LEADER 05352nam 2200661Ia 450 001 9910462131003321 005 20200520144314.0 010 $a1-283-73425-7 010 $a0-12-382220-3 035 $a(CKB)2670000000274590 035 $a(EBL)1058161 035 $a(OCoLC)818819268 035 $a(SSID)ssj0000791439 035 $a(PQKBManifestationID)12387322 035 $a(PQKBTitleCode)TC0000791439 035 $a(PQKBWorkID)10758447 035 $a(PQKB)10323121 035 $a(MiAaPQ)EBC1058161 035 $a(PPN)176533958 035 $a(Au-PeEL)EBL1058161 035 $a(CaPaEBR)ebr10621137 035 $a(CaONFJC)MIL404675 035 $a(EXLCZ)992670000000274590 100 $a20120813d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHandbook of proteolytic enzymes$b[electronic resource] $hVolume 1 /$fedited by, Neil D. Rawlings, Guy Salvesen 205 $a3rd ed. 210 $aOxford $cAcademic$d2012 215 $a1 online resource (3987 p.) 300 $aPrevious ed.: London: Elsevier Academic, 2004. 311 $a0-12-382219-X 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Handbook of Proteolytic Enzymes; Copyright Page; Contents; Editor Biographies; Contributors; Preface; Introduction; Terminology; Organization of the Handbook; Special forms of information in the Handbook; Links to the MEROPS database; Molecular images; Alignments; Secondary structure; Description of substrate specificity; References; Aspartic Peptidases; 1 Introduction: Aspartic and Glutamic Peptidases and Their Clans; Clan AA; Family A1; Other Families in Clan AA; Clan AF; Clan AC; Clan AD; Clan AE; Other Families; Glutamic Peptidases; Asparagine Peptide Lyases 327 $aClans NA, NC and NEInteins; Autotransporters; References; 2 Catalytic Pathways of Aspartic Peptidases; Introduction; Enzymatic Mechanism of Aspartic Peptidases; Enzymatic Mechanism of Glutamic Peptidases; References; 3 Pepsin A; Databanks; Name and History; Activity and Specificity; Structural Chemistry; Pepsinogen; Preparation; Biological Aspects; Related Peptidases; Further Reading; References; 4 Pepsin B; Databanks; Name and History; Activity and Specificity; Structural Chemistry; Preparation; Biological Aspects; Further Reading; References; 5 Chymosin; Databanks; Name and History 327 $aActivity and SpecificityStructural Chemistry; Preparation; Biological Aspects; Distinguishing Features; Related Proteinases; Further Reading; References; 6 Cathepsin E; Databanks; Name and History; Activity and Specificity; Structural Chemistry; Preparation; Biological Aspects; Tissue Distribution and Subcellular Localization; Regulation of Gene Expression; Processing, Maturation and Intracellular Trafficking Of Cathepsin E; Physiological Roles of Cathepsin E; Distinguishing Features; Further Reading; References; 7 Gastricsin; Databanks; Name and History; Activity and Specificity 327 $aStructural ChemistryProgastricsin; Preparation; Biological Aspects; References; 8 Cathepsin D; Databanks; Name and History; Activity and Specificity; Assay Methods; Specificity; Inhibition and Activation; Structural Chemistry; Three-dimensional Structure; Preparation; Biological Aspects; Gene and Expression Control; Knock-out Model; Organ Distribution and Cellular Localization; Apoptosis; Involvement in Cancer; Neurodegeneration; Other Biological Functions; Distinguishing Features; Related Peptidases; Acknowledgment; Further Reading; References; 9 Nothepsin; Databanks; Name and History 327 $aActivity and SpecificityStructural Chemistry; Primary Structure Analysis; Distinguishing Features of This New Class of Aspartic Proteinases; Retrieval and Sequencing of Nothepsin Enzymes; Presence of a Nothepsin Enzyme in Non-Antarctic Fish; Nothepsin in Organisms Other Than Fish; Preparation; Biological Aspects; Expression Pattern of the Nothepsin in Fish and Lizard; Phylogenetic Analysis, Adaptive Evolution and Role of Nothepsin; Further Reading; References; 10 Napsin A; Databanks; Name and History; Activity and Specificity; Structural Chemistry; Preparation; Biological Aspects 327 $aFurther Reading 330 $aThe third edition of the Handbook of Proteolytic Enzymes is a comprehensive reference work for the enzymes that cleave proteins and peptides, written by acknowledged experts in the field and containing over 850 chapters. Each chapter is organized into sections describing the name and history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features for a specific peptidase. There are also introductory chapters on peptidase classification and mechanisms and a comprehensive index. For the first time, the Handbook is also 606 $aProteolytic enzymes 606 $aCellular control mechanisms 608 $aElectronic books. 615 0$aProteolytic enzymes. 615 0$aCellular control mechanisms. 676 $a572.76 701 $aRawlings$b Neil D$0729272 701 $aSalvesen$b G$0911398 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910462131003321 996 $aHandbook of proteolytic enzymes$92041100 997 $aUNINA LEADER 01313nam 2200361Ia 450 001 996394867003316 005 20200824132045.0 035 $a(CKB)3810000000007744 035 $a(EEBO)2240880420 035 $a(OCoLC)ocm18971743e 035 $a(OCoLC)18971743 035 $a(EXLCZ)993810000000007744 100 $a19890105d1662 uy | 101 0 $aeng 135 $aurbn||||a|bb| 200 10$aIdiota's, or, Duns contemplations of divine love$b[electronic resource] /$fwritten by that holy, learned, and renowned man, John Duns, alias Scotus ... ; hereunto is added an abreviate of the authours life, a catalogue of his divine works .. 210 $aPrinted at Paris $c[s.n.]$d1662 215 $a[16], 211 p 300 $aImperfect: tightly bound, with print show-through and some loss of print. 300 $aReproduction of original in the British Library. 330 $aeebo-0018 606 $aLove$xReligious aspects$xChristianity 606 $aGod$xLove 615 0$aLove$xReligious aspects$xChristianity. 615 0$aGod$xLove. 700 $aDuns Scotus$b John$fca. 1266-1308.$0864541 801 0$bEAH 801 1$bEAH 801 2$bWaOLN 906 $aBOOK 912 $a996394867003316 996 $aIdiota's, or, Duns contemplations of divine love$92364083 997 $aUNISA