LEADER 00951nam a2200253 i 4500 001 991000538149707536 008 041106s1967 it a 001 0 ita d 035 $ab1323562x-39ule_inst 040 $aDip.to Beni Culturali$bita 100 1 $aCamporeale, Giovannangelo.$0185358 245 13$aLa tomba del duce. 260 $aFirenze :$bL. S. Olschki,$c1967. 300 $a179 p., XLII tav ;$bill. ;$c31 cm. 440 0$aVetulonia ;$v1 440 0$aMonumenti etruschi ;$v1 500 $aIn testa al front.: Istituto di studi etruschi ed italici. 651 4$aVetulonia (Italia)$xTombe 710 2 $aIstituto di studi etruschi ed italici. 907 $a.b1323562x$b21-09-06$c06-11-04 912 $a991000538149707536 945 $aLE001 AR XIII 80$g1$i2001000144556$lle001$nCambio$oe$pE20.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i13917821$z06-11-04 996 $aTomba del Duce$9590738 997 $aUNISALENTO 998 $ale001$b06-11-04$cm$da $e-$fita$git $h0$i0 LEADER 05460nam 2200793Ia 450 001 9910970630703321 005 20200520144314.0 010 $a9786612537929 010 $a9781282537927 010 $a128253792X 010 $a9780226857480 010 $a0226857484 024 7 $a10.7208/9780226857480 035 $a(CKB)2520000000006493 035 $a(EBL)496640 035 $a(OCoLC)609650003 035 $a(SSID)ssj0000365943 035 $a(PQKBManifestationID)12090851 035 $a(PQKBTitleCode)TC0000365943 035 $a(PQKBWorkID)10414226 035 $a(PQKB)10294580 035 $a(StDuBDS)EDZ0000122536 035 $a(MiAaPQ)EBC496640 035 $a(DE-B1597)524584 035 $a(DE-B1597)9780226857480 035 $a(Au-PeEL)EBL496640 035 $a(CaPaEBR)ebr10372060 035 $a(CaONFJC)MIL253792 035 $a(Perlego)1852088 035 $a(EXLCZ)992520000000006493 100 $a20020117d2002 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSmoke-filled rooms $ea postmortem on the tobacco deal /$fW. Kip Viscusi 205 $a1st ed. 210 $aChicago $cUniversity of Chicago Press$d2002 215 $a1 online resource (273 p.) 225 1 $aStudies in law and economics 300 $aDescription based upon print version of record. 311 08$a9780226857473 311 08$a0226857476 320 $aIncludes bibliographical references (p. 243-252) and index. 327 $tFrontmatter -- $tContents -- $tAcknowledgments -- $tI. Introduction -- $tII. The Proposed Federal Settlement -- $tIII. The Settlement of the State Lawsuits -- $tIV. The Financial Costs of Smoking to Society -- $tV. The Financial Costs to the States and the Federal Government -- $tVI. Environmental Tobacco Smoke -- $tVII. Risk Beliefs and Addiction -- $tVIII. Youth Smoking: Beyond Joe Camel -- $tIX. Promoting Safer Cigarettes -- $tX. Lessons from the Tobacco Deal -- $tNotes -- $tReferences -- $tIndex 330 $aThe 1998 out-of-court settlements of litigation by the states against the cigarette industry totaled $243 billion, making it the largest payoff ever in our civil justice system. Two key questions drove the lawsuits and the attendant settlement: Do smokers understand the risks of smoking? And does smoking impose net financial costs on the states? With Smoke-Filled Rooms,W. Kip Viscusi provides unexpected answers to these questions, drawing on an impressive range of data on several topics central to the smoking policy debate. Based on surveys of smokers in the United States and Spain, for instance, he demonstrates that smokers actually overestimate the dangers of smoking, indicating that they are well aware of the risks involved in their choice to smoke. And while smoking does increase medical costs to the states, Viscusi finds that these costs are more than financially balanced by the premature mortality of smokers, which reduces their demands on state pension and health programs, so that, on average, smoking either pays for itself or generates revenues for the states. Viscusi's eye-opening assessment of the tobacco lawsuits also includes policy recommendations that could frame these debates in a more productive way, such as his suggestion that the FDA should develop a rating system for cigarettes and other tobacco products based on their relative safety, thus providing an incentive for tobacco manufacturers to compete among themselves to produce safer cigarettes. Viscusi's hard look at the facts of smoking and its costs runs against conventional thinking. But it is also necessary for an informed and realistic debate about the legal, financial, and social consequences of the tobacco lawsuits. People making $50,000 or more pay .08 percent of their income in cigarette taxes, but people with incomes of less than $10,000 pay 1.62 percenttwenty times as much. The maintenance crew at the Capitol will bear more of the "sin tax" levied on cigarettes than will members of Congress who voted to boost it. Cigarettes are not a financial drain to the U.S. In fact, they are self-financing, as a consequence of smokers' premature mortality. The general public estimates that 47 out of 100 smokers will die from lung cancer because they smoke. Smokers believe that 40 out of 100 will die of the disease. Scientists estimate the actual number of 100 smokers who will die from lung cancer to be between 7 and 13. 