LEADER 06515nam 22007455 450 001 996466258303316 005 20200701054922.0 010 $a3-642-02008-9 024 7 $a10.1007/978-3-642-02008-7 035 $a(CKB)1000000000746059 035 $a(SSID)ssj0000319831 035 $a(PQKBManifestationID)11252079 035 $a(PQKBTitleCode)TC0000319831 035 $a(PQKBWorkID)10338836 035 $a(PQKB)11359673 035 $a(DE-He213)978-3-642-02008-7 035 $a(MiAaPQ)EBC3064194 035 $a(PPN)136301231 035 $a(EXLCZ)991000000000746059 100 $a20100301d2009 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aResearch in Computational Molecular Biology$b[electronic resource] $e13th Annual International Conference, RECOMB 2009, Tucson, Arizona, USA, May 18-21, 2009, Proceedings /$fedited by Serafim Batzoglou 205 $a1st ed. 2009. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2009. 215 $a1 online resource (XVI, 534 p.) 225 1 $aLecture Notes in Bioinformatics ;$v5541 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-642-02007-0 327 $aSearching Protein 3-D Structures in Linear Time -- Optimization-Based Peptide Mass Fingerprinting for Protein Mixture Identification -- Boosting Protein Threading Accuracy -- New Perspectives on Gene Family Evolution: Losses in Reconciliation and a Link with Supertrees -- A Probabilistic Graphical Model for Ab Initio Folding -- Topology-Free Querying of Protein Interaction Networks -- Cross Species Expression Analysis of Innate Immune Response -- Haplotype Inference in Complex Pedigrees -- Storage and Retrieval of Individual Genomes -- An Online Approach for Mining Collective Behaviors from Molecular Dynamics Simulations -- Parameter Synthesis in Nonlinear Dynamical Systems: Application to Systems Biology -- Spatial Clustering of Multivariate Genomic and Epigenomic Information -- How Many Bootstrap Replicates Are Necessary? -- A Robust Bayesian Two-Sample Test for Detecting Intervals of Differential Gene Expression in Microarray Time Series -- Incorporating Nucleosomes into Thermodynamic Models of Transcription Regulation -- Combinatorial Algorithms for Structural Variation Detection in High Throughput Sequenced Genomes -- Optimizing PCR Assays for DNA Based Cancer Diagnostics -- The Multi-State Perfect Phylogeny Problem with Missing and Removable Data: Solutions via Integer-Programming and Chordal Graph Theory -- COE: A General Approach for Efficient Genome-Wide Two-Locus Epistasis Test in Disease Association Study -- Overlapping Pools for High Throughput Targeted Resequencing -- Deep Sequencing of a Genetically Heterogeneous Sample: Local Haplotype Reconstruction and Read Error Correction -- Lifting Prediction to Alignment of RNA Pseudoknots -- Detection of Locally Over-Represented GO Terms in Protein-Protein Interaction Networks -- Protein Fragment Swapping: A Method for Asymmetric, Selective Site-Directed Recombination -- Simultaneous Alignment and Folding of Protein Sequences -- Shared Peptides in Mass Spectrometry Based Protein Quantification -- Evaluating Between-Pathway Models with Expression Data -- Sorting Signed Permutations by Inversions in O(nlogn) Time -- Finding Biologically Accurate Clusterings in Hierarchical Tree Decompositions Using the Variation of Information -- Identification and Frequency Estimation of Inversion Polymorphisms from Haplotype Data -- On the Relationship between DNA Periodicity and Local Chromatin Structure -- Phylogenies without Branch Bounds: Contracting the Short, Pruning the Deep -- Detecting the Presence and Absence of Causal Relationships between Expression of Yeast Genes with Very Few Samples -- An Adaptive and Memory Efficient Algorithm for Genotype Imputation -- A Statistical Framework for the Functional Analysis of Metagenomes -- Learning Models for Aligning Protein Sequences with Predicted Secondary Structure. 330 $aThis book constitutes the refereed proceedings of the 13th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2009, held in Tucson, Arisona, USA in May 2009. The 37 revised full papers presented were carefully reviewed and selected from 166 submissions. As the top conference in computational molecular biology, RECOMB addresses all current issues in algorithmic, theoretical, and experimental bioinformatics such as molecular sequence analysis, recognition of genes and regulatory elements, molecular evolution, protein structure, structural genomics, gene expression, gene networks, drug design, combinatorial libraries, computational proteomics, as well as structural and functional genomics. 410 0$aLecture Notes in Bioinformatics ;$v5541 606 $aLife sciences 606 $aComputer programming 606 $aArtificial intelligence 606 $aBioinformatics 606 $aAlgorithms 606 $aDatabase management 606 $aLife Sciences, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L00004 606 $aProgramming Techniques$3https://scigraph.springernature.com/ontologies/product-market-codes/I14010 606 $aArtificial Intelligence$3https://scigraph.springernature.com/ontologies/product-market-codes/I21000 606 $aComputational Biology/Bioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/I23050 606 $aAlgorithm Analysis and Problem Complexity$3https://scigraph.springernature.com/ontologies/product-market-codes/I16021 606 $aDatabase Management$3https://scigraph.springernature.com/ontologies/product-market-codes/I18024 615 0$aLife sciences. 615 0$aComputer programming. 615 0$aArtificial intelligence. 615 0$aBioinformatics. 615 0$aAlgorithms. 615 0$aDatabase management. 615 14$aLife Sciences, general. 615 24$aProgramming Techniques. 615 24$aArtificial Intelligence. 615 24$aComputational Biology/Bioinformatics. 615 24$aAlgorithm Analysis and Problem Complexity. 615 24$aDatabase Management. 676 $a570 702 $aBatzoglou$b Serafim$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a996466258303316 996 $aResearch in Computational Molecular Biology$9772065 997 $aUNISA