LEADER 00985nam a2200277 i 4500 001 991002302459707536 005 20020507162403.0 008 000117s1991 it ||| | ita 020 $a8813172753 035 $ab11637651-39ule_inst 035 $aLE02734216$9ExL 040 $aDip.to Studi Giuridici$bita 082 0 $a340 084 $aC-XX/C 100 1 $aAccardo, Anna$0232957 245 13$aLa scuola :$bdiritto, problematiche, prospettive /$cAnna Accardo 260 $aPadova :$bCEDAM,$c1991 300 $aix, 288 p. ;$c24 cm. 650 4$aScuola - Legilazione 907 $a.b11637651$b21-09-06$c02-07-02 912 $a991002302459707536 945 $aLE027 340.00 ACC01.01$g1$i2027000001842$lle027$o-$pE0.00$q-$rl$s- $t0$u1$v0$w1$x0$y.i11859155$z02-07-02 945 $aLE027 C-XX/C 2$g1$iLE027I-205$lle027$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i11859167$z02-07-02 996 $aScuola$9877405 997 $aUNISALENTO 998 $ale027$b01-01-00$cm$da $e-$fita$git $h3$i2 LEADER 04046nam 22005895 450 001 9910300273303321 005 20251116195422.0 010 $a9783319724225 010 $a3319724223 024 7 $a10.1007/978-3-319-72422-5 035 $a(CKB)4100000002892190 035 $a(MiAaPQ)EBC5345462 035 $a(DE-He213)978-3-319-72422-5 035 $a(PPN)225547554 035 $a(EXLCZ)994100000002892190 100 $a20180305d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDrug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions /$fedited by Manjunath P. Pai, Jennifer J. Kiser, Paul O. Gubbins, Keith A. Rodvold 205 $a4th ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2018. 215 $a1 online resource (336 pages) 225 1 $aInfectious Disease 311 08$a9783319724218 311 08$a3319724215 327 $aIntroduction to Drug-Drug Interactions -- Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion -- Mechanisms of Drug Interactions II: Transport Proteins -- Drug-Food Interactions -- Drug-Cytokine Interactions -- Interactions between Herbs and Antiinfective Medications -- In vitro Modeling of Drug-Drug Interactions -- Probe Cocktail Studies -- Design and Data Analysis in Drug Interaction Studies. 330 $aThe 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes ? ?Mechanisms and Models of Drug Interactions? and ?Antimicrobial Drug Interactions?. This volume, ?Mechanisms and Models of Drug Interactions,? delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development. 410 0$aInfectious Disease 606 $aPharmaceutical technology 606 $aInfectious diseases 606 $aPharmacy 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aPharmacy$3https://scigraph.springernature.com/ontologies/product-market-codes/F00008 615 0$aPharmaceutical technology. 615 0$aInfectious diseases. 615 0$aPharmacy. 615 14$aPharmaceutical Sciences/Technology. 615 24$aInfectious Diseases. 615 24$aPharmacy. 676 $a615.7045 702 $aPai$b Manjunath P.$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKiser$b Jennifer J$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGubbins$b Paul O$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRodvold$b Keith$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300273303321 996 $aDrug Interactions in Infectious Diseases$91745060 997 $aUNINA