LEADER 00897nam a2200217 i 4500 001 991003442359707536 008 180112s1957 it 000 0 ita d 035 $ab14334392-39ule_inst 040 $aBibl. Interfacoltà T. Pellegrino$bita 100 1 $aGalilei, Galileo$04160 245 10$aDal Dialogo dei massimi sistemi :$bgiornata seconda /$cGalileo Galilei ; a cura di Angiolo Maros Dell'Oro 260 $aRoma :$bA. Signorelli,$cstampa 1957 300 $a106 p. ;$c21 cm. 490 1 $aClassici della filosofia e della pedagogia 700 1 $aDell'Oro, Angiolo Maros 907 $a.b14334392$b12-01-18$c12-01-18 912 $a991003442359707536 945 $aLE002 Fondo Roggerone 120$g1$i2002001070028$lle002$og$pE0.00$q-$rn$so $t0$u0$v0$w0$x0$y.i15828529$z12-01-18 996 $aDal Dialogo dei massimi sistemi$91495534 997 $aUNISALENTO 998 $ale002$b12-01-18$cm$da $e $fita$git $h0$i0 LEADER 02971nam 22005774a 450 001 9910830085003321 005 20230721033134.0 010 $a1-281-93868-8 010 $a9786611938680 010 $a0-470-40910-X 010 $a0-470-40905-3 035 $a(CKB)1000000000551811 035 $a(EBL)380501 035 $a(OCoLC)437241459 035 $a(SSID)ssj0000212701 035 $a(PQKBManifestationID)11173616 035 $a(PQKBTitleCode)TC0000212701 035 $a(PQKBWorkID)10138878 035 $a(PQKB)10551139 035 $a(MiAaPQ)EBC380501 035 $a(EXLCZ)991000000000551811 100 $a20080703d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNuclear receptors in drug metabolism$b[electronic resource] /$fedited by Wen Xie 210 $aHoboken, NJ $cJohn Wiley & Sons$dc2009 215 $a1 online resource (362 p.) 300 $aDescription based upon print version of record. 311 $a0-470-08679-3 320 $aIncludes bibliographical references and index. 327 $aDrug metabolism : significance and challenges -- Establishing orphan nuclear receptors PXR and CAR as xenobiotic receptors -- Nuclear receptor-mediated regulation of phase II conjugating enzymes -- Nuclear receptor-mediated regulation of drug transporters -- Structure and function of PXR and CAR -- Xenobiotic receptor cofactors and coregulators -- Animal models of xenobiotic nuclear receptors and their utility in drug development -- Nuclear receptors and drug-drug interactions of prescription drugs and herbal medicines -- Genetic variants of xenobiotic receptors and their implications in drug metabolism and pharmacogenetics -- Beyond PXR and CAR, regulation of xenobiotic metabolism by other nuclear receptors -- Emerging role of retinoid-related orphan receptor (ROR) and its cross talk with LXR (liver X receptor) in the regulation of drug-metabolizing enzymes. 330 $aThis book gives you an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development and equips you with the interdisciplinary understanding of these receptors and how they can be regulated. Pharmaceutical researchers will find this extremely useful in developing drugs for cancer, heart disease, and diabetes treatment. This comprehensive resource collects scattered materials into one handy, informative volume. 606 $aDrugs$xMetabolism 606 $aNuclear receptors (Biochemistry) 606 $aGenetic regulation 615 0$aDrugs$xMetabolism. 615 0$aNuclear receptors (Biochemistry) 615 0$aGenetic regulation. 676 $a615.19 676 $a615/.7 701 $aXie$b Wen$f1967-$01672776 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830085003321 996 $aNuclear receptors in drug metabolism$94036335 997 $aUNINA LEADER 00929nam0 22002773i 450 001 UBO0297789 005 20251003044419.0 010 $a0815514085 100 $a20110617d1996 ||||0itac50 ba 101 | $aeng 102 $aus 181 1$6z01$ai $bxxxe 182 1$6z01$an 200 1 $aIndustrial minerals and their uses$ea handbook and formulary$fedited by Peter A. Ciullo 210 $aWestwood (N.J.)$cNoyes publications$dc1996 215 $aXV, 632 p.$cill.$d24 cm. 676 $a661$9$v22 702 1$aCiullo$b, Peter A.$3UBOV116355 801 3$aIT$bIT-000000$c20110617 850 $aIT-BN0095 901 $bNAP 01$cSALA $n$ 912 $aUBO0297789 950 0$aBiblioteca Centralizzata di Ateneo$d 01SALA 661 IND$e 0104 0000021225 VMA $fA $i20110617 977 $a 01 996 $aIndustrial minerals and their uses$91575559 997 $aUNISANNIO