LEADER 02996nam 2200577Ia 450 001 9910778711903321 005 20231009231128.0 010 $a1-280-22163-1 010 $a9786610221639 010 $a0-309-55513-2 010 $a0-585-14460-5 035 $a(CKB)111004366657404 035 $a(OCoLC)427404809 035 $a(CaPaEBR)ebrary10062946 035 $a(SSID)ssj0000127240 035 $a(PQKBManifestationID)11139730 035 $a(PQKBTitleCode)TC0000127240 035 $a(PQKBWorkID)10051710 035 $a(PQKB)10480426 035 $a(MiAaPQ)EBC3377011 035 $a(Au-PeEL)EBL3377011 035 $a(CaPaEBR)ebr10062946 035 $a(OCoLC)923267638 035 $a(EXLCZ)99111004366657404 100 $a19870928d1988 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aComplex mixtures $emethods for in vivo toxicity testing /$fCommittee on Methods for the In Vivo Toxicity Testing of Complex Mixtures, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council 210 1$aWashington, D.C. :$cNational Academy Press,$d1988. 215 $a1 online resource (xi, 227 pages) $cillustrations 300 $aBibliographic Level Mode of Issuance: Monograph 311 0 $a0-309-03778-6 320 $aIncludes bibliographies and index. 327 $a1 Front Matter; 2 Executive Summary; 3 1. Introduction; 4 2. Concepts for Analyzing Human Exposure to Complex Chemical Mixtures; 5 3. Testing Strategies and Methods; 6 4. Sampling and Chemical Characterization; 7 5. Interpretation and Modeling of Toxicity-Test Results; 8 Appendix A: Origins of Complex Mixtures; 9 Appendix B: Case Studies Establishing Active Agents and/or Interactions in Complex Mixtures; 10 Appendix C: Case Studies on Strategies for Testing the Toxicity of Complex Mixtures; 11 Appendix D: Predicting the Joint Risk of a Misture in Terms of the Component Risks; 12 Appendix E: Cancer Models; 13 Appendix F: Developmental Toxicology; 14 Appendix G: Empirical Modeling of the Toxicity of Mixtures; 15 Index 330 $aAddresses the problem of identifying and classifying complex mixtures, investigating the effect of exposure, and the research problems inherent in testing their toxicity to human beings. A series of case studies is presented, including one that examines the cofactors of alcohol consumption and cigarette smoke. 606 $aToxicity testing$xEvaluation 606 $aToxicology, Experimental 615 0$aToxicity testing$xEvaluation. 615 0$aToxicology, Experimental. 676 $a615.9/07 712 02$aNational Research Council (U.S.).$bCommittee on Methods for the In Vivo Toxicity Testing of Complex Mixtures. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910778711903321 996 $aComplex mixtures$93731914 997 $aUNINA LEADER 01915nas 2200589-a 450 001 996597371603316 005 20240413015046.0 011 $a2822-3985 035 $a(CKB)2560000000076110 035 $a(CONSER)---93954508- 035 $a(DE-599)ZDB3118792-4 035 $a(EXLCZ)992560000000076110 100 $a19911127a19889999 --- - 101 0 $atur 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aHöyük /$fTürk Tarih Kurumu 210 $aAnkara $cTürk Tarih Kurumu$d1988- 215 $a1 online resource 300 $aTitle from cover. 311 $aPrint version: Höyük / (DLC) 93954508 (OCoLC)28610544 1309-8780 606 $aExcavations (Archaeology)$zTurkey$vPeriodicals 606 $aTurkish antiquities$vPeriodicals 606 $aAntiquités turques$vPériodiques 606 $aAntiquities$2fast$3(OCoLC)fst00810745 606 $aExcavations (Archaeology)$2fast$3(OCoLC)fst00917564 606 $aTurkish antiquities$2fast$3(OCoLC)fst01159399 606 $aTúmuls$2thub 606 $aExcavacions arqueològiques$2thub 607 $aTurkey$xAntiquities$vPeriodicals 607 $aTurkey$xAntiquities$xPeriodicals 607 $aTurquie$xAntiquités$xPériodiques 607 $aTurquie$xAntiquités$vPériodiques 607 $aTurkey$2fast 607 $aTurquia$2thub 608 $aPeriodicals.$2fast 608 $aRevistes electròniques.$2thub 615 0$aExcavations (Archaeology) 615 0$aTurkish antiquities 615 6$aAntiquités turques 615 7$aAntiquities. 615 7$aExcavations (Archaeology) 615 7$aTurkish antiquities. 615 7$aTúmuls. 615 7$aExcavacions arqueològiques. 712 02$aTürk Tarih Kurumu. 906 $aJOURNAL 912 $a996597371603316 920 $aexl_impl conversion 996 $aHöyük$94160607 997 $aUNISA