LEADER 01662nam 2200397Ia 450 001 996389391903316 005 20210104171909.0 035 $a(CKB)4940000000098087 035 $a(EEBO)2240855404 035 $a(OCoLC)ocn949007309e 035 $a(OCoLC)949007309 035 $a(EXLCZ)994940000000098087 100 $a20160509d1697 uy 0 101 0 $aeng 135 $aurbn||||a|bb| 200 10$aTo the right honourable the lords spiritual and temporal in Parliament assembled$b[electronic resource] $ereasons humbly offered for passing of the engrossed bill, for suppressing of hawkers and pedlars 210 $a[London, England $cs.n.]$dprinted March 20. 96 [i.e. 1697] 215 $a1 sheet ([1] p.) 300 $aDate of publication from foot of text; signed at foot: Charles Palmer. 300 $aPlace of publication suggested by Wing (2nd ed. 1994). 300 $aReproduction of original in: Guildhall Library (London, England). 330 $aeebo-0059 606 $aPeddling$xLaw and legislation$zGreat Britain$vEarly works to 1800 606 $aStreet vendors$zGreat Britain$vEarly works to 1800 607 $aGreat Britain$xPolitics and government$y1689-1702$vSources 608 $aBroadsides$zEngland$y17th century.$2rbgenr 615 0$aPeddling$xLaw and legislation 615 0$aStreet vendors 700 $aPalmer$b Charles$f1663?-1734.$01009450 712 02$aEngland and Wales.$bParliament.$bHouse of Lords. 801 0$bUMI 801 1$bUMI 906 $aBOOK 912 $a996389391903316 996 $aTo the right honourable the lords spiritual and temporal in Parliament assembled$92331132 997 $aUNISA LEADER 03784nam 2200637 450 001 9910686476203321 005 20230824003845.0 010 $a3-031-22802-2 024 7 $a10.1007/978-3-031-22802-5 035 $a(CKB)5590000001037692 035 $a(DE-He213)978-3-031-22802-5 035 $a(MiAaPQ)EBC7236621 035 $a(Au-PeEL)EBL7236621 035 $a(PPN)269656650 035 $a(EXLCZ)995590000001037692 100 $a20230731d2023 uy 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEngineering and physical approaches to cancer /$fIan Y. Wong and Michelle R. Dawson, editors 205 $aFirst edition 2023. 210 1$aCham, Switzerland :$cSpringer Nature Switzerland AG,$d[2023] 210 4$dİ2023 215 $a1 online resource (VIII, 331 pages, 60 illustrations, 57 illustrations in color) $cillustrations 225 1 $aCurrent Cancer Research,$x2199-2592 311 $a3-031-22801-4 320 $aIncludes bibliographical references and index. 327 $aChapter 1. EMT -- Chapter 2. Nuclear/Chromatin Mechanics -- Chapter 3. Cell level mechanical changes -- Chapter 4. Physical aspects related to metabolism -- Chapter 5. Mechanical tropism / Physical aspects of seed and soil -- Chapter 6. Tumor microenvironment interactions -- Chapter 7. Extracellular Matrix -- Chapter 8. Physical Assays Focused on Tumor Heterogeneity -- Chapter 9. Ecology / evolution of the tumor microenvironment -- Chapter 10. Spatial transcriptomics / proteomics in the Human Tumor Atlas. 330 $aEngineering and Physical Approaches to Cancer addresses the newest research at this interface between cancer biology and the physical sciences. Several chapters address the mechanobiology of collective and individual cell migration, including experimental, theoretical, and computational perspectives. Other chapters consider the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, including the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells. Further, chapters focus on circulating tumor cells and metastatic colonization, highlighting both bioengineered models as well as diagnostic technologies. Further, this book features the work of emerging and diverse investigators in this field, who have already made impressive cross-disciplinary scientific contributions. This book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of interest to medical professionals and trainees, as well as researchers in the pharmaceutical and biomedical device industry. 410 0$aCurrent Cancer Research,$x2199-2592 606 $aBiomechanics 606 $aCancer$xImaging 606 $aCancer$xTreatment 606 $aBiomechanical Phenomena 606 $aTumor Microenvironment 606 $aExtracellular Matrix 606 $aNeoplasms 615 0$aBiomechanics. 615 0$aCancer$xImaging. 615 0$aCancer$xTreatment. 615 2$aBiomechanical Phenomena. 615 2$aTumor Microenvironment. 615 2$aExtracellular Matrix. 615 2$aNeoplasms. 676 $a612.76 702 $aWong$b Ian Y. 702 $aDawson$b Michelle R. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910686476203321 996 $aEngineering and Physical Approaches to Cancer$93089332 997 $aUNINA