LEADER 01318nam 2200325Ia 450 001 996397229203316 005 20221107143218.0 035 $a(CKB)4940000000063865 035 $a(EEBO)2264208185 035 $a(OCoLC)08801192 035 $a(EXLCZ)994940000000063865 100 $a19820923d1689 uy | 101 0 $alat 135 $aurbn||||a|bb| 200 10$aAesopi fabulae Anglo-Latinae$b[electronic resource] $equarum singulae in distinctas suas periodos, numericis characteribus annotatas, ita dividuntur ut in eisdem transcribendis & transferendis exercitati pueruli, non modo regulas quascunque grammaticas accuratius intelligant, sed & aptam verborum compositionem, atque idiomata utriusque linguae felici`us prosequantur, atq imitentur /$fa Carolo Hoole 210 $aLondini $cExcudebat M.F. pro Societate Stationariorum$d1689 215 $a[6], 263 p 300 $aAdded t.p. in English. 300 $aLatin and English on facing pages. 300 $aReproduction of original in the Cambridge University Library. 330 $aeebo-0021 700 $aAesop$0859552 701 $aHoole$b Charles$f1610-1667.$0793350 801 0$bEEU 801 1$bEEU 801 2$bWaOLN 906 $aBOOK 912 $a996397229203316 996 $aAesopi fabulae Anglo-Latinae$92365144 997 $aUNISA LEADER 03839nam 22006735 450 001 9910865241003321 005 20250220142229.0 010 $a9783031440878$b(electronic bk.) 010 $z9783031440861 024 7 $a10.1007/978-3-031-44087-8 035 $a(MiAaPQ)EBC31496597 035 $a(Au-PeEL)EBL31496597 035 $a(CKB)32317897700041 035 $a(DE-He213)978-3-031-44087-8 035 $a(EXLCZ)9932317897700041 100 $a20240617d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCongenital Heart Diseases: The Broken Heart $eClinical Features, Human Genetics and Molecular Pathways /$fedited by Silke Rickert-Sperling, Robert G. Kelly, Nikolaus Haas 205 $a2nd ed. 2024. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2024. 215 $a1 online resource (1098 pages) 225 1 $aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1441 311 08$aPrint version: Rickert-Sperling, Silke Congenital Heart Diseases: the Broken Heart Cham : Springer International Publishing AG,c2024 9783031440861 320 $aIncludes bibliographical references and index. 327 $aSection I: General introduction in cardiac development -- Section II: Different chapters covering the different types of congenital heart disease -- Section III: The overall perspective. 330 $aThis 2nd edition has been extensively updated and provides comprehensive and current insight into congenital heart diseases, from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways. The book is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and insights from animal models and pathways. All chapters have been updated and new chapters added on state-of-the-art approaches including stem cells and organoids, cardiac metabolism, single cell transcriptomics and 3D reconstruction of human heart development. The clinical chapters have been extended and include new sections on diagnostic imaging techniques. Taken together, the book, written by and for clinicians and researchers, provides an integrated and up-to-date resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease. Chapter 11 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. 410 0$aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1441 606 $aMedical genetics 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aCardiology 606 $aMedicine 606 $aMedical Genetics 606 $aBiomedical Research 606 $aCardiology 606 $aClinical Medicine 615 0$aMedical genetics. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aCardiology. 615 0$aMedicine. 615 14$aMedical Genetics. 615 24$aBiomedical Research. 615 24$aCardiology. 615 24$aClinical Medicine. 676 $a616.12043 702 $aRickert-Sperling$b Silke 702 $aKelly$b R. G. 702 $aHaas$b Nikolaus 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910865241003321 996 $aCongenital Heart Diseases: The Broken Heart$92494341 997 $aUNINA