LEADER 02242nam 2200397 450 001 9910583354703321 005 20180710153856.0 010 $a0-12-809856-2 035 $a(CKB)4340000000208900 035 $a(MiAaPQ)EBC5106110 035 $a(PPN)228029872 035 $a(EXLCZ)994340000000208900 100 $a20171117h20182018 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aGERD $ea new understanding of pathology, pathophysiology, and treatment /$fParakrama T. Chandrasoma 210 1$aLondon, England :$cAcademic Press,$d2018. 210 4$dİ2018 215 $a1 online resource (654 pages) $cillustrations (some color) 311 $a0-12-809855-4 320 $aIncludes bibliographical references at the end of each chapters and indexes. 327 $aDefinition of gastroesophageal reflux disease -- Present diagnosis and management of gastroesophageal and reflux disease -- Fetal and postnatal development of the esophagus and proximal stomach -- Histologic definition and diagnosis of epithelia in the esophagus and proximal stomach -- Definition of the normal state -- Definition of the gastroesophageal junction -- The normal lower esophageal sphincter -- The pathogenesis of early GERD -- Correlation of LES damage and GERD -- The effect of damage to the abdominal segement of the LES -- Columnar-lined esophagus -- Esophageal adenocarcinoma -- Progression of GERD at the clinical level -- Progression of GERD at a pathological level -- Molecular evolution of esophageal epithelial metaplasia -- Progression of GERD from the perspective of LES damage -- New pathologic test of LES damage -- New method of functional assessment of the LES -- Prediction of future progression of LES damage -- Proof of cencept of the new diagnostic method -- Application of the new method to present and future management of GERD. 606 $aGastroesophageal reflux 615 0$aGastroesophageal reflux. 676 $a616.324 700 $aChandrasoma$b Para$0932152 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910583354703321 996 $aGERD$92096921 997 $aUNINA LEADER 01142nas a2200289 i 4500 001 991002469839707536 005 20231114121139.0 008 011205m19959999 m| 0 |eng d 022 $a0947-8396$l1432-0630 035 $ab11664630-39ule_inst 035 $aocm00000006$9ExL 222 0$aApplied physics. A :$bMaterials science & processing 245 00$aApplied physics. A :$bMaterials science & processing /$cAmerican Institute of Physics. - 1995- 260 $aBerlin,$c1995- 500 $aPubblicato anche in formato elettronico 591 $aCodice CNR: P 00200001 592 $aLE006 1995-2008; lac.: 2001;2008; 710 2 $aAIP 776 1 $nISSN (electronic edition):$x1432-0630 780 00$tApplied physics. A$bSolids and surfaces 856 41$uhttp://link.springer.com/journal/339$zE-journal (Publisher Site) 907 $a.b11664630$b01-10-18$c08-07-02 912 $a991002469839707536 945 $aLE006$g1$lle006$o-$pE0.00$q-$rn$so$t18$u0$v0$w0$x0$y.i11888271$z08-07-02 996 $aApplied physics. A$9240397 997 $aUNISALENTO 998 $ale006$b01-01-01$cs$da$e-$feng$ggw$h0$i1