LEADER 05154nam 2200613 450 001 996426337703316 005 20201221190235.0 010 $a0-12-417115-X 035 $a(CKB)3710000000085686 035 $a(EBL)1632055 035 $a(OCoLC)870949356 035 $a(SSID)ssj0001161614 035 $a(PQKBManifestationID)11651155 035 $a(PQKBTitleCode)TC0001161614 035 $a(PQKBWorkID)11128693 035 $a(PQKB)11286612 035 $a(MiAaPQ)EBC1632055 035 $a(PPN)199262276 035 $a(EXLCZ)993710000000085686 100 $a20140306h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aKey chiral auxiliary applications /$fGregory Roos 205 $a2nd ed. 210 1$aWaltham, [Massachusetts] ;$aAmsterdam, The Netherlands :$cAcademic Press,$d2014. 210 4$dİ2014 215 $a1 online resource (1271 p.) 300 $aDescription based upon print version of record. 311 $a0-12-417034-X 320 $aIncludes bibliographical references. 327 $aFront Cover; Key Chiral Auxiliary Applications; Copyright; CONTENTS; ACKNOWLEDGEMENTS; FOREWORD; PREFACE TO THE 2ND EDITION; ABBREVIATIONS; 1.INTRODUCTION; 1.1. BACKGROUND; 1.2. THE CHIRAL AUXILIARY APPROACH; 1.3. THIS COLLECTION; REFERENCES; 2.ALKYLATION AND RELATED REACTIONS I; 2.1 ALLYL AND BENZYL RELATED CARBANIONS; 2.2 ALLENIC ETHER TANDEM ACYLATION-CYCLIZATION; 2.3 ALDEHYDE DERIVED NUCLEOPHILES; 2.4 KETONE DERIVED NUCLEOPHILES; 2.5 ALDEHYDE AND KETONE ENOLATES WITH AUXILIARY-CONTAINING ELECTROPHILES; REFERENCES; 3.ALKYLATION AND RELATED REACTIONS II 327 $a3.1 ?-ALKYLATION OF CARBOXYLIC ACID DERIVED NUCLEOPHILESREFERENCES; 4.ALKYLATION AND RELATED REACTIONS III; 4.1 ?-ALKYLATION OF -HETEROATOM SUBSTITUTED ACID DERIVATIVES; 4.2 ?-ALKYLATION OF CYCLIC CARBOXYLIC ACID DERIVATIVES; REFERENCES; 5.ALKYLATION AND RELATED REACTIONS IV; 5.3 ?-HYDROXYLATION OF ACID DERIVATIVES; 5.1 ?-ACYLATION OF ACID DERIVATIVES; 5.2 ?-AMINATION OF ACYL DERIVATIVES; 5.4 ?-SILYLATION, ?-THIOLATION, AND ?-SELENATION OF ACID DERIVATIVES; 5.5 ?-HALOGENATION OF ACID DERIVATIVES; 5.6 REACTION OF PHOSPHORIC ACID DERIVATIVES WITH ELECTROPHILES 327 $a5.7 ?-ALKYLATION OF SULFONIC ACID DERIVATIVES5.8 AROMATIC SUBSTITUTION; 5.9 NUCLEOPHILIC ALLYLIC SUBSTITUTION; 5.10 MISCELLANEOUS REACTIONS; REFERENCES; 6.ELECTROPHILIC RELATED ADDITION TO C=C; 6.1 REDUCTION AND RELATED REACTIONS; 6.2 ADDITION OF HALO-CONTAINING ADDENDS; 6.3 BISAMINATION; 6.4 ADDITION OF OXY-ADDENDS; 6.5 CYCLOPROPANATION; 6.6 CYCLOPROPENATION; 6.7 AZIRIDINATION; 6.8 ALKOXYSELENATION; 6.9 RADICAL ADDITION; REFERENCES; 7.CONJUGATE ADDITION I; 7.1 AUXILIARY ON DONOR NUCLEOPHILE - SIMPLE ADDITION; 7.2 AUXILIARY ON DONOR NUCLEOPHILE - TANDEM ADDITION; REFERENCES 327 $a8.CONJUGATE ADDITION II8.1 AUXILIARY ON ACCEPTOR ?,?-UNSATURATED SYSTEM - SIMPLE ADDITION; REFERENCES; 9.CONJUGATE ADDITION III; 9.1 ?,?-UNSATURATED ACYL DERIVATIVES - ADDITION OF HETERONUCLEOPHILES; 9.2 OTHER ACTIVATED SYSTEMS; 9.3 INTRAMOLECULAR REACTIONS; 9.4 AUXILIARY ON ?,?-UNSATURATED SYSTEM - TANDEM ADDITION OFCARBON NUCLEOPHILES; 9.5 AUXILIARY ON ACCEPTOR ?,?-UNSATURATED SYSTEM - TANDEM ADDITION OFHETERONUCLEOPHILES; 9.6 AUXILIARY ON ACCEPTOR ?,?-UNSATURATED SYSTEM - RADICAL ADDITION; 9.7 NUCLEOPHILIC ADDITION TO TRANSITION-METAL ALKENE/ARENE COMPLEXES; REFERENCES 327 $a10.ADDITION TO C=N BONDS10.1 REDUCTION OF IMINES, IMINIUM IONS, HYDRAZONES AND OXIMES; 10.2 NUCLEOPHILIC ADDITION; 10.3 RADICAL ADDITION; 10.4 UGI COUPLING; REFERENCES; 11.ADDITION TO C=O BONDS I; 11.1 REDUCTION; 11.2 WITTIG & RELATED OLEFINATION; 11.3 ADDITION OF ORGANOMETALLIC AND RELATED REAGENTS; REFERENCES; 12.ADDITION TO C=O BONDS II; 12.1 ADDITION OF ENOLATES (ALDOL AND RELATED REACTIONS); REFERENCES; 13.ADDITION TO C=O BONDS III; 13.1 ADDITION OF ENOLATES (ALDOL AND RELATED REACTIONS); 13.2 TANDEM REACTIONS; 13.3 RADICAL REACTIONS; REFERENCES; 14. CYCLOADDITIONS I 327 $a14.1 [2+2]-CYCLOADDITIONS 330 $aKey Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of resul 606 $aAsymmetric synthesis 606 $aEnantioselective catalysis 606 $aEnantiomers 608 $aElectronic books. 615 0$aAsymmetric synthesis. 615 0$aEnantioselective catalysis. 615 0$aEnantiomers. 676 $a547 700 $aRoos$b Gregory$0872485 801 0$bMiAaPQ 906 $aBOOK 912 $a996426337703316 996 $aKey chiral auxiliary applications$92371770 997 $aUNISA