410 0$aStudies in law and economics (Chicago, Ill.) 606 $aTobacco industry$xGovernment policy$zUnited States 606 $aCigarette industry$zUnited States 606 $aCigarette smoke$xHealth aspects$zUnited States 606 $aAdvertising$xCigarettes$xGovernment policy$zUnited States 606 $aTobacco industry$xLaw and legislation$zUnited States 606 $aSmoking$xLaw and legislation$zUnited States 615 0$aTobacco industry$xGovernment policy 615 0$aCigarette industry 615 0$aCigarette smoke$xHealth aspects 615 0$aAdvertising$xCigarettes$xGovernment policy 615 0$aTobacco industry$xLaw and legislation 615 0$aSmoking$xLaw and legislation 676 $a362.29/65 700 $aViscusi$b W. Kip$089612 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910970630703321 996 $aSmoke-filled rooms$94365325 997 $aUNINA LEADER 05560nam 22006135 450 001 9910253944403321 005 20200705134458.0 010 $a981-10-6038-X 024 7 $a10.1007/978-981-10-6038-0 035 $a(CKB)4100000001382035 035 $a(DE-He213)978-981-10-6038-0 035 $a(MiAaPQ)EBC5185121 035 $a(PPN)222225815 035 $a(EXLCZ)994100000001382035 100 $a20171207d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiological Small Angle Scattering: Techniques, Strategies and Tips /$fedited by Barnali Chaudhuri, Inés G. Muñoz, Shuo Qian, Volker S. Urban 205 $a1st ed. 2017. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2017. 215 $a1 online resource (X, 268 p. 87 illus., 77 illus. in color.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1009 311 $a981-10-6037-1 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aSample and Buffer preparation for SAXS -- Considerations for sample preparation using size-exclusion chromatography -- How to analyze and present SAS data for publication -- Designing and Performing Biological Solution Small-Angle Neutron Scattering Contrast Variation Experiments on Multi-component Assemblies -- SAS-based structural modeling and model validation -- Structural Characterization of Highly Flexible Proteins by Small-Angle Scattering -- What can we learn from wide-angle solution scattering? -- SAS-based studies of protein fibrillation -- High Resolution Distance Distributions Determined by X-ray and Neutron Scattering -- A successful combination: coupling SE-HPLC with SAXS -- Applications of SANS to study membrane protein systems -- Hybrid applications of solution scattering to aid structural biology -- A practical guide to iSPOT modeling: An integrative structural biology platform -- Small angle scattering for pharmaceutical applications: From drugs to drug delivery system. 330 $aThis book provides a clear, comprehensible and up-to-date description of how Small Angle Scattering (SAS) can help structural biology researchers. SAS is an efficient technique that offers structural information on how biological macromolecules behave in solution. SAS provides distinct and complementary data for integrative structural biology approaches in combination with other widely used probes, such as X-ray crystallography, Nuclear magnetic resonance, Mass spectrometry and Cryo-electron Microscopy. The development of brilliant synchrotron small-angle X-ray scattering (SAXS) beam lines has increased the number of researchers interested in solution scattering. SAS is especially useful for studying conformational changes in proteins, highly flexible proteins, and intrinsically disordered proteins. Small-angle neutron scattering (SANS) with neutron contrast variation is ideally suited for studying multi-component assemblies as well as membrane proteins that are stabilized in surfactant micelles or vesicles. SAS is also used for studying dynamic processes of protein fibrillation in amyloid diseases, and pharmaceutical drug delivery. The combination with size-exclusion chromatography further increases the range of SAS applications. The book is written by leading experts in solution SAS methodologies. The principles and theoretical background of various SAS techniques are included, along with practical aspects that range from sample preparation to data presentation for publication. Topics covered include techniques for improving data quality and analysis, as well as different scientific applications of SAS. With abundant illustrations and practical tips, we hope the clear explanations of the principles and the reviews on the latest progresses will serve as a guide through all aspects of biological solution SAS. The scope of this book is particularly relevant for structural biology researchers who are new to SAS. Advanced users of the technique will find it helpful for exploring the diversity of solution SAS methods and applications. Chapter 3 of this book is available open access under a CC BY 4.0 license at link.springer.com. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1009 606 $aProteins 606 $aMolecular biology 606 $aBiotechnology 606 $aProtein Structure$3https://scigraph.springernature.com/ontologies/product-market-codes/L14050 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 606 $aBiotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12002 615 0$aProteins. 615 0$aMolecular biology. 615 0$aBiotechnology. 615 14$aProtein Structure. 615 24$aMolecular Medicine. 615 24$aBiotechnology. 676 $a537.5352 702 $aChaudhuri$b Barnali$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMuñoz$b Inés G$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aQian$b Shuo$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aUrban$b Volker S$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253944403321 996 $aBiological Small Angle Scattering: Techniques, Strategies and Tips$92264739 997 $aUNINA