LEADER 00877nlm 2200289 a 450 001 996472166403316 005 20220531142454.0 100 $a19880718d1985---- uy 0 101 0 $aeng 102 $aUS 135 $adrcnu 200 1 $aFutures past$eon the semantics of historical time$fReinhart Koselleck$gtranslated by Keith Tribe 210 1 $aCambridge, Mass$cMIT Press$d1985 215 $aTesto elettronico (PDF) (XXVI, 330 p.) 225 2 $aStudies in contemporary German social thought 230 $aBase dati testuale 410 0$aACLS Humanities E-Book. 606 0 $aFilosofia della storia$2BNCF 676 $a901 700 1$aKOSELLECK,$bReinhart$0126804 712 02$aAmerican Council of Learned Societies. 801 0$aIT$bcba$cREICAT 912 $a996472166403316 959 $aEB 969 $aER 996 $aFutures past$92855698 997 $aUNISA LEADER 05493nam 2200685 450 001 9910790902003321 005 20240102112643.0 010 $a0-19-939579-9 035 $a(CKB)2550000001302374 035 $a(EBL)1692209 035 $a(SSID)ssj0001194622 035 $a(PQKBManifestationID)12417546 035 $a(PQKBTitleCode)TC0001194622 035 $a(PQKBWorkID)11154073 035 $a(PQKB)11635318 035 $a(MiAaPQ)EBC1692209 035 $a(Au-PeEL)EBL1692209 035 $a(CaPaEBR)ebr10871675 035 $a(CaONFJC)MIL611015 035 $a(OCoLC)880147857 035 $a(EXLCZ)992550000001302374 100 $a20140526h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aStraightforward statistics $eunderstanding the tools of research /$fGlenn Geher and Sara Hall 210 1$aOxford :$cOxford University Press,$d[2014] 210 4$dİ2014 215 $a1 online resource (481 pages) 300 $aDescription based upon print version of record. 311 $a0-19-975176-5 311 $a1-306-79764-0 320 $aIncludes bibliographical references and index. 327 $aCover; Straightforward Statistics; Copyright; Contents; Preface; Acknowledgements; chapter 1 Prelude: Why Do I Need to Learn Statistics?; The Nature of Findings and Factsin the Behavioral Sciences; Statistical Significance and Effect Size; Descriptive and Inferential Statistics; A Conceptual Approach to Teachingand Learning Statistics; The Nature of this Book; How to Approach this Class andWhat You Should Get Out of It; Key Terms; chapter 2 Describing a Single Variable; Variables, Values, and Scores; Types of Variables; Describing Scores for a Single Variable; Indices of Central Tendency 327 $aIndices of Variability (and the SheerBeauty of Standard Deviation!)Rounding; Describing Frequencies of Valuesfor a Single Variable; Representing Frequency Data Graphically; Describing Data for a Categorical Variable; A Real Research Example; Summary; Key Terms; chapter 3 Standardized Scores; When a Z-Score Equals 0, the Raw ScoreIt Corresponds to Must Equal the Mean; Verbal Scores for the MadupistanAptitude Measure; Quantitative Scores for theMadupistan Aptitude Measure; Every Raw Score for Any VariableCorresponds to a Particular Z-Score 327 $aComputing Z-Scores for All Studentsfor the Madupistan Verbal TestComputing Raw Scores from Z-Scores; Comparing Your GPA of 3.10 from SolidState University with Pat's GPA of 1.95from Advanced Technical University; Each Z-Score for Any VariableCorresponds to a Particular Raw Score; Converting Z-Scores to Raw Scores(The Dorm Resident Example); A Real Research Example; Summary; Key Terms; chapter 4 Correlation; Correlations Are Summaries; Representing a Correlation Graphically; Representing a Correlation Mathematically; Return to Madupistan; Correlation Does Not Imply Causation 327 $aA Real Research ExampleSummary; Key Terms; chapter 5 Statistical Prediction and Regression; Standardized Regression; Predicting Scores on Y with DifferentAmounts of Information; Beta Weight; Unstandardized