$9237330 997 $aUNISALENTO 998 $ale002$b01-01-01$cm$da $e-$fita$git $h3$i1 LEADER 04320nam 22006015 450 001 9910253957303321 005 20200701171354.0 010 $a3-319-68948-7 024 7 $a10.1007/978-3-319-68948-7 035 $a(CKB)4100000001382014 035 $a(DE-He213)978-3-319-68948-7 035 $a(MiAaPQ)EBC5210136 035 $a(PPN)222228121 035 $a(EXLCZ)994100000001382014 100 $a20171223d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMarburg- and Ebolaviruses $eFrom Ecosystems to Molecules /$fedited by Elke Mühlberger, Lisa L. Hensley, Jonathan S. Towner 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (X, 460 p.) 225 1 $aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v411 311 $a3-319-68946-0 320 $aIncludes bibliographical references at the end of each chapters. 327 $aFilovirus Research: How it began -- Ecology of Filoviruses -- West Africa 2013 Ebola: From Virus Outbreak to Humanitarian Crisis -- Clinical Management of Ebola Virus Disease Patients in Low Resource Settings -- Clinical Management of Patients with Ebola Virus Disease in High Resource Settings -- Ebola Virus Disease in Humans: Pathophysiology and Immunity -- Nonhuman Primate Models of Ebola Virus Disease -- Small Animal Models for Studying Filovirus Pathogenesis -- Accelerating Vaccine Development during the West African Ebola Virus Disease Outbreak -- Therapeutics against Filovirus Infection -- Filovirus Strategies to Escape Antiviral Responses -- Mechanisms of Filovirus Entry -- Inside the Cell: Assembly of Filoviruses -- Filovirus Structural Biology: The Molecules in the Machine -- Reverse Genetics of Filoviruses -- Guide to the Correct Use of Filoviral Nomenclature. 330 $aThis volume provides an overview of recent advances in our understanding of the biology of marburg- and ebolaviruses. It focuses on four essential areas: 1) ecology, outbreaks and clinical management, 2) disease, pathogenesis and protection, 3) virus replication inside the cell, and 4) molecular tools for virus study and taxonomy. For 50 years, these viruses have spilled over sporadically and without warning from their wildlife reservoirs, often causing major outbreaks and high fatalities. The consequences can be devastating, with a clear potential for global reach, as demonstrated by the 2013 West African outbreak of Ebola virus, which led to over 28,000 reported cases across three continents and more than 11,000 deaths. Given the international threat posed by these viruses, the pace and scope of basic research have also greatly intensified, ranging from studies of virus emergence, epidemiology, antiviral countermeasures and human disease to detailed mechanistic studies of virus entry, replication, virion assembly and protein structure. Written by internationally respected experts, this book will appeal to a wide audience and be a valuable resource for basic researchers, clinicians and advanced students alike. 410 0$aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v411 606 $aVirology 606 $aInfectious diseases 606 $aEpidemiology 606 $aVirology$3https://scigraph.springernature.com/ontologies/product-market-codes/B22003 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aEpidemiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H63000 615 0$aVirology. 615 0$aInfectious diseases. 615 0$aEpidemiology. 615 14$aVirology. 615 24$aInfectious Diseases. 615 24$aEpidemiology. 676 $a579.25 702 $aMühlberger$b Elke$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHensley$b Lisa L$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aTowner$b Jonathan S$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253957303321 996 $aMarburg- and Ebolaviruses$92233550 997 $aUNINA