LEADER 07290nam 22006975 450 001 996418310203316 005 20200817103120.0 010 $a3-030-57821-6 024 7 $a10.1007/978-3-030-57821-3 035 $a(CKB)4100000011389986 035 $a(DE-He213)978-3-030-57821-3 035 $a(MiAaPQ)EBC6308647 035 $a(PPN)255477317 035 $a(EXLCZ)994100000011389986 100 $a20200817d2020 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBioinformatics Research and Applications$b[electronic resource] $e16th International Symposium, ISBRA 2020, Moscow, Russia, December 1?4, 2020, Proceedings /$fedited by Zhipeng Cai, Ion Mandoiu, Giri Narasimhan, Pavel Skums, Xuan Guo 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (XIV, 418 p. 143 illus., 110 illus. in color.) 225 1 $aLecture Notes in Bioinformatics ;$v12304 311 $a3-030-57820-8 320 $aIncludes bibliographical references and index. 327 $aMitochondrial Haplogroup Assignment for High-Throughput Sequencing Data from Single Individual and Mixed DNA Samples -- Signet Ring Cell Detection with Classi cation Reinforcement Detection Network -- SPOC: Identification of Drug Targets in Biological Networks via Set Preference Output Control -- Identification of a novel compound heterozygous variant in NBAS causing bone fragility by the type of osteogenesis imperfecta -- Isoform-disease association prediction by data fusion -- EpIntMC: Detecting Epistatic Interactions using Multiple Clusterings -- Improving Metagenomic Classi cation using discriminative k-mers from sequencing data -- Dilated-DenseNet For Macromolecule Classifi cation In Cryo-electron Tomography -- Ess-NEXG: Predict Essential Proteins by Constructing a Weighted -- Protein Interaction Network based on Node Embedding and XGBoost -- mapAlign: an efficient approach for mapping and aligning long reads to reference genomes -- Functional Evolutionary Modeling Exposes Overlooked Protein-Coding Genes Involved in Cancer -- Testing the Agreement of Trees with Internal Labels -- SVLR: Genome Structure Variant Detection Using Long Read Sequencing Data -- De novo prediction of drug-target interaction via Laplacian regularized Schatten-p norm minimization -- Diagnosis of ASD from rs-fMRIs based on brain dynamic networks -- miRNA-Disease Associations Prediction Based on Negative Sample Selection and Multi-layer Perceptron -- Checking Phylogenetic Decisiveness in Theory and in Practice -- TNet: Phylogeny-Based Inference of Disease Transmission Networks Using Within-Host Strain Diversity -- Cancer breakpoint hotspots versus individual breakpoints prediction by machine learning models -- Integer Linear Programming Formulation for the Uni ed DuplicationLoss-Coalescence Model -- In silico-guided discovery of potential HIV-1 entry inhibitors mimicking bNAb N6: virtual screening, docking, molecular dynamics, and post-molecular modeling analysis -- Learning Structural Genetic Information via Graph Neural Embedding -- A New Network-based Tool to Analyse Competing Endogenous RNAs -- Deep Ensemble models for 16S Ribosomal Gene Classification -- Search for tandem repeats in the rst chromosome from the rice genome -- Deep Learning approach with rotate-shift invariant input to predict protein homodimer structure -- Development of a Neural Network-Based Approach for Prediction of Potential HIV-1 Entry Inhibitors Using Deep Learning and Molecular Modeling Methods -- In Silico Design and Evaluation of Novel Triazole-Based Compounds as Promising Drug Candidates Against Breast Cancer -- Identification of essential genes with NemoPro le and various machine learning models -- NemoLib: Network Motif Libraries for network motif detection and analysis -- Estimating enzyme participation in metabolic pathways for microbial communities from RNA-seq data -- Identication of Virus-Receptor Interactions based on Network Enhancement and Similarity -- Enhanced functional pathway annotations for differentially expressed gene clusters -- Automated Detection of Sleep Apnea from Abdominal Respiratory Signal using Hilbert-Huang Transform -- Na/K-ATPase glutathionylation: in silico modeling of reaction mechanisms -- HiChew: a tool for TAD clustering in embryogenesis -- Generation of Hi-C maps from DNA sequence data using Deep Learning -- SC1: A Tool for Interactive Web-Based Single Cell RNA-Seq Data Analysis -- Quantitative analysis of the dynamics of maternal gradients in the early Drosophila embryo -- Atom Tracking Using Cayley Graphs -- SPOC: Identification of Drug Targets in Biological Networks via Set Preference Output Control -- Identification of a novel compound heterozygous variant in NBAS causing bone fragility by the type of osteogenesis imperfecta. . 330 $aThis book constitutes the proceedings of the 16th International Symposium on Bioinformatics Research and Applications, ISBRA 2020, held in Moscow, Russia, in December 2020. The 23 full papers and 18 short papers presented in this book were carefully reviewed and selected from 131 submissions. They were organized in topical sections named: genome analysis; systems biology; computational proteomics; machine and deep learning; and data analysis and methodology. 410 0$aLecture Notes in Bioinformatics ;$v12304 606 $aBioinformatics 606 $aComputers 606 $aArtificial intelligence 606 $aComputer organization 606 $aBioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/L15001 606 $aInformation Systems and Communication Service$3https://scigraph.springernature.com/ontologies/product-market-codes/I18008 606 $aArtificial Intelligence$3https://scigraph.springernature.com/ontologies/product-market-codes/I21000 606 $aComputer Systems Organization and Communication Networks$3https://scigraph.springernature.com/ontologies/product-market-codes/I13006 606 $aComputational Biology/Bioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/I23050 615 0$aBioinformatics. 615 0$aComputers. 615 0$aArtificial intelligence. 615 0$aComputer organization. 615 14$aBioinformatics. 615 24$aInformation Systems and Communication Service. 615 24$aArtificial Intelligence. 615 24$aComputer Systems Organization and Communication Networks. 615 24$aComputational Biology/Bioinformatics. 676 $a572.80285 702 $aCai$b Zhipeng$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMandoiu$b Ion$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aNarasimhan$b Giri$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSkums$b Pavel$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGuo$b Xuan$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996418310203316 996 $aBioinformatics Research and Applications$9772362 997 $aUNISA