Regression Equation; The Regression Line; Quantitatively Estimating the PredictivePower of Your Regression Model; Interpreting r2; A Real Research Example; Conclusion; Key Terms; chapter 6 The Basic Elements of Hypothesis Testing; The Basic Elements ofInferential Statistics; The Normal Distribution; A Real Research Example; Summary; Key Terms; chapter 7 Introduction to Hypothesis Testing 327 $aThe Basic Rationale of Hypothesis TestingUnderstanding the BroaderPopulation of Interest; Population versus Sample Parameters; The Five Basic Steps of Hypothesis Testing; A Real Research Example; Summary; Key Terms; chapter 8 Hypothesis Testing if N > 1; The Distribution of Means; Steps in Hypothesis Testing if N > 1; Confidence Intervals; Real Research Example; Summary; Key Terms; chapter 9 Statistical Power; What Is Statistical Power?; An Example of Statistical Power; Factors that Affect Statistical Power; A Real Research Example; Summary; Key Terms 327 $achapter 10 t-tests (One-Sample and Within-Groups) 330 $aStraightforward Statistics: Understanding the Tools of Research is a clear and direct introduction to statistics for the social, behavioral, and life sciences. Based on the author's extensive experience teaching undergraduate statistics, this book provides a narrative presentation of the core principles that provide the foundation for modern-day statistics. With step-by-step guidance on the nuts and bolts of computing these statistics, the book includes detailed tutorials how to use state-of-the-art software, SPSS, to compute the basic statistics employed in modern academic and applied researc 606 $aPsychometrics 606 $aPsychology$xResearch 606 $aPsychology$xMathematical models 606 $aStatistics$xStudy and teaching (Higher) 615 0$aPsychometrics. 615 0$aPsychology$xResearch. 615 0$aPsychology$xMathematical models. 615 0$aStatistics$xStudy and teaching (Higher) 676 $a150.15195 700 $aGeher$b Glenn$01487467 702 $aHall$b Sara$f1979- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910790902003321 996 $aStraightforward statistics$93790571 997 $aUNINA LEADER 05480nam 2200721Ia 450 001 9911019442203321 005 20200520144314.0 010 $a9786610854202 010 $a9781280854200 010 $a1280854200 010 $a9783527607549 010 $a3527607544 010 $a9783527607129 010 $a3527607129 035 $a(CKB)1000000000376400 035 $a(EBL)481674 035 $a(SSID)ssj0000175535 035 $a(PQKBManifestationID)11156097 035 $a(PQKBTitleCode)TC0000175535 035 $a(PQKBWorkID)10204132 035 $a(PQKB)11608884 035 $a(MiAaPQ)EBC481674 035 $a(OCoLC)85821165 035 $a(Perlego)2769522 035 $a(EXLCZ)991000000000376400 100 $a20050519d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHydrolases in organic synthesis $eregio- and stereoselective biotransformations /$fUwe T. Bornscheuer and Romas J. Kazlauskas 205 $a2nd ed. 210 $aWeinheim $cWiley-VCH ;$aChichester $cJohn Wiley$dc2006 215 $a1 online resource (369 p.) 300 $aDescription based upon print version of record. 311 08$a9783527310296 311 08$a3527310290 320 $aIncludes bibliographical references and index. 