LEADER 02066cam a22003858a 4500 001 991003522989707536 008 080401s2008 nju b 001 0 eng d 020 $a9789812707048 (hardcover) 020 $a9812707042 (hardcover) 035 $ab13709513-39ule_inst 040 $aDip.to Fisica$beng 082 00$a572.80285$222 084 $aLC QH324.2 084 $a510.62 100 1 $aZhou, Xiaobo$0628188 245 10$aComputational systems bioinformatics :$bmethods and biomedical applications /$cby Xiaobo Zhou and Stephen T.C. Wong 260 $a[Hackensack, N.J.] :$bWorld Scientific Pub.,$c2008 300 $ax, 387 p. :$bill. (some col.), diagrs., graphs, tables ;$c23 cm 504 $aIncludes bibliographical references and index 505 0 $aMathematical, statistical, and data mining principles -- Missing value estimation using KNN and Bayesian methods -- Normalization, scaling, and discretization -- Cross-platform comparison -- Discovering differential biomarkers -- Gene selection and classification -- Gene clustering -- Gene prediction 505 0 $aReverse engineering : gene regulatory network construction and its behavior -- Motif detection and transcription factor binding site (TFBS) identification -- Gene interaction based on combined microarray and sequence technology -- Protein structure informatics -- Biomarker discovery from proteomics -- Bio-imaging informatics 650 0$aComputational biology 650 0$aDNA microarrays 650 0$aBioinformatics 650 12$aComputational Biology$xMethods 650 22$aMicroarray Analysis$xMethods. 650 22$aOligonucleotide Array Sequence Analysis$xMethods 650 22$aStatistics$xMethods 700 1 $aWong, Stephen T.C. 907 $a.b13709513$b28-01-14$c01-04-08 912 $a991003522989707536 945 $aLE006 510.62+510.65 ZHO$g1$i2006000161756$lle006$op$pE44.53$q-$rl$s- $t0$u3$v0$w3$x0$y.i14706507$z01-04-08 996 $aComputational systems bioinformatics$91229262 997 $aUNISALENTO 998 $ale006$b01-04-08$cm$da $e-$feng$gnju$h0$i0