LEADER 01191nam a2200301 i 4500 001 991001515849707536 005 20020503122436.0 008 991018s1983 uk ||| | eng 020 $a0333334132 035 $ab10231845-39ule_inst 035 $aLE01279109$9ExL 040 $aDip.to Lingue$bita 100 1 $aSpindler, Michael$0464919 245 10$aAmerican literature and social change :$bWilliam Dean Howells to Arthur Miller /$cMichael Spindler 260 $aLondon, Basingstoke :$bMacMillan Press LTD,$cc1983 300 $aviii,236 p. ;$c23 cm. 500 $aIncludes bibliographical references and index 650 4$aCapitalismo industriale nella letteratura 650 4$aEconomia nella letteratura 650 4$aIndustrie nella letteratura 650 4$aLetteratura americana$xStoria e critica 650 4$aProblemi sociali nella letteratura 907 $a.b10231845$b21-09-06$c27-06-02 912 $a991001515849707536 945 $aLE012 810.9 SPI$g1$i2012000012097$lle012$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i10281605$z27-06-02 996 $aAmerican literature and social change$9207413 997 $aUNISALENTO 998 $ale012$b01-01-99$cm$da $e-$feng$guk $h0$i1 LEADER 02783nam 2200481z- 450 001 9910166646403321 005 20210211 035 $a(CKB)3710000001092135 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42856 035 $a(oapen)doab42856 035 $a(EXLCZ)993710000001092135 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aCell Fate 210 $cFrontiers Media SA$d2016 215 $a1 online resource (102 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-852-9 330 $aThe fundamental question of how an undifferentiated progenitor cell adopts a more specialized cell fate that then contributes to the development of specialized tissues, organs, organ systems and ultimately a unique individual of a given species has intrigued cell and developmental biologists for many years. Advances in molecular and cell biology have enabled investigators to identify genetic and epigenetic factors that contribute to these processes with increasing detail and also to define the various molecular characteristics of each cell fate with greater precision. Understanding these processes have also provided greater insights into disorders in which the normal mechanisms of cell fate determination are altered, such as in cancer and inherited malformations. With these advances have come techniques that facilitate the manipulation of cell fate, which have the potential to revolutionize the field of medicine by facilitating the repair and/or regeneration of diseased organs. Given the rapid advances that are occurring in the field, the articles in this eBook are both relevant and timely. These articles originally appeared online as part of the Research Topic "Cell Fate" overseen by my colleagues Dr. Lin, Dr. Buttitta, Dr. Maves, Dr. Dilworth, Dr. Paladini and myself and have been viewed extensively. Because of their popularity, they are now made available as an eBook, in a more easily downloadable form. Michael T. Chin 606 $aGenetics (non-medical)$2bicssc 610 $aCell Cycle 610 $acell fate 610 $aChromatin 610 $aepigenetics 610 $agene regulation 610 $anuclear architecture 610 $astem cell 610 $aTranscription Factors 615 7$aGenetics (non-medical) 700 $aChin-Hsing Annie Lin$4auth$01277587 702 $aLisa Maves$4auth 702 $aMichael T. Chin$4auth 702 $aLaura Buttitta$4auth 702 $aF. Jeffrey Dilworth$4auth 702 $aCarlos A. Paladini$4auth 906 $aBOOK 912 $a9910166646403321 996 $aCell Fate$93011673 997 $aUNINA