327 $aHydrolases in Organic Synthesis; Preface for the 2(nd) edition; Preface for the 1(st) edition; Acknowledgments; Contents; 1 Introduction; 2 Designing Enantioselective Reactions; 2.1 Kinetic Resolutions; 2.1.1 Recycling and Sequential Kinetic Resolutions; 2.1.2 Dynamic Kinetic Resolutions; 2.1.2.1 Introduction; 2.1.2.2 Racemization by Protonation/Deprotonation; 2.1.2.3 Racemization by Addition/Elimination; 2.1.2.4 Racemization by Nucleophilic Substitution; 2.1.2.5 Racemization by Oxidation/Reduction; 2.1.2.6 Related Strategies; 2.2 Asymmetric Syntheses 327 $a3 Choosing Reaction Media: Water and Organic Solvents3.1 Hydrolysis in Water; 3.2 Transesterifications and Condensations in Organic Solvents; 3.2.1 Increasing the Catalytic Activity in Organic Solvents; 3.2.1.1 Choosing the Best Organic Solvent for High Activity; 3.2.2 Increasing the Enantioselectivity in Organic Solvents; 3.2.3 Water Content and Water Activity; 3.3 Other Reaction Media; 3.3.1 Ionic Liquids; 3.3.2 Reverse Micelles; 3.3.3 Supercritical Fluids; 3.4 Immobilization; 3.4.1 Introduction; 3.4.1.1 Increasing the Surface Area to Increase Catalytic Activity 327 $a4 Protein Sources and Optimization of Biocatalyst Performance4.1 Accessing Biodiversity; 4.2 Creating Improved Biocatalysts; 4.2.1 Directed Evolution; 4.2.1.1 Methods to Create Mutant Libraries; 4.2.1.2 Assay Systems; 4.2.1.3 Selected Examples; 4.2.2 Focused Directed Evolution; 4.3 Catalytic Promiscuity in Hydrolases; 4.3.1 Reactions Involving Functional Group Analogs; 4.3.1.1 Perhydrolases; 4.3.2 Aldol and Michael additions Catalyzed by Hydrolases; 4.3.2.1 Aldol Additions; 4.3.2.2 Michael-Type Additions; 4.3.3 Modifications to Introduce New Reactivity in Hydrolases 327 $a4.3.3.1 Enantioselective Reduction of Hydroperoxides with Selenosubtilisin4.3.3.2 Vanadate-Modified Phosphatases as Peroxidases; 5 Lipases and Esterases; 5.1 Availability, Structures and Properties; 5.1.1 Lipases; 5.1.1.1 Classification of Lipases; 5.1.1.2 General Features of PPL, PCL, CRL, CAL-B, and RML; 5.1.2 Esterases; 5.1.3 Lipases and Esterases are ?/? Hydrolases; 5.1.4 Lid or Flap in Interfacial Activation of Lipases; 5.1.5 Substrate Binding Site in Lipases and Esterases; 5.1.6 Designing Reactions with Lipases and Esterases; 5.1.6.1 Acyl Donor for Acylation Reactions 327 $a5.1.7 Assays for Lipases and Esterases5.1.7.1 Requirements for a Suitable Assay; 5.1.7.2 How to Distinguish Between Lipase, Esterase, and Protease; 5.2 Survey of Enantioselective Lipase-Catalyzed Reactions; 5.2.1 Alcohols; 5.2.1.1 Secondary Alcohols; 5.2.1.2 Primary Alcohols; 5.2.1.3 Other Alcohols, Amines, and Alcohol Analogs; 5.2.2 Carboxylic Acids; 5.2.2.1 General Considerations; 5.2.2.2 Carboxylic Acids with a Stereocenter at the ?-Position; 5.2.2.3 Carboxylic Acids with a Stereocenter at the ?-Position; 5.2.2.4 Other Carboxylic Acids; 5.2.2.5 Double Enantioselection; 5.2.2.6 Anhydrides 327 $a5.2.3 Lactones 330 $aFrom reviews to the first edtion:""Bornscheuer and Kazlauskas have set out, and succeeded, in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and proteases) for organic chemists. This is quite simply the best book of its type and can be unreservedly recommended to organic chemists who have an interest in using hydrolytic enzymes in synthesis."" (Nicholas J. Turner, University of Edinburgh)""The book is an indispensable source of information on the use of hydrolases in organic synthesis. The subject matter is very well set out, and the chapter 606 $aCatalysis 606 $aHydrolases 606 $aOrganic compounds$xSynthesis 615 0$aCatalysis. 615 0$aHydrolases. 615 0$aOrganic compounds$xSynthesis. 676 $a547.2 686 $a35.74$2bcl 700 $aBornscheuer$b U. T$g(Uwe Theo),$f1964-$01839804 701 $aKazlauskas$b R. J$g(Romas J.),$f1956-$0886693 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019442203321 996 $aHydrolases in organic synthesis$94419173 997 $aUNINA