LEADER 04219nam 2200589 450 001 996466700003316 005 20210213182632.0 010 $a3-540-78765-8 024 7 $a10.1007/978-3-540-78765-5 035 $a(CKB)1000000000546397 035 $a(SSID)ssj0000316372 035 $a(PQKBManifestationID)11285842 035 $a(PQKBTitleCode)TC0000316372 035 $a(PQKBWorkID)10263921 035 $a(PQKB)10394466 035 $a(DE-He213)978-3-540-78765-5 035 $a(MiAaPQ)EBC3063737 035 $a(MiAaPQ)EBC6350823 035 $a(PPN)132861380 035 $a(EXLCZ)991000000000546397 100 $a20210213d2008 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 00$aAspects of physical biology $ebiological water, protein solutions, transport and replication /$fG. Franzese, M. Rubi, editors 205 $a1st ed. 2008. 210 1$aBerlin :$cSpringer,$d[2008] 210 4$dİ2008 215 $a1 online resource (IX, 233 p.) 225 1 $aLecture Notes in Physics,$x0075-8450 ;$v752 300 $aContributions from a conference held in Sitges (Barcelona) Spain on 5-9 June, 2006. 311 $a3-540-78764-X 320 $aIncludes bibliographical references and index. 327 $aBiological Water -- Dynamics of Water at Low Temperatures and Implications for Biomolecules -- Anomalous Behaviour of Supercooled Water and Its Implication for Protein Dynamics -- Interactions of Polarizable Media inWater and the Hydrophobic Interaction -- Protein and Biological Solutions -- Metastable Mesoscopic Phases in Concentrated Protein Solutions -- Application of Discrete Molecular Dynamics to Protein Folding and Aggregation -- Cooperative Effects in Biological Suspensions: From Filaments to Propellers -- Transport and Replication -- A Thermodynamic Description of Active Transport -- Energy Interconversion in Transport ATPases Role of Water in Ions Transport and in the Energy of Hydrolysis of Phosphate Compounds -- A Novel Mechanism for Activator-Controlled Initiation of DNA Replication that Resolves the Auto-regulation Sequestration Paradox -- Activity-Dependent Model for Neuronal Avalanches. 330 $aThe application to Biology of the methodologies developed in Physics is attracting an increasing interest from the scientific community. It has led to the emergence of a new interdisciplinary field, called Physical Biology, with the aim of reaching a better understanding of the biological mechanisms at molecular and cellular levels. Statistical Mechanics in particular plays an important role in the development of this new field. For this reason, the XXth session of the famous Sitges Conference on Statistical Physics was dedicated to "Physical Biology: from Molecular Interactions to Cellular Behavior". As is by now tradition, a number of lectures were subsequently selected, expanded and updated for publication as lecture notes, so as to provide both a state-of-the-art introduction and overview to a number of subjects of broader interest and to favor the interchange and cross-fertilization of ideas between biologists and physicists. The present volume focuses on three main subtopics (biological water, protein solutions as well as transport and replication), presenting for each of the them the on-going debates on recent results. The role of water in biological processes, the mechanisms of protein folding, the phases and cooperative effects in biological solutions, the thermodynamic description of replication, transport and neural activity, all are subjects that are revised in this volume, based on new experiments and new theoretical interpretations. 410 0$aLecture Notes in Physics,$x0075-8450 ;$v752 606 $aBiophysics$xTechnique 606 $aStatistical physics$xData processing 615 0$aBiophysics$xTechnique. 615 0$aStatistical physics$xData processing. 676 $a574.191 702 $aFranzese$b Giancarlo 702 $aRubi$b M. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996466700003316 996 $aAspects of Physical Biology$9774428 997 $aUNISA