LEADER 04537nam a2200349Ii 4500 001 991003234919707536 008 070802s2006 ne a sb 001 0 eng d 020 $a9780123705822 020 $a0123705827 035 $ab1365293x-39ule_inst 040 $aBibl. Dip.le Aggr. Ingegneria Innovazione - Sez. Ingegneria Innovazione$beng 082 04$a571.538$222 100 1 $aIkada, Yoshito,$d1935-$0447972 245 10$aTissue engineering$h[e-book] :$bfundamentals and applications /$cYoshito Ikada 260 $aAmsterdam ;$aBoston :$bAcademic Press/Elsevier,$c2006 300 $axix, 469 p. :$bill. (some col.) ;$c25 cm 440 0$aInterface science and technology ;$vv. 8 504 $aIncludes bibliographical references and index 505 0 $aChapter 1: Scope of Tissue Engineering -- 1. Functions of Scaffold -- 2. Absorbable Biomaterials -- 3. Pore Creation in Biomaterials -- 4. Special Scaffolds -- 5. Surface Modifications -- 6. Cell Expansion and Differentiation -- -- 7. Growth Factors -- 8. Cell Sources

-- -- Chapter 2: Animal and Human Trials of Engineered -- Tissues -- 1. Plastic Surgical System -- 2. Musculoskeletal System -- 3. Cardiovascular and Thoracic System -- 4. Nervous System -- 5. Maxillofacial System -- 6. Gastrointestinal System -- -- 7. Urogenital System -- -- 8. Others

-- Chapter 3: Basic Technologies Developed for Tissue Engineering -- 1. Biomaterials -- -- 2. Fabrication of Porous Scaffolds -- 3. Novel Scaffolds -- 4. Surface Modification of Biomaterials and Cell Interactions -- 5. Growth Factors and Carriers -- 6. Cell Culture -- 7. Examples of Cell Culture

-- Chapter 4: Challenges in Tissue Engineering -- 1. Problems in Tissue Engineering -- 2. Sites for Neotissue Creation -- 3. Autologous or Allogeneic Cells -- 4. Cell Types -- 5. Risks at Cell Culture -- 6. Scaffolds for Large Animals and Human Trials -- 7. Importance of Neovascularization -- -- 8. Carriers for Growth Factors -- 9. Primary Roles of Each Player in the Tissue Engineering Arena 520 $aTissue engineering is an emerging interdisciplinary field, occupying a major position in the regenerative medicine that aims at restoring lost or damaged tissues and organs with use of cells. Regenerative medicine includes cellular therapy and tissue engineering. In general, the former treats patients by cell infusion alone, while tissue engineering needs biomaterials and growth factors in addition to cells. Biomaterials function in tissue engineering as the scaffold or template for cells to proliferate, differentiate, and produce matrices. This book focuses on the fundamentals (biomaterials, scaffolds, cell cultures, bioreactors, animal models etc.), recent animal and human trials, and future prospects regarding tissue engineering.

Almost twenty years have passed since the advent of the tissue engineering, whicht uses cells, scaffolds, and growth factors for regeneration of neotissues. The number of investigations on tissue engineering is still increasing tremendously. Nevertheless, it seems likely that the number of reports describing clinical trials of tissue engineering will remain very limited. Even the studies that apply tissue engineering research to large animals have not been performed yet on a large scale. The major objective of this book is to address this question from a science and technology point of view, and to describe the principles of basic technologies that have currently been developed by numerous research groups. * Helps reader understand the key issues required for promotion of clinical trials in tissue engineering * Covers in full the issues related to tissue engineering * Looking at current technologies in the field 533 $aElectronic reproduction.$bAmsterdam :$cElsevier Science & Technology,$d2007.$nMode of access: World Wide Web.$nSystem requirements: Web browser.$nTitle from title screen (viewed on July 25, 2007).$nAccess may be restricted to users at subscribing institutions 650 0$aAnimal cell biotechnology 650 0$aTissue engineering 655 7$aElectronic books.$2local 776 1 $cOriginal$z0123705827$z9780123705822$w(OCoLC)71254946 856 40$3Referex$uhttp://www.sciencedirect.com/science/book/9780123705822$zAn electronic book accessible through the World Wide Web; click for information 907 $a.b1365293x$b03-03-22$c24-01-08 912 $a991003234919707536 994 $aC0$bTEF 996 $aTissue engineering$9103163 997 $aUNISALENTO 998 $ale026$b24-01-08$cm$d@ $e-$feng$gne $h0$i0