LEADER 02501nam 2200349 450 001 9910524661303321 005 20221224154823.0 035 $a(CKB)5360000000000992 035 $a(NjHacI)995360000000000992 035 $a(EXLCZ)995360000000000992 100 $a20221224d2017 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSteamboats and Sailors of the Great Lakes /$fMark L. Thompson 210 1$aDetroit :$cWayne State University Press,$d2017. 215 $a1 online resource (231 pages) $cillustrations 225 0 $aGreat Lakes Books Series 311 $a0-8143-3835-6 330 $aThe Great Lakes shipping industry can trace its lineage to 1679 with the launching on Lake Erie of the Griffon, a sixty-foot galley weighing nearly fifty tons. Built by LaSalle, a French explorer who had been commissioned to search for a passage through North America to China, it was the first sailing ship to operate on the upper lakes, signaling the dawn of the Great Lakes shipping industry as we know it today. Steamboats and Sailors of the Great Lakes is the most thorough and factual study of the Great Lakes shipping industry written this century. Author Mark L. Thompson tells the fascinating story of the world's most efficient bulk transportation system, describing the Great Lakes freighters, the cargoes of the great ships, and the men and women who have served as crew. He documents the dramatic changes that have taken places in the industry and looks at the critical role that Great Lakes shipping plays in the economic well-being of the U.S. and Canada, despite the fact tat the size of the fleet and the amount of cargo carried have declined dramatically in recent years. Spanning more than three centuries, from LaSalle's voyage in 1679, through 1975 with the mysterious sinking of the Edmund Fitzgerald, to life aboard today's thousand-foot behemoths, this important volume documents the evolution of the industry through its "Golden Age" at the end of the nineteenth century to the present, with a downsized U.S. fleet that numbers fewer than seventy vessels. 606 $aSteamboats$xHistory 615 0$aSteamboats$xHistory. 676 $a387.24 700 $aThompson$b Mark L.$0277407 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910524661303321 996 $aSteamboats and Sailors of the Great Lakes$92996465 997 $aUNINA LEADER 01052nam a22002651i 4500 001 991003610759707536 005 20030911092433.0 008 031111s1972 it |||||||||||||||||ita 035 $ab12450285-39ule_inst 035 $aARCHE-048357$9ExL 040 $aDip.to Lingue$bita$cA.t.i. Arché s.c.r.l. Pandora Sicilia s.r.l. 082 04$a833.6 100 1 $aArnim, Ludwig Achim :$cvon$0161539 245 10$aIsabella d'Egitto primo amore di Carlo V /$cAchim von Arnim ; nota introduttiva di Claudio Magris ; traduzione di Rosa Spaini 260 $aTorino :$bEinaudi,$c[1972] 300 $aXV, 136 p. ;$c20 cm 440 0$aCentopagine ;$v15 700 1 $aMagris, Claudio 700 1 $aSpaini, Rosa 907 $a.b12450285$b02-04-14$c13-11-03 912 $a991003610759707536 945 $aLE012 F.G. 58$g1$i2012000054912$lle012$o-$pE0.00$q-$rl$s- $t0$u3$v0$w3$x0$y.i12877542$z13-11-03 996 $aIsabella von Ägypten, Kaiser Karls des Fünften erste Jugendliebe$918638 997 $aUNISALENTO 998 $ale012$b13-11-03$cm$da $e-$fita$git $h0$i1 LEADER 03551nam 2200529Ia 450 001 9910779646103321 005 20230721010730.0 010 $a1-60876-720-5 035 $a(CKB)2550000001041403 035 $a(EBL)3018589 035 $a(SSID)ssj0000836221 035 $a(PQKBManifestationID)11461968 035 $a(PQKBTitleCode)TC0000836221 035 $a(PQKBWorkID)11007781 035 $a(PQKB)10628907 035 $a(MiAaPQ)EBC3018589 035 $a(Au-PeEL)EBL3018589 035 $a(CaPaEBR)ebr10660450 035 $a(OCoLC)923659016 035 $a(EXLCZ)992550000001041403 100 $a20090213d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTelomeres$b[electronic resource] $efunction, shortening and lengthening /$fLeonardo Mancini, editor 210 $aNew York $cNova Biomedical Books$dc2009 215 $a1 online resource (498 p.) 300 $aDescription based upon print version of record. 311 $a1-60692-350-1 320 $aIncludes bibliographical references and index. 327 $aTelomere dynamics and biology in human progeroid syndromes / Terence Davis, Hannah S.E. Tivey, and David Kipling -- The role of telomere-telomerase system in age-related fitness decline : a tameable process / Giacinto Libertini -- Cytogenetic evaluation of telomere dysfunction : chromosomal aberrations involving telomeres and interstitial telomeric sequences / Alejandro D. Bolza?n -- Telomeres-telomerase biology and their role in renal and other chronic diseases / Kordinas Vasileios ... [et al.] -- Telomerase and telomere dynamics in cancer : clinical application for cancer diagnosis / Eiso Hiyama, Keiko Hiyama -- Telomeres and chromosome segregation / Antonella Sgura and Daniela Cimini -- Telomere-based genome-protective responses : a mammalian improvement on the bacterial SOS response? / Barbara A. Gilchrest, Mark S. Eller -- Telomere lengthening from oocyte to embryonic stem cell / Eva Pericuesta ... [et al.] -- Transcriptional activity at the telomeres of chironomus (diptera) : its possible role in the lengthening of the telomeres / J.L. Diez ... [et al.] -- 327 $aTelomerase activity : application to diagnosis of human carcinoma / Liliana N. Guerra -- Telomere shortening in diabetes mellitus / Nicholas Tentolouris, Athanasia Papazafiropoulou -- Do alterations in the three-dimensional organization of telomeres indicate malignant transformation? / Sandrine Lacoste, Hans Knecht, and Sabine Mai -- Telomeres : function, shortening and lengthening / Barry Flanary -- Telomerase regulation in stem cells : how to flip the switch? / Rich Allsopp -- Telomere maintenance mechanisms in bone and soft tissue tumors / Toshihiro Matsuo ... [et al.] -- Genetic polymorphisms of human telomerase reverse transcriptase (hTERT) : mini review / Yumiko Matsubara, Mitsuru Murata, and Yasuo Ikeda -- Genetic inhibition of telomere lengthening in cancer prevention and treatment / F. Mathias Bollmann -- Telomeres : function, shortening, and lengthening / Barry Flanary -- Clinical implications of telomerase activity in human brain tumors / Hyoung-Joon Chun ... [et al.]. 606 $aTelomere 606 $aTelomerase 615 0$aTelomere. 615 0$aTelomerase. 676 $a572.8/7 701 $aMancini$b Leonardo$01476655 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910779646103321 996 $aTelomeres$93691392 997 $aUNINA