LEADER 02703nam 2200601Ia 450 001 9910144137403321 005 20221206105106.0 010 $a0-470-43856-8 010 $a1-281-73255-9 010 $a9786611732554 010 $a0-470-36871-3 010 $a0-470-36997-3 035 $a(CKB)1000000000537144 035 $a(EBL)353559 035 $a(OCoLC)476175332 035 $a(SSID)ssj0000123014 035 $a(PQKBManifestationID)11141217 035 $a(PQKBTitleCode)TC0000123014 035 $a(PQKBWorkID)10131343 035 $a(PQKB)10661837 035 $a(MiAaPQ)EBC353559 035 $a(MiAaPQ)EBC4025424 035 $a(EXLCZ)991000000000537144 100 $a20080110d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aClassical and adaptive clinical trial designs using ExpDesign Studio [trademark symbol]$b[electronic resource] /$fMark Chang 210 $aHoboken, N.J. $cJohn Wiley$dc2008 215 $a1 online resource (280 p.) 300 $aDescription based upon print version of record. 311 $a0-470-27612-6 320 $aIncludes bibliographical references and index. 327 $aExpDesign Studio -- Clinical trial design -- Classical trial design -- Group sequential trial design -- Adaptive trial design -- Adaptive trial monitoring -- Oncology adaptive trial design -- Adaptive trial simulator -- Further assistance from ExpDesign Studio. 330 $aExpDesign Studio facilitates more efficient clinical trial design This book introduces pharmaceutical statisticians, scientists, researchers, and others to ExpDesign Studio software for classical and adaptive designs of clinical trials. It includes the Professional Version 5.0 of ExpDesign Studio software that frees pharmaceutical professionals to focus on drug development and related challenges while the software handles the essential calculations and computations. After a hands-on introduction to the software and an overview of clinical trial designs encompassing numerous variations 606 $aDrugs$xTesting$xComputer simulation 606 $aAdaptive sampling (Statistics) 606 $aClinical trials$xData processing 615 0$aDrugs$xTesting$xComputer simulation. 615 0$aAdaptive sampling (Statistics) 615 0$aClinical trials$xData processing. 676 $a615.50724 676 $a615/.190113 700 $aChang$b Mark$0520702 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144137403321 996 $aClassical and adaptive clinical trial designs using ExpDesign Studio$92139729 997 $aUNINA LEADER 01408nam a2200325 i 4500 001 991002474729707536 005 20250215134506.0 008 000531s1976 it a er |01 0 ita 035 $ab11014878-39ule_inst 035 $aPARLA163280$9ExL 040 $aDip.to Scienze Storiche Fil. e Geogr.$bita$dSocioculturale Scs 041 0 $aita 082 04$a945.753$223 100 1 $aCaggia, Carlo$0445998 245 10$aCronache fra due secoli :$blotte politiche e sociali dal 1896 al 1909 in una citta del Salento attraverso la stampa socialista /$cCarlo Caggia ; introduzione di Aldo Vallone 260 $aGalatina :$bCongedo,$c1976 300 $a177 p. :$bill. ;$c21 cm 490 1 $aL'altro Sud ;$v2 650 4$aSocialismo$zGalatina$y1896-1909 651 4$aGalatina$xStoria$y1896-1909 700 1 $aVallone, Aldo 830 2$aL'altro Sud ;$v2 907 $a.b11014878$b21-09-06$c28-06-02 912 $a991002474729707536 945 $aLE002 Sal. IV C 14$g1$i2002000986580$lle002$o-$pE0.00$q-$rn$so$t0$u0$v0$w0$x0$y.i10408484$z27-06-02 945 $aLE009 STOR.07.1-22$g1$i2009000038462$lle009$o-$pE0.00$q-$rl$s-$t0$u1$v0$w1$x0$y.i11133326$z28-06-02 945 $aLE009 STOR.07.1-22BIS$g2$i2009000350151$lle009$o-$pE0.00$q-$rl$s-$t0$u0$v0$w0$x0$y.i13250905$z05-04-04 996 $aCronache fra due secoli$998118 997 $aUNISALENTO 998 $ale002$a(2)le009$b01-01-00$cm$da$e-$fita$git$h0$i3 LEADER 03776nam 2200697Ia 450 001 9910972649703321 005 20200520144314.0 010 $a9786612312274 010 $a9781282312272 010 $a1282312278 010 $a9789027289346 010 $a9027289344 024 7 $a10.1075/la.145 035 $a(CKB)1000000000799559 035 $a(OCoLC)649900848 035 $a(CaPaEBR)ebrary10335313 035 $a(SSID)ssj0000287883 035 $a(PQKBManifestationID)11192856 035 $a(PQKBTitleCode)TC0000287883 035 $a(PQKBWorkID)10371995 035 $a(PQKB)11264152 035 $a(MiAaPQ)EBC622207 035 $a(Au-PeEL)EBL622207 035 $a(CaPaEBR)ebr10335313 035 $a(CaONFJC)MIL231227 035 $a(OCoLC)492092539 035 $a(DE-B1597)720902 035 $a(DE-B1597)9789027289346 035 $a(EXLCZ)991000000000799559 100 $a20090318d2009 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe acquisition of word order $emicro-cues, information structure, and economy /$fMarit Westergaard 205 $a1st ed. 210 $aPhiladelphia, PA ;$aAmsterdam $cJohn Benjamins Pub. Company$dc2009 215 $a1 online resource (xii, 245 pages) $cillustrations 225 0 $aLinguistik aktuell/linguistics today,$x0166-0829 ;$vv. 145 300 $aBibliographic Level Mode of Issuance: Monograph 311 0 $a9789027255280 311 0 $a9027255288 320 $aIncludes bibliographical references and index. 327 $aAcknowledgements -- Preliminaries -- Word order variation and the structure of the target language -- The syntax of V2 and a model of micro-cues -- The input -- The acquisition of word order in non-subject-initial declaratives -- The acquisition of word order in subject-initial declaratives -- The acquisition of word order in wh-questions -- The acquisition of word order in yes/no-questions -- The acquisition of word order in non-V2 contexts -- Micro-cues, information structure, and economy -- References -- Appendix -- Index. 330 $aWithin a new model of language acquisition, this book discusses verb second (V2) word order in situations where there is variation in the input. While traditional generative accounts consider V2 to be a parameter, this study shows that, in many languages, this word order is dependent on fine distinctions in syntax and information structure. Thus, within a split-CP model of clause structure, a number of micro-cues are formulated, taking into account the specific context for V2 vs. non-V2 (clause type, subcategory of the elements involved, etc.). The micro-cues are produced in children's I-language grammars on exposure to the relevant input. Focusing on a dialect of Norwegian, the book shows that children generally produce target-consistent V2 and non-V2 from early on, indicating that they are sensitive to the micro-cues. This includes contexts where word order is dependent on information structure. The children's occasional non-target-consistent behavior is accounted for by economy principles. 606 $aNorwegian language$xWord order 606 $aNorwegian language$xAcquisition 606 $aGrammar, Comparative and general$xWord order 615 0$aNorwegian language$xWord order. 615 0$aNorwegian language$xAcquisition. 615 0$aGrammar, Comparative and general$xWord order. 676 $a439.8/282421 700 $aWestergaard$b Marit R$g(Marit Richardsen)$01800261 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910972649703321 996 $aThe acquisition of word order$94344974 997 $aUNINA