LEADER 01217nam a2200361 i 4500 001 991001082479707536 005 20020507182936.0 008 961204s1988 us ||| | eng 020 $a0940600137 035 $ab10798481-39ule_inst 035 $aLE01306757$9ExL 040 $aDip.to Matematica$beng 082 0 $a519.5 084 $aAMS 62A10 084 $aAMS 62A15 084 $aAMS 62A20 100 1 $aBerger, James O.$054427 245 14$aThe likelihood principle /$cJames O. Berger, Robert L. Wolpert 250 $a2nd ed 260 $aHayward, Calif :$bIMS (Institute of Mathematical Statistics),$cc1988 300 $axii, 208 p. ;$c26 cm. 490 0 $aLecture notes-monograph series ;$v6 500 $aIncludes bibliographies and indexes 650 4$aEstimation theory 650 4$aMathematical statistics 650 4$aProbabilities 700 1 $aWolpert, Robert L. 907 $a.b10798481$b23-02-17$c28-06-02 912 $a991001082479707536 945 $aLE013 62A BER21 (1988)$g1$i2013000080048$lle013$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i10902156$z28-06-02 996 $aLikelihood principle$9921654 997 $aUNISALENTO 998 $ale013$b01-01-96$cm$da $e-$feng$gus $h4$i1 LEADER 04517nam 22005535 450 001 9910616362303321 005 20251009102856.0 010 $a9783031092220 010 $a3-031-09222-8 024 7 $a10.1007/978-3-031-09222-0 035 $a(MiAaPQ)EBC7107414 035 $a(Au-PeEL)EBL7107414 035 $a(CKB)24995984800041 035 $a(PPN)265861810 035 $a(DE-He213)978-3-031-09222-0 035 $a(OCoLC)1347019344 035 $a(EXLCZ)9924995984800041 100 $a20221005d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDermal Absorption and Decontamination $eA Comprehensive Guide /$fedited by Aileen M. Feschuk, Rebecca M. Law, Howard I. Maibach 205 $a1st ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022. 215 $a1 online resource (339 pages) 225 1 $aMedicine Series 311 08$aPrint version: Feschuk, Aileen M. Dermal Absorption and Decontamination Cham : Springer International Publishing AG,c2022 9783031092213 320 $aIncludes bibliographical references and index. 327 $aSkin Decontamination with Water: Evidence from In Vivo Human Studies -- Towards a harmonized protocol for in vitro human skin decontamination efficacy -- In Vitro Human Skin Decontamination with Water: Chemical Warfare Agents or Simulants -- In Vitro Human Skin Decontamination with Water: Occupational Contaminants -- Skin Decontamination with Water: Evidence from In Vivo Animal Models -- Skin Decontamination with Water: Evidence from In Vitro Animal Models -- Dry Decontamination with Readily Available Products -- A Review of Reactive Skin Decontamination Lotion Efficacy -- Aqueous suspensions of Fuller?s earth potentiate the adsorption capacities of Paraoxon and improve skin decontamination properties -- Development of a next generation military skin decontaminant: Initial efficacy studies of Zirconium Hydroxide -- Findings from the PHOENIX project: ?Protocols for Hair and the Optimisation of Existing and Novel decontamination Interventions through experimentation -- Twenty clinically pertinent factors/ observations for percutaneous absorption in humans -- Lateral Spread and Percutaneous Penetration: An Overview -- Regional Variation in Percutaneous Absorption: Evidence from In Vitro Human Models -- Experimental Variability in TEWL Data -- Relationships Between Skin of Color and the TEWL Barrier . 330 $aThis book is a comprehensive volume dedicated to dermal absorption and decontamination. Given risks including chemical warfare and accidents with toxic industrial chemicals, studies involving dermal absorption and decontamination are of the utmost importance. Each chapter consists of a systematic review on an important dermal absorption and/or decontamination topic. Chapters address key issues such as the general acceptance of water/ soap and water as the gold standard of dermal decontamination despite the fact that it commonly provides incomplete decontamination and may even result in a ?wash-in effect? (an increased penetration of contaminant). Decontamination with other substances (e.g. RSDL) is explored, and factors that affect dermal penetration (e.g. anatomical variation) are summarized. All systematic reviews are comprehensive and up-to-date. Dermal Absorption and Decontamination will be useful for many fields and disciplines. Firstly, information on dermal decontamination may be used by governments for military and national defense purposes in the event of chemical warfare. Additionally, this information would be of use to many production companies, whose employees are at risk of an accident with toxic industrial chemicals. Topics covered in the book will also be of use to pharmaceutical companies, especially those exploring transdermal delivery of drugs and is of great relevance to those in the medical field, particularly dermatologists. 410 0$aMedicine Series 606 $aDermatology 606 $aDermatology 615 0$aDermatology. 615 14$aDermatology. 676 $a733 676 $a616.5 702 $aFeschuk$b Aileen M. 702 $aLaw$b Rebecca M. 702 $aMaibach$b Howard I. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910616362303321 996 $aDermal absorption and decontamination$93044769 997 $aUNINA