LEADER 01503nam a22002891i 4500 001 991002818979707536 005 20040401072622.0 008 040624s1987 it a||||||||||||||||ita 035 $ab12982805-39ule_inst 035 $aARCHE-094048$9ExL 040 $aDip.to Beni Culturali$bita$cA.t.i. Arché s.c.r.l. Pandora Sicilia s.r.l. 082 04$a937.202 245 00$aCelti ed Etruschi nell'Italia centro-settentrionale dal 5. secolo a. C. alla romanizzazione :$batti del colloquio internazionale : Bologna, 12-14 aprile 1985 /$ca cura di Daniele Vitali 260 $aImola :$bUniversity press Bologna,$c[1987] 300 $aXV, 584 p. :$bill. ;$c30 cm 440 0$aRealtà regionale.$pFonti e studi ;$v10 500 $aIn testa al front.: Provincia di Bologna, Assessorato al turismo, Assessorato alla cultura; Camera di commercio di Bologna; Comune di Monterenzio; Universita degli studi di Bologna 650 4$aCONGRESSI$zBologna$y1985 650 4$aEtruschi$zItalia centro-settentrionale$xCongressi$y1985 650 4$aGalli$zItalia centro-settentrionale$xCongressi$y1985 700 1 $aVitali, Daniele 907 $a.b12982805$b02-04-14$c12-07-04 912 $a991002818979707536 945 $aLE001 AR XIII 114$g1$i2001000074990$lle001$nC. 1$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i13587122$z12-07-04 996 $aCelti ed Etruschi nell'Italia centro-settentrionale dal 5. secolo a. 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Gilbert 210 1$aAmsterdam, [Netherlands] :$cAcademic Press,$d2016. 210 4$d©2016 215 $a1 online resource (504 p.) 300 $aDescription based upon print version of record. 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aFront Cover; PEDIATRIC BRAIN STIMULATION; How to Use; PEDIATRIC BRAIN STIMULATION; Copyright; Contents; List of Contributors; Foreword; Preface; I - FUNDAMENTALS OF NIBS IN CHILDREN; 1 - TMS Basics: Single and Paired Pulse Neurophysiology; INTRODUCTION; HOW DOES TMS WORK?; Principle of TMS; Types of TMS Coil; NEURONAL STRUCTURES ACTIVATED BY TMS; Stimulation of the Motor Cortex; Descending Volleys; Descending Pathways from the Cerebral Cortex; Motor-Evoked Potential; Motor Thresholds; TMS NEUROPHYSIOLOGY; Single-Pulse TMS; Stimulus Response Curve; Silent Periods; Paired-pulse TMS 327 $aShort-Interval Intercortical Inhibition (SICI)Intracortical Facilitation (ICF); Short-Interval Intracortical Facilitation (SICF); Long-Interval Intracortical Inhibition (LICI); Interhemispheric Inhibition (IHI); TMS Paired With Sensory Activation; Short-Latency Afferent Inhibition (SAI); Paired Associative Stimulation (PAS); Repetitive TMS; TMS RELIABILITY; TMS SAFETY; References; 2 - Assessing Normal Developmental Neurobiology With Brain Stimulation; INTRODUCTION; NORMAL DEVELOPMENTAL NEUROBIOLOGY; Theoretical Background of Excessive Production of Synapses/Pruning of Synaptic Connectivity 606 $aBrain stimulation$xTherapeutic use 606 $aMental Disorders$xtherapy 606 $aBrain Diseases$xtherapy 606 $aElectric Stimulation Therapy 606 $aTranscranial Magnetic Stimulation 615 0$aBrain stimulation$xTherapeutic use. 615 12$aMental Disorders$xtherapy. 615 22$aBrain Diseases$xtherapy. 615 22$aElectric Stimulation Therapy. 615 22$aTranscranial Magnetic Stimulation. 676 $a616.804645 702 $aKirton$b Adam 702 $aGilbert$b Donald L. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910824273503321 996 $aPediatric brain stimulation$93991990 997 $aUNINA LEADER 03215nam 2200421z- 450 001 9910227348503321 005 20210212 035 $a(CKB)4100000000883848 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/61064 035 $a(oapen)doab61064 035 $a(EXLCZ)994100000000883848 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aTox21 Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Toxicants and Drugs 210 $cFrontiers Media SA$d2017 215 $a1 online resource (102 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-197-6 330 $aTens of thousands of chemicals are released into the environment every day. High-throughput screening (HTS) has offered a more efficient and cost-effective alternative to traditional toxicity tests that can profile these chemicals for potential adverse effects with the aim to prioritize a manageable number for more in depth testing and to provide clues to mechanism of toxicity. The Tox21 program, a collaboration between the National Institute of Environmental Health Sciences (NIEHS)/National Toxicology Program (NTP), the U.S. Environmental Protection Agency's (EPA) National Center for Computational Toxicology (NCCT), the National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS), and the U.S. Food and Drug Administration (FDA), has generated quantitative high-throughput screening (qHTS) data on a library of 10K compounds, including environmental chemicals and drugs, against a panel of nuclear receptor and stress response pathway assays during its production phase (phase II). The Tox21 Challenge, a worldwide modeling competition, was launched that asks a "crowd" of researchers to use these data to elucidate the extent to which the interference of biochemical and cellular pathways by compounds can be inferred from chemical structure data. In the Challenge participants were asked to model twelve assays related to nuclear receptor and stress response pathways using the data generated against the Tox21 10K compound library as the training set. The computational models built within this Challenge are expected to improve the community's ability to prioritize novel chemicals with respect to potential concern to human health. This research topic presents the resulting computational models with good predictive performance from this Challenge. 606 $aEnvironmental economics$2bicssc 610 $aHTS 610 $ain vitro assay 610 $anuclear receptor 610 $apredictive model 610 $aQSAR 610 $astress response 610 $aTox21 615 7$aEnvironmental economics 700 $aXia$b Menghang$4auth$01838548 702 $aRuili Huang$4auth 906 $aBOOK 912 $a9910227348503321 996 $aTox21 Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Toxicants and Drugs$94417534 997 $aUNINA