LEADER 01992nam 2200409 n 450 001 996393055503316 005 20221108053118.0 035 $a(CKB)4940000000114393 035 $a(EEBO)2248574368 035 $a(UnM)9959468000971 035 $a(EXLCZ)994940000000114393 100 $a20790322d1720 uh 101 0 $aeng 135 $aurbn||||a|bb| 200 10$aBy the Lords Justices, a proclamation, ... requiring quarentine to be performed by ships coming from the Mediterranean, Bourdeaux, or any of the ports or places on the coast of France in the Bay of Biscay, or from the isles of Guernsey, Jersey, Alderney, Sarke, or Man$b[electronic resource] 210 $aLondon $cprinted by John Baskett, printer to the Kings most excellent Majesty, and by the assigns of Thomas Newcomb, and Henry Hills, deceas'd$d1720 215 $a1 sheet ([1] p.) 300 $a"Given at Whitehall the twenty seventh day of October, 1720". 300 $aIn this edition the final line of the black letter text begins with "law against ..". 300 $aSteele notation: Silk, such by. There is no press figure. 300 $aReproduction of original in the British Library. 330 $aeebo-0018 606 $aPlague$zGreat Britain$vEarly works to 1800 606 $aQuarantine$zGreat Britain$vEarly works to 1800 607 $aGreat Britain$xHistory$yGeorge I, 1714-1727$vEarly works to 1800 615 0$aPlague 615 0$aQuarantine 701 $aGeorge$cKing of Great Britain,$f1660-1727.$01002174 801 0$bUk-ES 801 1$bUk-ES 801 2$bCu-RivES 801 2$bCStRLIN 801 2$bCu-RivES 906 $aBOOK 912 $a996393055503316 996 $aBy the Lords Justices, a proclamation, ... requiring quarentine to be performed by ships coming from the Mediterranean, Bourdeaux, or any of the ports or places on the coast of France in the Bay of Biscay, or from the isles of Guernsey, Jersey, Alderney, Sarke, or Man$92363098 997 $aUNISA LEADER 04464nam 2201117z- 450 001 9910557141203321 005 20210501 035 $a(CKB)5400000000040647 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68554 035 $a(oapen)doab68554 035 $a(EXLCZ)995400000000040647 100 $a20202105d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aSample Preparation in Metabolomics 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (208 p.) 311 08$a3-03943-813-1 311 08$a3-03943-814-X 330 $aMetabolomics is increasingly being used to explore the dynamic responses of living systems in biochemical research. The complexity of the metabolome is outstanding, requiring the use of complementary analytical platforms and methods for its quantitative or qualitative profiling. In alignment with the selected analytical approach and the study aim, sample collection and preparation are critical steps that must be carefully selected and optimized to generate high-quality metabolomic data. This book showcases some of the most recent developments in the field of sample preparation for metabolomics studies. Novel technologies presented include electromembrane extraction of polar metabolites from plasma samples and guidelines for the preparation of biospecimens for the analysis with high-resolution ? magic-angle spinning nuclear magnetic resonance (HR-?MAS NMR). In the following chapters, the spotlight is on sample preparation approaches that have been optimized for diverse bioanalytical applications, including the analysis of cell lines, bacteria, single spheroids, extracellular vesicles, human milk, plant natural products and forest trees. 606 $aMedicine and Nursing$2bicssc 610 $a20% FCS 610 $aAMOPLS 610 $aAsPC-1 610 $abiomarkers 610 $acapillary electrophoresis-mass spectrometry 610 $acapillary electrophoresis-mass spectrometry (CE-MS) 610 $acardiovascular disease 610 $acell line 610 $adatabases 610 $adesign of experiments 610 $adiagnostics 610 $adrug discovery 610 $aelectromembrane extraction 610 $aexosomes 610 $aextracellular vesicles 610 $aextraction 610 $aforestry 610 $agas chromatography 610 $agas chromatography-mass spectrometry (GC-MS) 610 $aGC-MS 610 $aharvesting 610 $ahigh resolution mass spectrometry 610 $ahigh-resolution magic angle spinning 610 $ahuman cell line 610 $ahuman milk 610 $ahuman plasma 610 $ahydrophilic interaction liquid chromatography 610 $aion mobility spectrometry 610 $aIT-139 610 $aKP1339 610 $aLC-MS 610 $aLC-MS/MS 610 $alipidomics 610 $aliquid chromatography 610 $aliquid chromatography-mass spectrometry 610 $aliquid chromatography-mass spectrometry (LC-MS) 610 $amass spectrometry 610 $ametabolic pathways 610 $ametabolic profiling 610 $ametabolite extraction 610 $ametabolites 610 $ametabolome 610 $ametabolomics 610 $ametabonomics 610 $ametadata standardization 610 $ametallodrugs 610 $amethod development 610 $aMiaPaCa-2 610 $amicroscopic samples 610 $amicrovesicles 610 $amulti-segment injection 610 $amulticellular tumor spheroids 610 $aNMR 610 $anormalization 610 $anuclear magnetic resonance (NMR) 610 $anuclear magnetic resonance spectroscopy 610 $aoxaliplatin 610 $aPanc-1 610 $aplant metabolomics 610 $aplant natural products 610 $asample preparation 610 $asampling 610 $atrees 615 7$aMedicine and Nursing 700 $aKuligowski$b Julia$4edt$01302968 702 $aQuintás$b Guillermo$4edt 702 $aKuligowski$b Julia$4oth 702 $aQuintás$b Guillermo$4oth 906 $aBOOK 912 $a9910557141203321 996 $aSample Preparation in Metabolomics$93026786 997 $aUNINA