LEADER 01378nam 2200397 n 450 001 996389970103316 005 20221107222911.0 035 $a(CKB)1000000000650453 035 $a(EEBO)2240863720 035 $a(UnM)99848211 035 $a(EXLCZ)991000000000650453 100 $a19920102d1599 uy | 101 0 $aeng 135 $aurbn||||a|bb| 200 04$a[The] vrina[l of phy]sicke. Composed by Maister Robert Recorde, Doctor of Phisicke$b[electronic resource] 210 $aImprinted at London $cAt the Three Cranes in the Vintree by Thomas Dawson$d1599 215 $a[160] p. $cdiagrams 300 $aAn edition of: The urinal of physick. 300 $aRunning title reads: The iudicial of vrine. 300 $aSignatures: A-K. 300 $aImperfect; title page mutilated, with some loss of text. 300 $aReproduction of the original in the British Library. 330 $aeebo-0018 606 $aUrine$xAnalysis$vEarly works to 1800 606 $aMedicine$vEarly works to 1800 615 0$aUrine$xAnalysis 615 0$aMedicine 700 $aRecord$b Robert$f1510?-1558.$01003280 801 0$bCu-RivES 801 1$bCu-RivES 801 2$bCStRLIN 801 2$bWaOLN 906 $aBOOK 912 $a996389970103316 996 $aVrinal of physicke. Composed by Maister Robert Recorde, Doctor of Phisicke$92366843 997 $aUNISA LEADER 03457nam 22005655 450 001 9910253916903321 005 20250609111403.0 010 $a3-319-57127-3 024 7 $a10.1007/978-3-319-57127-0 035 $a(CKB)3710000001406131 035 $a(DE-He213)978-3-319-57127-0 035 $a(MiAaPQ)EBC4874789 035 $a(PPN)202991334 035 $a(MiAaPQ)EBC6235500 035 $a(EXLCZ)993710000001406131 100 $a20170609d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCell Division Machinery and Disease /$fedited by Monica Gotta, Patrick Meraldi 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (XIV, 235 p. 33 illus., 32 illus. in color.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1002 311 08$a3-319-57125-7 320 $aIncludes bibliographical references and index. 327 $a1.Meiotic divisions: no place for gender equality -- 2.Consequences of centrosome dysfunction during brain development -- 3.Dividing with extra centrosomes: a double edged sword for cancer cells -- 4.Kinetochore malfunction in human pathologies -- 5.The elephant in the room: the role of microtubules in cancer -- 6.Clinical development of anti-mitotic drugs in cancer -- 7.Mitotic dysfunction associated with aging hallmarks -- 8.Unbalanced Growth, Senescence and Aging -- 9.The spindle orientation machinery beyond mitosis: when cell specialization demands polarization. 330 $aThis book critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the means for exploring them. Throughout the various chapters, internationally known contributors present the evidence for and against a causal link between key elements of the cell division machinery and diseases such as cancer, neuropathologies, aging, and infertility. A more clinically oriented chapter further discusses the current and future applications of anti-mitotic drugs in these diseases. Cell Division Machinery and Disease is essential reading for graduate or advanced graduate students, researchers or scientists working on cell division as well as clinicians interested in the molecular mechanisms of the discussed diseases. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1002 606 $aCell cycle 606 $aCell physiology 606 $aCancer$xResearch 606 $aCell Cycle Analysis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16030 606 $aCell Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33010 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 615 0$aCell cycle. 615 0$aCell physiology. 615 0$aCancer$xResearch. 615 14$aCell Cycle Analysis. 615 24$aCell Physiology. 615 24$aCancer Research. 676 $a571.84 702 $aGotta$b Monica$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMeraldi$b Patrick$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253916903321 996 $aCell Division Machinery and Disease$92065490 997 $aUNINA