LEADER 01016nlm 2200265Ia 450 001 996422744403316 005 20210702102647.0 100 $a19840121d1661---- uy | 101 0 $aeng 102 $aUK 135 $adrcnu 200 1 $a<> measuring rule concerning liberty and persecution$eand who have been the persecutors and who have been the sufferers from the beginning$ealso the stock and line from whence the persecutor has had his rise and descent, and of what stock they are that cumber Gods earth 210 1 $a[S.l.$cs.n.$d1661?] 215 $aTesto elettronico (PDF) (8 p.) 230 $aBase dati testuale 300 $aRiproduzione dell'originale nella Harvard University Library Congress. 606 0 $aQuaccheri$xTesti$xApologetica$2BNCF 676 $a289 700 1$aFOX,$bGeorge$f1624-1691.$0793686 801 0$bcba$aIT$bcba$gREICAT 912 $a996422744403316 959 $aEB 969 $aER 996 $aMeasuring rule concerning liberty and persecution$91823620 997 $aUNISA LEADER 03096nam 2200637 a 450 001 9910461619003321 005 20200520144314.0 010 $a1-283-14344-5 010 $a9786613143440 010 $a1-84816-593-5 035 $a(CKB)2670000000095737 035 $a(EBL)731089 035 $a(OCoLC)738433271 035 $a(SSID)ssj0000522091 035 $a(PQKBManifestationID)12205256 035 $a(PQKBTitleCode)TC0000522091 035 $a(PQKBWorkID)10522821 035 $a(PQKB)10196654 035 $a(MiAaPQ)EBC731089 035 $a(WSP)0000P729 035 $a(Au-PeEL)EBL731089 035 $a(CaPaEBR)ebr10480223 035 $a(CaONFJC)MIL314344 035 $a(EXLCZ)992670000000095737 100 $a20110714d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aDNA deamination and the immune system$b[electronic resource] $eAID in health and disease /$feditors, Sebastian Fugmann, Marilyn Diaz, Nina Papavasiliou 210 $aLondon $cImperial College Press$d2011 215 $a1 online resource (232 p.) 225 1 $aMolecular medicine and medicinal chemistry ;$vv. 3 300 $aDescription based upon print version of record. 311 $a1-84816-592-7 320 $aIncludes bibliographical references and index. 327 $aPreface; Contents; List of Tables; List of Figures; Chapter 1 Introduction; Chapter 2 Switch Regions, ChromatinAccessibility and AID Targeting; Chapter 3 Cis-Regulatory Elements that Target AID to Immunoglobulin Loci; Chapter 4 Partners in Diversity: The Search for AID Co-Factors; Chapter 5 Resolution of AID Lesions in Class Switch Recombination; Chapter 6 Error-Prone and Error-Free Resolution of AID Lesions in SHM; Chapter 7 Regulatory Mechanisms of AID Function; Chapter 8 AID in Immunodeficiency and Cancer; Chapter 9 AID in Aging and in Autoimmune Disease; Index 330 $aThis book covers the current understanding of the role of activation-induced cytidine deaminase (AID) in the generation of antibody response to antigenic challenge. Since the discovery of AID, and the genetic demonstration of its role in somatic hypermutation and class-switch recombination of antibody genes, much has been learned about the biochemistry of this enzyme. However, some key questions remain hotly contested, such as: how does this enzyme get to the antibody locus leaving the rest of the genome intact, and why are DNA repair pathways which normally repair deamination events co-opted 410 0$aMolecular medicine and medicinal chemistry ;$vv. 3. 606 $aDNA 606 $aImmune system 608 $aElectronic books. 615 0$aDNA. 615 0$aImmune system. 676 $a571.967 701 $aFugmann$b Sebastian$0911294 701 $aDiaz$b Marilyn$0911295 701 $aPapavasiliou$b Nina$0911296 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910461619003321 996 $aDNA deamination and the immune system$92040829 997 $aUNINA LEADER 01730nam 2200373 n 450 001 996390083703316 005 20200824120644.0 035 $a(CKB)4940000000099605 035 $a(EEBO)2248496418 035 $a(UnM)99829615e 035 $a(UnM)99829615 035 $a(EXLCZ)994940000000099605 100 $a19950615d1651 uy | 101 0 $aeng 135 $aurbn||||a|bb| 200 04$aThe historie of the pitifull life, and unfortunate death of Edward the V.th$b[electronic resource] $eand the then Duke of Yorke his brother. With the troublesome and tyrannicall government of usurping Richard the III. and his miserable end. Written by the right honourable, Sir Thomas Moore, sometimes Lord Chancellor of England 210 $aLondon $cprinted for William Sheares, at the Bible in St. Pauls Church-yard$d1651 215 $a[8], 144, 135-179, 178-179, [1], 185-422, p. 325, 426-461, [1] p., 1 leaf of plate $cill 300 $aWith an engraved frontispiece portrait of Edward the 5th. 300 $aText appears to be continuous despite pagination. 300 $aThe tragicall historie of King Richard the Third has caption title. Pagination and register are continuous. 300 $aReproduction of the original in the Bodleian Library. 330 $aeebo-0014 607 $aGreat Britain$xHistory$yHouse of York, 1461-1485 607 $aGreat Britain$xHistory$yRichard III, 1483-1485 700 $aMore$b Thomas$cSir, Saint,$f1478-1535.$0387591 801 0$bCu-RivES 801 1$bCu-RivES 801 2$bCStRLIN 801 2$bWaOLN 906 $aBOOK 912 $a996390083703316 996 $aThe historie of the pitifull life, and unfortunate death of Edward the V.th$92400433 997 $aUNISA