LEADER 00856nam0-22003131i-450- 001 990001017020403321 010 $a0-471-49190-X 035 $a000101702 035 $aFED01000101702 035 $a(Aleph)000101702FED01 035 $a000101702 100 $a20000920d1972----km-y0itay50------ba 101 0 $aeng 200 1 $aTrends in General System Theory$fEdited by George J. Klir 210 $aNew York$cWiley-Interscience$d1972 610 0 $aCibernetica 610 0 $aTeoria dei giochi 610 0 $aTeoria degli automi 610 0 $aIntelligenza artificiale 676 $a510.78 700 1$aKlir,$bGeorge J.$027781 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990001017020403321 952 $a8-127$b9628$fFI1 959 $aFI1 996 $aTrends in General System Theory$9355344 997 $aUNINA DB $aING01 LEADER 02604nam 2200625 450 001 996466667203316 005 20220908144451.0 010 $a3-540-36621-0 024 7 $a10.1007/BFb0067737 035 $a(CKB)1000000000438601 035 $a(SSID)ssj0000323845 035 $a(PQKBManifestationID)12117811 035 $a(PQKBTitleCode)TC0000323845 035 $a(PQKBWorkID)10303422 035 $a(PQKB)10136701 035 $a(DE-He213)978-3-540-36621-8 035 $a(MiAaPQ)EBC5585810 035 $a(Au-PeEL)EBL5585810 035 $a(OCoLC)1066177849 035 $a(MiAaPQ)EBC6842247 035 $a(Au-PeEL)EBL6842247 035 $a(OCoLC)1293255884 035 $a(PPN)155204106 035 $a(EXLCZ)991000000000438601 100 $a20220908d1971 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 00$aH-spaces $eactes de la re?union de Neucha?tel (Suisse) aou?t 1970. /$fedited by Franc?ois Sigrist 205 $a1st ed. 1971. 210 1$aBerlin, Germany ;$aNew York, New York :$cSpringer-Verlag,$d[1971] 210 4$dİ1971 215 $a1 online resource (V, 156 p.) 225 1 $aLecture Notes in Mathematics,$x0075-8434 ;$v196 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-540-05461-8 327 $aFamilies of finite H-complexes ? Revisited -- H-spaces Mod p (I) -- H-spaces Mod p (II) -- Mod p decomposition of lie groups -- On spherical classes in the cohomology of H-spaces -- On the homotopy classification of rank 3-H-spaces -- H-maps between spheres -- On H-spaces of finite dimension -- Infinite loop spaces ? An historical survey -- Classifying spaces for homotopy-everything H-spaces -- The universal H-space of a monoid -- Categorical constructions in algebraic topology -- On a type of differential Hopf algebras -- Polynomial algebras over the algebra of cohomology operations -- On quasi-fibrations and orthogonal bundles -- Some remarks on vector fields -- A finite complex whose rational homotopy is not finitely generated -- H-space problems -- Bibliography on H-spaces. 410 0$aLecture Notes in Mathematics,$x0075-8434 ;$v196 606 $aH-spaces 606 $aHopf algebras 606 $aMathematics 615 0$aH-spaces. 615 0$aHopf algebras. 615 0$aMathematics. 676 $a514.224 702 $aSigrist$b Franc?ois 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996466667203316 996 $aH-spaces$980378 997 $aUNISA LEADER 06008nam 22007095 450 001 9910300300803321 005 20200705021958.0 010 $a3-319-78538-9 024 7 $a10.1007/978-3-319-78538-7 035 $a(CKB)4100000007127479 035 $a(MiAaPQ)EBC5596953 035 $a(DE-He213)978-3-319-78538-7 035 $a(PPN)232471487 035 $a(EXLCZ)994100000007127479 100 $a20181110d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAntimicrobial Resistance in the 21st Century /$fedited by I. W. Fong, David Shlaes, Karl Drlica 205 $a2nd ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (773 pages) 225 1 $aEmerging Infectious Diseases of the 21st Century 311 $a3-319-78537-0 320 $aIncludes bibliographical references and index. 327 $aChapter1: Introduction : Coordinated Global Action is Needed to Combat Antimicrobial Resistance -- Part I: Examples of Resistance -- Chapter2: Antimicrobial Resistance Among Streptococcus pneumoniae -- Chapter3: Emergence of MRSA in the Community -- Chapter4: Resistance of Gram-negative Bacilli to Antimicrobials -- Chapter5: Drug Resistance in Tuberculosis -- Chapter6: Anaerobic Bacteria: Antimicrobial Susceptibility Testing and Resistance Patterns -- Chapter7: Clinical Significance and Biologic Basis of HIV Drug Resistance -- Chapter8: Resistance of Herpesviruses to Antiviral Agents -- Chapter9: Heteroresistance: A Harbinger of Future Resistance -- Part II: Biology of Resistance -- Chapter10: Epidemiology of Bacterial Resistance -- Chapter11: Transmissible Antibiotic Resistance -- Chapter12: Antibiotics and Resistance in the Environment -- Chapter13: Phenotypic Tolerance and Bacterial Persistence -- Chapter14: Staphylococcus aureus Adaptation During Infection -- Chapter15: Bacterial Signal Transduction Systems in Antimicrobial Resistance -- Chapter16: Fluoroquinolone Interactions with Bacterial Type II Topoisomerases and Target-mediated Drug Resistance -- Part III: Finding New Antimicrobials -- Chapter17: Natural Products in Antibiotic Discovery -- Chapter18: The New vs. Old Target Debate For Drug Discovery -- Chapter19: Non-quinolone Topoisomerase Inhibitors -- Chapter20: Antimicrobial-Mediated Bacterial Suicide -- Chapter21: PK/PD-based Prediction of ?Anti-mutant? Antibiotic Exposures Using In Vitro Dynamic Models -- Part IV: Bringing Compounds to Market -- Chapter22: The Role of Pharmacometrics in the Development of Antimicrobial Agents -- Chapter23: New Regulatory Pathways for Antibacterial Drugs -- Chapter24: Economic Incentives for Antibacterial Drug Development: Alternative Market Structures to Promote Innovation. 330 $a Antimicrobial resistance is now a general problem. Many of us have elderly relatives who died from a drug-resistant infection, and some of us have suffered from a resistant urinary infection that likely came from intestinal bacteria following antibiotic consumption. Antimicrobial Resistance in the 21st Century provides a broad introduction to the subject in which the situation with problematic pathogens is detailed, the biology of resistance is described, and gaining approval for new antibiotics is discussed. Some topics are immediately practical, such as watching for resistant pathogen sub-populations in cultures taken from patients; other topics point to future research efforts that may lead to new antimicrobials and ways to stimulate the action of existing ones. Overall, Antimicrobial Resistance in the 21st Century provides an update for physicians, serves as a starting point for graduate students interested in solving the resistance problem, and may serve as a text for a course on resistance. Lay readers familiar with microbiology will gain an appreciation for a medical issue that promises to be one of the most important of our time. Ignatius Fong, Department of Medicine, University of Toronto Series Editor ? Emerging Infectious Diseases of the 21st Century David Shlaes, Founder, Anti-Infectives Consulting Editor ? 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