LEADER 01197nam a22002771i 4500 001 991001906229707536 005 20040105152105.0 008 040407m19761981it |||||||||||||||||ita 035 $ab12841316-39ule_inst 035 $aARCHE-082093$9ExL 040 $aDip.to Scienze Storiche$bita$cA.t.i. Arché s.c.r.l. Pandora Sicilia s.r.l. 082 04$a727.6509 245 02$aI musei scientifici a Firenze :$bproblemi di restauro e ricomposizione museale /$ca cura di Francesco Gurrieri e Luigi Zangheri 260 $aFirenze :$bUNIEDIT :$b[poi] Alinea,$c1976-1981 300 $a2 v. ;$c21 cm 500 $aScritti di vari. 651 4$aFirenze$xCollezioni scientifiche$xRestauro 700 1 $aZangheri, Luigi 700 1 $aGurrieri, Francesco 907 $a.b12841316$b02-04-14$c16-04-04 912 $a991001906229707536 945 $aLE009 LA VII D 6 $cV. 1$g1$iLE009A-01817/1 LA$lle009$o-$pE0.00$q-$rn$so $t0$u0$v0$w0$x0$y.i13395154$z16-04-04 945 $aLE009 LA VII D 6/1$cV. 2$g1$iLE009A-01817 LA$lle009$o-$pE0.00$q-$rn$so $t0$u0$v0$w0$x0$y.i13395166$z16-04-04 996 $aMusei scientifici a Firenze$9298023 997 $aUNISALENTO 998 $ale009$b16-04-04$cm$da $e-$fita$git $h2$i2 LEADER 05182nam 22006254a 450 001 9910830736603321 005 20230721025854.0 010 $a1-280-72225-8 010 $a9786610722259 010 $a0-470-08012-4 010 $a0-470-08011-6 035 $a(CKB)1000000000355237 035 $a(EBL)281572 035 $a(OCoLC)636860304 035 $a(SSID)ssj0000112107 035 $a(PQKBManifestationID)11142574 035 $a(PQKBTitleCode)TC0000112107 035 $a(PQKBWorkID)10087219 035 $a(PQKB)11393200 035 $a(MiAaPQ)EBC281572 035 $a(EXLCZ)991000000000355237 100 $a20060505d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiomacromolecules$b[electronic resource] $eintroduction to structure, function and informatics /$fC. Stan Tsai 210 $aHoboken, N.J. $cWiley-Liss$dc2007 215 $a1 online resource (770 p.) 300 $aDescription based upon print version of record. 311 $a0-471-71397-X 320 $aIncludes bibliographical references and index. 327 $aBIOMACROMOLECULES; CONTENTS; Preface; Abbreviations in Repetitive Use; CHAPTER 1 INTRODUCTION; 1.1 Prelude; 1.2 Covalent Bonds; 1.3 Noncovalent Interactions; 1.3.1 Electrostatic Interaction; 1.3.2 Van der Waals Interaction; 1.3.3 Hydrogen Bond; 1.3.4 Hydrophobic Interaction; 1.3.5 Steric Repulsion; 1.4 Isomerism: Configuration versus Conformation; 1.5 Trilogy; 1.6 References; CHAPTER 2 MONOMER CONSTITUENTS OF BIOMACROMOLECULES; 2.1 Nucleotides: Constituents of Nucleic Acids; 2.2 ?-Amino Acids: Constituents of Proteins; 2.3 Monosaccharides: Constituents of Glycans; 2.4 Addendum; 2.5 References 327 $aCHAPTER 3 PURIFICATION AND CHARACTERIZATION3.1 Purification: Overview; 3.2 Purification: Chromatography; 3.3 Purification: Electrophoresis; 3.4 Characterization: General; 3.4.1 Purity; 3.4.2 Molecular Weight; 3.4.3 Molecular Dimension; 3.5 Characterization: Specific; 3.5.1 Melting Temperature of DNA; 3.5.2 Buoyant Density of Biomacromolecules; 3.5.3 Isoelectric pH of Proteins; 3.5.4 Removal of Glycosides from Glycoproteins; 3.6 References; CHAPTER 4 BIOMACROMOLECULAR STRUCTURE: NUCLEIC ACIDS; 4.1 Structural Organization; 4.1.1 Structural Hierarchy 327 $a4.1.2 Representation of Structures of Nucleic Acids4.2 Sequence Analysis of Nucleic Acids; 4.2.1 General; 4.2.2 Chemical Cleavage Method; 4.2.3 Enzymatic Chain Termination/Dideoxy Method; 4.2.4 Mass Spectrometric Analysis; 4.2.5 Automated DNA Sequencing Technology; 4.3 Secondary Structure and Structure Polymorphism of DNA; 4.3.1 Key Structural Features of Nucleic Acids; 4.3.2 DNA Polymorphism; 4.3.3 Alternative Structures of DNA; 4.4 Supercoiling and Tertiary Structure of DNA; 4.4.1 DNA Topoisomers; 4.4.2 Superhelical Density and Energetics of Supercoiling. 327 $a4.5 Classification and Structures of RNA4.5.1 Structures of RNA; 4.5.2 Transfer RNA; 4.5.3 Ribosomal RNA; 4.5.4 Messenger RNA; 4.5.5 Other Classes of RNA; 4.6 RNA Folds and Structure Motifs; 4.6.1 RNA Folds; 4.6.2 Structure Motifs of RNA; 4.7 Energetics of Nucleic Acid Structure; 4.8 Nucleic Acid Application; 4.9 References; CHAPTER 5 BIOMACROMOLECULAR STRUCTURE: PROTEINS; 5.1 Architecture of Protein Molecules; 5.1.1 Introduction; 5.1.2 Representation of Protein Structures; 5.2 Primary Structure of Proteins: Chemical and Enzymatic Sequence Analysis; 5.2.1 Amino Acid Composition 327 $a5.2.2 Peptide Cleavage, Separation and Analysis5.2.3 Terminal and Sequence Determination; 5.2.4 Peptide Ladder Sequencing; 5.3 Primary Structure of Proteins: Sequence Analysis by Tandem Mass Spectrometry; 5.3.1 An Application of Mass Spectrometry (MS) in Protein Chemistry; 5.3.2 Application of Tandem Mass Spectrometry (MS-MS) in Protein Sequence Analysis; 5.4 Conformational Map; 5.5 Secondary Structures and Motifs of Proteins; 5.5.1 ?-Helical Structure; 5.5.2 ?-Sheet Structure; 5.5.3 Nonrepetitive Structure: Connection (Loop) and Turn; 5.5.4 Notes to Secondary Structures of Globular Proteins 327 $a5.5.5 Motifs: Supersecondary Structures 330 $aThis book provides an integrated treatment of the structure and function of nucleic acids, proteins, and glycans, including thorough coverage of relevant computational biochemistry. The text begins with an introduction to the biomacromolecules, followed by discussion of methods of isolation and purification, physiochemical and biochemical properties, and structural characteristics. The next section of the book deals with sequence analysis, analysis of conformation using spectroscopy, chemical synthesis, and computational approaches. The following chapters discuss biomolecular interactions, e 606 $aMacromolecules 606 $aBiomolecules 615 0$aMacromolecules. 615 0$aBiomolecules. 676 $a572 676 $a572.8 676 $a572/.33 700 $aTsai$b C. Stan$01593276 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830736603321 996 $aBiomacromolecules$93913333 997 $aUNINA